SKU: 65972119285

Alexa Fluor® 488 Mouse Anti-Rat CD1d Antibody (S-R701)

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Description

Alexa Fluor® 488 Mouse Anti-Rat CD1d Antibody (S-R701)Product Specification Host Mouse Antigen CD1d Synonyms Antigen presenting glycoprotein CD1d; Cd1d1; Cd1d Location Cell membrane, Endoplasmic reticulum Accession Q63493 Clone Number S R701 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Rt Positive Sample Lewis Rat thymocytes Purification Protein A Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability &

Product Specification


Host Mouse
Antigen CD1d
Synonyms Antigen-presenting glycoprotein CD1d; Cd1d1; Cd1d
Location Cell membrane, Endoplasmic reticulum
Accession Q63493
Clone Number S-R701
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Rt
Positive Sample Lewis Rat thymocytes
Purification Protein A
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Rt

Background

CD1d is a non-polymorphic, MHC class I-like molecule encoded by the CD1D gene, which is a member of the CD1 family of glycoproteins expressed on the surface of various human antigen-presenting cells. It presents lipid antigens, including phospholipids and glycosphingolipids, to a subset of T cells known as invariant natural killer T (iNKT) cells. When activated by CD1d-presented antigens, iNKT cells rapidly produce Th1 and Th2 cytokines, such as interferon-gamma and interleukin-4. CD1d is also involved in the selection and regulation of iNKT cells. Some known ligands for CD1d include α-galactosylceramide (α-GalCer), a compound derived from a marine sponge, and various microbial and self-antigens.

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SKU: 65972119285

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