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Description
Human IFN-β OneStep ELISA KitProduct Specification Antigen IFN Immunogen Recombinant Protein Antibody Type Recombinant mAb Reactivity Hu Purification Protein A Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied. Kit Precision Intra assay: 4. 3% Inter assay: 6. 1% Sample type Cell culture supernatant Assay type Sandwich (quantitative) Sensitivity 1. 926 pg ml Range 7. 81 pg mL 500 pg mL Recovery Cell culture supernatant: 97% Assay time 60
Product Specification
| Antigen | IFN-β |
| Immunogen | Recombinant Protein |
| Antibody Type | Recombinant mAb |
| Reactivity | Hu |
| Purification | Protein A |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Kit
| Precision | Intra-assay: 4.3%； Inter-assay: 6.1% |
| Sample type | Cell culture supernatant |
| Assay type | Sandwich (quantitative) |
| Sensitivity | 1.926 pg/ml |
| Range | 7.81 pg/mL – 500 pg/mL |
| Recovery | Cell culture supernatant: 97% |
| Assay time | 60 minutes |
| Species reactivity | Human |
Background
Human Interferon Beta (IFNβ) is a naturally occurring cytokine belonging to the type I interferon family, primarily produced by fibroblasts and immune cells in response to viral infections or other inflammatory stimuli. It plays a critical role in the innate immune response by binding to the IFNα/β receptor (IFNAR), activating the JAK-STAT signaling pathway, and inducing the expression of interferon-stimulated genes (ISGs). These genes exert broad antiviral, immunomodulatory, and antiproliferative effects. IFNβ has been widely utilized as a therapeutic agent, particularly in the treatment of relapsing-remitting multiple sclerosis (MS), where it helps reduce inflammation and modulate immune activity. Recombinant forms of IFNβ (e.g., IFNβ-1a and IFNβ-1b) are clinically approved and demonstrate efficacy in decreasing relapse rates and slowing disease progression. Key functions of IFNβ include: Antiviral Activity: Enhances cellular resistance to viral infections. Immunoregulation: Suppresses pro-inflammatory cytokines (e.g., TNFα, IL-12) and promotes anti-inflammatory responses. Antiproliferative Effects: Inhibits the growth of certain tumor cells.
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