Pay in installments of $40.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 23 - Aug 28
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
IFN-gamma R1/IFNGR1 Fc Chimera Protein, HumanProduct Specification Species Human Synonyms CD119,CDw119,IFNGR,IFN gamma R1,IMD27A,IMD27B Accession P15260 Amino Acid Sequence Glu18 Gly245 with hIgG1 Fc Tag at the C Terminus Expression System HEK293 Molecular Weight 60 72kDa (Reducing) Purity 95% by SDS PAGE & > 90% SEC HPLC Conjugation Unconjugated Tag Human IgG1 Fc Physical Appearance Lyophilized powder Storage Buffer PBS, PH7. 4, 5% trehalose Reconstitution Reconstitute at 0. 1 1 mg ml according
Product Specification
| Species | Human |
| Synonyms | CD119,CDw119,IFNGR,IFN-gamma-R1,IMD27A,IMD27B |
| Accession | P15260 |
| Amino Acid Sequence | Glu18-Gly245 with hIgG1 Fc Tag at the C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 60-72kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & > 90% SEC-HPLC |
| Conjugation | Unconjugated |
| Tag | Human IgG1 Fc |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1.Varol SE, Cinar C, Burtecene N, Sahin S, Yildiz M, Barut K, Cokugras H, Firtina S, Kasapcopur O, Kiykim A. Patients With IgA Vasculitis and Kawasaki Disease Show Dysregulated Interferon Signature. Int J Rheum Dis. 2025 Jul;28(7):e70349. |
Background
CD119 (also known as IFNGR1) is the alpha-chain ligand-binding receptor for interferon-gamma, belonging to the type II cytokine receptor family. Its structure comprises two fibronectin type-III domains and two immunoglobulin-like C2-type domains. Together with IFNGR2, it forms a functional heterodimeric receptor, typically with two receptor molecules binding one IFNγ dimer. This receptor mediates signals from interferon-gamma produced by activated T lymphocytes, triggering antiviral activity, inhibition of cell proliferation, and broad immunoregulatory functions in various cell types. Deficiency in its function is associated with certain primary immunodeficiency disorders and holds significant clinical relevance in infection immunity, tumor immunity, and autoimmune diseases.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy