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Description
VE-Cadherin Recombinant Rabbit mAb (S-1291-239)Product Specification Host Rabbit Antigen CD144 Synonyms Cadherin 5; 7B4 antigen; Vascular endothelial cadherin (VE cadherin); CDH5 Immunogen Synthetic Peptide Location Cytoplasm, Cell membrane Accession P33151 Clone Number S 1291 239 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Ms, Rt Positive Sample mouse heart, rat heart Predicted Reactivity Pg, Ck Purification Protein A Concentration 0. 5 mg ml Conjugation
Product Specification
| Host | Rabbit |
| Antigen | CD144 |
| Synonyms | Cadherin-5; 7B4 antigen; Vascular endothelial cadherin (VE-cadherin); CDH5 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Cell membrane |
| Accession | P33151 |
| Clone Number | S-1291-239 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Ms, Rt |
| Positive Sample | mouse heart, rat heart |
| Predicted Reactivity | Pg, Ck |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Ms, Rt |
| IHC-P | 1:2000 | Ms, Rt |
Background
CD144, also termed VE-cadherin or cadherin-5, is a 140 kDa calcium-dependent type-II classical cadherin expressed almost exclusively on vascular and lymphatic endothelial cells, where it forms the core of adherens junctions by mediating homophilic trans-interactions between neighboring cells and anchoring to the actin cytoskeleton via catenins (β-, γ-, and p120-catenin), thereby controlling endothelial barrier integrity, vascular permeability, leukocyte extravasation, and embryonic angiogenesis, while also modulating VEGF receptor signaling, cell polarity, and lumen formation.
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4.3 ★★★★★
Based on 29 reviews
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Product Reviews
★★★★★ 5
Highly Recommend to anyone going through family conflicts
Format: Hardcover
I love all of Nedra’s books. I highly recommend this book to anyone who has family conflicts that are taking a toll on them. It teaches you how to set proper boundaries and understand the situation and your feelings.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 25, 2026
★★★★★ 5
Practical Read for Managing Challenging Family Dynamics
Format: Hardcover
I found this text easy to read and a helpful way to reflect on my childhood experience and the relationships I have with my family members. The strategies are easy to implement.
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Reviewed in the United States on January 21, 2026
★★★★★ 5
Drama Free For Sure!
Format: Kindle
Nedra Glover Tawwab is a New York Times bestselling author, a licensed therapist, and a sought-after relationship expert. This book is a therapeutic and educational tool that addresses how to consciously change behaviors you’d rather not have in relationships, specifically, around your family. For those of us who have delved into the self-help book world, this is an in-depth, thorough refresher, focusing on family dynamics.
Nedra’s core belief is that relationships contribute to mental health. They can cause you pain or they heal you. She focuses on taking your relationships seriously and teaches the art of having tough but intentional conversations to create positive change. OR you’ll learn how to sever ties when the relationship is unmanageable.
None is more influential than the formative years we’ve had with our family of origin. A lot of people lament that not everything is about the family, but yup, so often it’s true. In childhood, most likely we weren’t allowed to be ourselves, so our true selves started to develop when becoming an adult. Like a butterfly using its colossal strength to break out of its chrysalis, we too must use our emotional colossal strength to break out of our childhood mold in order to fly. We are able to have relationships with family on our terms.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 11, 2023
★★★★★ 4
Insightful and Compassionate.
Format: Hardcover
I really love Nedra Glover Tawwab's work. I started with "Set Boundaries, Find Peace" and that opened the gateway to a broader and more helpful healing journey for me. This book, "Drama Fee" was just an evolutionary step in her series and a more in depth dealing with family relationships. The different perspectives for each chapter on how the concept can be applied was/is helpful as it often feels like books of this nature are only telling the black or white way to focus on a relationship. I felt seen and heard that though my familial relationships are unique there are commonalities and in turn ways to approach healing, reconciliation (with oneself and with family), understanding and compassion, to a achieve drama free relationships. As humans we are bread for connection and I appreciate Nedra Glover Tawwab's help in navigating them.
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Reviewed in the United States on June 9, 2025
★★★★★ 5
Being Our True Selves In Relationships That Matter
Format: Kindle
Nedra Glover Tawwab is a New York Times bestselling author, a licensed therapist, and a sought-after relationship expert. This book is a therapeutic and educational tool that addresses how to consciously change behaviors you’d rather not have in relationships, specifically, around your family. For those of us who have delved into the self-help book world, this is an in-depth, thorough refresher, focusing on family dynamics.
Nedra’s core belief is that relationships contribute to mental health. They can cause you pain or they heal you. She focuses on taking your relationships seriously and teaches the art of having tough but intentional conversations to create positive change. OR you’ll learn how to sever ties when the relationship is unmanageable.
None is more influential than the formative years we’ve had with our family of origin. A lot of people lament that not everything is about the family, but yup, so often it’s true. In childhood, most likely we weren’t allowed to be ourselves, so our true selves started to develop when becoming an adult. Like a butterfly using its colossal strength to break out of its chrysalis, we too must use our emotional colossal strength to break out of our childhood mold in order to fly. We are able to have relationships with family on our terms.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 3, 2023