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Description
PSD-95 Recombinant Rabbit mAb (SDT-1518-140)Product Specification Host Rabbit Antigen PSD 95 Synonyms Disks large homolog 4; Postsynaptic density protein 95 (PSD 95); Synapse associated protein 90 (SAP 90; SAP90); Dlgh4; Psd95; Dlg4 Immunogen Recombinant Protein Accession Q62108 Clone Number SDT 1518 140 Antibody Type Recombinant mAb Isotype IgG Application Sandwich ELISA Reactivity Hu Cross Reactivity No cross reactivity against SNAP25, NFL, GFAP, Tau, UCHL1 Purification Protein A
Product Specification
| Host | Rabbit |
| Antigen | PSD-95 |
| Synonyms | Disks large homolog 4; Postsynaptic density protein 95 (PSD-95); Synapse-associated protein 90 (SAP-90; SAP90); Dlgh4; Psd95; Dlg4 |
| Immunogen | Recombinant Protein |
| Accession | Q62108 |
| Clone Number | SDT-1518-140 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Hu |
| Cross Reactivity | No cross-reactivity against SNAP25, NFL, GFAP, Tau, UCHL1 |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
PSD-95 (postsynaptic density protein 95) is a 95-kDa scaffolding protein enriched in the postsynaptic density of excitatory synapses, where its three N-terminal PDZ domains, an SH3 domain, and a C-terminal guanylate kinase-like domain assemble transmembrane receptors, ion channels, adhesion molecules, and downstream signaling enzymes into a dynamic macromolecular signaling lattice that couples synaptic activity to postsynaptic potentiation or depression and whose dysregulation contributes to autism, schizophrenia, and stroke.
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Exchange/Return Notes
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