Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 9 - Jul 14
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
PE-Cy7 Rat Anti-Mouse/Human CD11b Antibody (S-R574)Product Specification Host Rat Antigen CD11b Synonyms Integrin alpha M; CD11 antigen like family member B; CR 3 alpha chain; Cell surface glycoprotein MAC 1 subunit alpha; Leukocyte adhesion receptor MO1; Itgam Location Cell membrane Accession P05555 Clone Number S R574 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Hu, Ms Positive Sample C57BL 6 mouse bone marrow Purification Protein G Concentration 0. 1 mg ml Conjugation PE Cy7
Product Specification
| Host | Rat |
| Antigen | CD11b |
| Synonyms | Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Itgam |
| Location | Cell membrane |
| Accession | P05555 |
| Clone Number | S-R574 |
| Antibody Type | Rat mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Hu, Ms |
| Positive Sample | C57BL/6 mouse bone marrow |
| Purification | Protein G |
| Concentration | 0.1 mg/ml |
| Conjugation | PE-Cy7 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1μl per million cells in 100μl volume | Hu, Ms |
Background
CD11b, also known as integrin alpha M (ITGAM), is a cell surface receptor belonging to the integrin family and primarily expressed on immune cells such as macrophages, monocytes, neutrophils, and NK cells. It forms a heterodimer with CD18 to create the β2 integrin complex, which is crucial for mediating cell adhesion, migration, and immune responses. CD11b plays a significant role in leukocyte recruitment and activation during inflammation and immune responses by interacting with ligands like ICAM-1 and iC3b. Additionally, it is involved in phagocytosis and immune regulation in various diseases, including cancer and autoimmune conditions.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy