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Description
FABP4 His Tag, HumanProduct Specification Species Human Accession P15090 Amino Acid Sequence Cys2 Ala132, with N terminal 8*His MHHHHHHHHCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA Expression System E. coli Molecular Weight 6kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM Tris, 100mM
Product Specification
| Species | Human |
| Accession | P15090 |
| Amino Acid Sequence | Cys2-Ala132, with N-terminal 8*His MHHHHHHHHCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA |
| Expression System | E.coli |
| Molecular Weight | 6kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20mM Tris, 100mM NaCl, pH8.0 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
Fatty acid binding protein 4(FABP4) is an adipocyte-type fatty acid binding protein, which is mainly highly expressed in adipocytes and macrophages. FABP4 is a chaperone molecule in the transport process of intracellular free fatty acids. FABP4 can bind to free fatty acids and transport them into cells. At the same time, FABP4 is involved in the regulation of gene expression, cell proliferation, differentiation and signal transduction of tumor metastasis. It is involved in the interaction between fat and tumor tissue, including lipid transfer between adipocytes and tumor cells, and provides fatty acids required for tumor growth. It is regarded as a potential factor for association between obesity and tumor.
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