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Description
Alexa Fluor 647-Labeled CD20 Flag&His Tag Full Length Protein, Human (Detergent)Product Specification Species Human Synonyms B lymphocyte surface antigen B1MS4A1B lymphocyte antigen CD20Membrane Spanning 4 Domains A1Leukocyte Surface Antigen Leu 16CD20 AntigenCD20Bp35Membrane Spanning 4 Domains Subfamily A Member 1CD20 ReceptorLEU 16CVID5MS4A2B1S7Antigens CD20Membrane Spanning 4 Domains Subfamily A Member 1B Lymphocyte Cell Surface Antigen B1 Accession P11836 Amino Acid Sequence Full length, with Flag tag at N Terminus, and His
Product Specification
| Species | Human |
| Synonyms | B-lymphocyte surface antigen B1，MS4A1，B-lymphocyte antigen CD20，Membrane Spanning 4-Domains A1，Leukocyte Surface Antigen Leu-16，CD20 Antigen，CD20，Bp35，Membrane-Spanning 4-Domains Subfamily A Member 1，CD20 Receptor，LEU-16，CVID5，MS4A2，B1，S7，Antigens， CD20，Membrane-Spanning 4-Domains， Subfamily A， Member 1，B-Lymphocyte Cell-Surface Antigen B1 |
| Accession | P11836 |
| Amino Acid Sequence | Full length, with Flag tag at N-Terminus, and His tag at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 35.4 kDa |
| Conjugation | Alexa Fluor® 647 |
| Tag | His Tag, Flag Tag |
| Physical Appearance | Liquid |
| Storage Buffer | 25mM Hepes,150mM NaCl,0.02%DDM |
| Stability & Storage |
· 16 months from date of receipt stored at -80℃. |
| Reference | 1. Rougé L, Chiang N, Steffek M, et al. Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab[J]. Science, 2020, 367(6483): 1224-1230. |
Background
CD20 is a 33-37 kDa non-glycosylated protein present on the surface of normal and malignant B lymphocytes and is a member of the MS4A (membrane-spanning 4-domain family A) protein family. The CD20 protein comprises four hydrophobic transmembrane domains, one intracellular domain, and two extracellular domains (a large loop and a small loop), with both the N- and C-termini located within the cytosol. CD20 is associated with several key molecules, including the major histocompatibility complex class II (MHCII), CD40 molecule, B-cell receptor (BCR), and the C-terminal src kinase-binding protein (CBP). CBP interacts with Src kinases such as LYN, FYN, and LCK.A deficiency in CD20 has been shown to result in a reduced number of circulating memory B cells, decreased isotype switching of immunoglobulins (Ig), and lower IgG antibody levels. It is also linked to various pathophysiological diseases and disorders.CD20 plays a crucial role in multiple physiological processes and is thus a promising therapeutic target. The CD20 protein product has the potential to enhance drug discovery efforts in related fields.
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4.9 ★★★★★
Based on 30 reviews
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Product Reviews
★★★★★ 5
Wow. Explosion of froth and mouthwash in one little tablet.
Flavor Name: 2-Bottle Green Tea
I love these for travel, and put some in a tiny container in my purse, too. You just have to spit it out - no rinse necessary. I might try a different flavor than the green tea. Don't love it, but do love the product.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 9, 2026
★★★★★ 5
Really good book, easy and clear!
Format: Kindle
Oh, we've all heard of manifestation. Frankly, as an older guy and a retired Marine, I kinda cringe when I hear the word. "Something sissies would say," I'd think. Not that I'm a garage guy or anything. I just believe in faith and hard work! But, I decided to explore this book and was quite humored that manifestation is pretty much a compendium of concepts familiar to me since all I know are founded on The Bible and The Marine Officer's Guidebook. Wink. But seriously, I do believe in Universal Laws that Apply Universally, and manifestation, as portrayed in this book, is pretty much about that. The author does reference principles found in Christianity and Hinduism, for instance. But also physics and psychology. Practices such as visualization, gratitude and love (law of vibration, love that). So good. I'm going to get this book for my kids, since I can't get them to read the Bible, perhaps they'll read this! Seriously, it's a great complement to God's principles and not nearly so hard to mine. ; )
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Reviewed in the United States on September 4, 2024
★★★★★ 5
Informative and Effective!
Format: Kindle
I’ve practiced the art of manifestation a few times, and it’s something I want to use more in my day-to-day life, so this book was the perfect introduction and deep dive into what it truly is. This is a comprehensive and helpful guide to manifestation—an amazing first step to improving your life and building one of prosperity, happiness, and whatever you desire. Manifestation can seem intimidating, but this book simplifies the act of it and the methods needed to turn your desires into reality. In this book, you'll find all of the steps and advice needed to change your life through manifestation, but it is us, the readers, who now need to use these steps and methods to change and better our lives. I highly enjoyed and recommend this read to anyone, honestly, as manifestation is something I think we can all use in our lives!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 9, 2024
★★★★★ 4
Practical Roadmap to Your Dreams
Format: Kindle
Ingrid Clarke has written a thorough and well-sequenced book to open up our minds to this transformational process.
This is a step-by-step guide, via the seven pillars, to bringing dreams into reality - a popular topic. It’s a reminder that we often miss out on certain of these steps and fall short of achieving our dreams - sometimes blaming the methodology rather than ourselves for the shortfall!
I liked that processes were shown to help maintain a high vibration, to better put the steps into practice, and that ‘there is a powerful energy already inherent in you.’
With the first three pillars in place, the intention, visualization, and affirmation work flowed well, with examples to guide the reader. The puzzle pieces were brought together so that an overall view of the method could be clearly seen. I would recommend the book.
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Reviewed in the United States on December 19, 2024
★★★★★ 5
Great Read
Format: Kindle
In Ingrid Clarke’s book, she gives beginners 107 techniques to use to harness their power of manifestation. She provides a deeper understanding of what manifestation is and how you can utilize it in your life easily. Clarke says that you can align your beliefs with your dreams and create the change you want to see in your life. Two of my favorite techniques for this mentioned in the book are affirmations and visualization. These are what I plan to utilize to manifest prosperity and success in my life. I love how Clarke gives you the step-by-step of how to go from wanting something in your life to getting it through manifestation. My other favorite part of this book was how I learned to have a deeper connection with myself.
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Reviewed in the United States on February 21, 2024
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