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Description
ROR1 Fc Chimera Protein, MouseProduct Specification Species Mouse Accession Q9Z139 Amino Acid Sequence Gln30 Glu403, with C terminal Human IgG Fc
Product Specification
| Species | Mouse |
| Accession | Q9Z139 |
| Amino Acid Sequence | Gln30-Glu403, with C-terminal Human IgG Fc QETELSVSAELVPTSSWNTSSEIDKGSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPSIRWFKNDAPVVQEPRRISFRATNYGSRLRIRNLDTTDTGYFQCVATNGKKVVSTTGVLFVKFGPPPTASPGSSDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEVLENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHSFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPACDSKDSKEKNKMEIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Expression System | HEK293 |
| Molecular Weight | 90-95kDa (Reducing) |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
Receptor tyrosine kinase-like orphan receptors (RORs) are monotopic membrane proteins belonging to the receptor tyrosine kinase (RTK) family. RTKs play a role in the control of most basic cellular processes, including cell proliferation, differentiation, migration and metabolism. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is highly expressed in a wide variety of hematological and solid cancers but is low or absent in adult tissues. ROR1 could interact with casein kinase 1 epsilon (CK1ε) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB). Studies have demonstrated that it plays an important role in oncogenesis by activating cell survival signaling events, particularly the non-canonical WNT signaling pathway. Antibody-based immunotherapies targeting ROR1 have been developed and evaluated in preclinical and clinical studies with promising outcomes.
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Exchange/Return Notes
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4.9 ★★★★★
Based on 25 reviews
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Product Reviews
★★★★★ 4
Affordable Roborock Qrevo CurvX Accessories That Fit Well
Size: Saros 10R/Qrevo CurvX/Edge 2 Accessories, Size: Saros 10R/Qrevo CurvX/Edge 2 Accessories
I have a Roborock Qrevo CurvX vacuum cleaner, so when I saw this replacement parts pack, I wanted to give it a try.
The box contained everything needed to carry out the maintenance schedule recommended in the Roborock app. It even included a small screwdriver, which made changing the side brush easy — a thoughtful extra touch.
I compared all of the replacement parts to the original ones and didn’t notice any major differences. Overall, the parts do seem slightly lower in quality than the originals, but not to the extent that I think it will significantly affect performance or durability.
I replaced the side brush without any issues, and it fit properly.
The mop pads were softer and fluffier than the originals and didn’t fit quite as snugly, although I don’t think this will have much impact on cleaning performance.
The new filter installed perfectly, and the vacuum bags also fit as expected.
Overall, I’m happy with this product. It’s reasonably priced and represents good value for money. I can see myself continuing to use these replacement parts in the future. I’m taking one star off due to the parts being of slightly lower quality
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 13, 2026
★★★★★ 5
Value replacements
Size: Saros 10R/Qrevo CurvX/Edge 2 Accessories
As far as I can tell these are pretty solid replacements for the SAROS 10R. My original side brush was all torn up after just a few months of use so I found these replacement parts. Haven’t used the mop pads yet, but they are a similar design to the “upgraded” mop pads offered by Roborock which are superior to the standard one IMO. Everything else seems to be equal quality to the OEM parts, and at less than $12 I have no complaints on this kit.
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Reviewed in the United States on December 31, 2025
★★★★★ 1
Does not work for Qrevo Arc.
Size: Saros 10R/Qrevo CurvX/Edge 2 Accessories, Size: Saros 10R/Qrevo CurvX/Edge 2 Accessories
Filter does not fit my Qrevo Arc. Photo shows size comparison between my old (very dirty) filter and the replacement filter.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 6, 2026
★★★★★ 4
Solid replacement parts kit — just skip the mop pads
Size: Saros 10R/Qrevo CurvX/Edge 2 Accessories, Size: Saros 10R/Qrevo CurvX/Edge 2 Accessories
This kit has been a handy all-in-one refresh for my robot vacuum. The main brush, side brushes, filters, and dust bags all fit correctly on my Qrevo, slid in without fuss, and have been performing on par with the originals — suction feels unchanged, the side brushes kick debris toward the intake properly, and the filters look and seat identically to the ones they replaced. My one real complaint is the mop pads. They're noticeably thinner and flimsier than the OEM pads, don't hold water as well during a run, and left streakier lines on my floors compared to what I'm used to. I've ended up going back to the original-brand mop cloths and just using this kit for the dry-cleaning parts, which have genuinely been a good value. Four stars — great kit minus the mops.
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Reviewed in the United States on April 15, 2026
★★★★★ 5
Great value
Size: Saros 10R/Qrevo CurvX/Edge 2 Accessories
As advertised
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 8, 2026
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