SKU: 14685423751

FGF-6 Protein, Human

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Description

FGF-6 Protein, HumanProduct Specification Species Human Synonyms Fibroblast growth factor 6, FGF 6, Heparin secretory transforming protein 2 (HST 2; HSTF 2), Heparin binding growth factor 6 (HBGF 6) Accession P10767 Amino Acid Sequence Gly41 Ile208 Expression System E. coli Molecular Weight 14 15 kDa (Reducing) Purity >95% by SDS PAGE, >90% by HPLC. Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized powder Storage Buffer PBS, pH7. 4

Product Specification


Species Human
Synonyms Fibroblast growth factor 6, FGF-6, Heparin secretory-transforming protein 2 (HST-2; HSTF-2), Heparin-binding growth factor 6 (HBGF-6)
Accession P10767
Amino Acid Sequence

Gly41-Ile208
Expression System E.coli
Molecular Weight

14-15 kDa (Reducing)
Purity >95% by SDS-PAGE, >90% by HPLC.
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized powder
Storage Buffer

PBS, pH7.4
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage

·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
·3 months, -20 to -80℃ under sterile conditions after reconstitution.
·1 week, 2 to 8℃ under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.
Reference

Genes & Dev. 1997;11(16):2040-2051.
Nat Commun. 2020;11(1):1421.

Background

Fibroblast growth factor 6 (FGF-6), also designated as HST2 or HBGF-6, is a secreted peptide growth factor belonging to the paracrine FGF subfamily. The FGF6 gene, located on human chromosome 12p13, encodes an 18.9 kDa protein that exhibits the highest expression in skeletal muscle and myogenic progenitor cells throughout embryonic development and adulthood. FGF-6 binds preferentially to fibroblast growth factor receptor 4 (FGFR4) with heparan sulfate proteoglycan co-receptor dependency, triggering downstream signaling through the MAPK/ERK1/2 and PI3K/AKT pathways.Functionally, FGF-6 operates as a dose-dependent regulator of myogenesis, promoting satellite cell proliferation at high concentrations and initiating myogenic differentiation via calcineurin-dependent pathways at lower concentrations. Beyond muscle physiology, FGF-6 exhibits pleiotropic functions in bone remodeling, iron homeostasis, thermogenesis, and oncogenesis, harboring both regenerative and tumorigenic activities.
Shipping Notes
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Exchange/Return Notes
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SKU: 14685423751

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4.1 ★★★★★
Based on 10 reviews
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C
Verified Purchase
Chris F.
Bozeman, US
★★★★★ 5
Excellent tray
Color: Sand Brown, Size: 9.5in x 7.9in
This is an exceptionally high-quality tray. The design was well thought out and it looks amazing. I keep it in my top dresser drawer to organize extra cards for my wallet, my watch, cufflinks, and other items. I can’t say enough about the high level of quality. It stays in place, has great storage and very reasonably priced I thought.
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Reviewed in the United States on August 15, 2025
D
Verified Purchase
Dunn
Omaha, US
★★★★★ 4
Good purchase
Color: Sand Brown, Size: 9.5in x 7.9in
Bought for my husbands desk, it looks nice and good quality for the price
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 7, 2026
S
Verified Purchase
Saarah
Dallas, US
★★★★★ 5
Luxurious
Color: Sand Brown, Size: 9.5in x 7.9in
Firstly, I was very impressed by the packaging and attention to detail, from the box to the lovely wrapping. I purchased the brown and the tray is beautiful with the two-tone. I love the tree imprint on the inside. It looks very rich and the leather has a great feel to it. I also like that the logo was imprinted at the bottom/back. This would make a great gift. Great product!
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Reviewed in the United States on August 1, 2025
C
Verified Purchase
Concerned Buyer
Houston, US
★★★★★ 5
Looks good, feels good for my pocket.
Good price, while still being stylish. Slots fit all my major items shown above and now I cannot live without it.
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Reviewed in the United States on May 18, 2025
A
Verified Purchase
Akwei Bortey
New York, US
★★★★★ 5
Functional and aesthetic
Does what you expect it to do. Great for organizing, very functional and very easy to incorporate into your table design.
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Reviewed in the United States on April 26, 2025

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