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Description
Biotinylated Siglec-4a His&Avi Tag Protein, HumanProduct Specification Species Human Synonyms MAG, Siglec 4a, GMA, S MAG Accession P20916 1 Amino Acid Sequence Gly20 Pro516, with C terminal 10*His&Avi tag
Product Specification
| Species | Human |
| Synonyms | MAG, Siglec-4a, GMA, S-MAG |
| Accession | P20916-1 |
| Amino Acid Sequence | Gly20-Pro516, with C-terminal 10*His&Avi tag GHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGPGGGSGGGSHHHHHHHHHHGLNDIFEAQKIEWHE |
| Expression System | HEK293 |
| Molecular Weight | 80-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Läubli H. et al. (2020) Sialic acid–binding immunoglobulin-like lectins (Siglecs) detect self-associated molecular patterns to regulate immune responses, Cellular and Molecular Life Sciences.77: 593-605. |
Background
Sialic acid-binding immunoglobulin-like lectins (Siglecs) are cell surface receptors of the I-type lectin family that are expressed on innate immune cells and bind to sialylated and non-sialylated ligands. Myelin-Associated Glycoprotein (MAG), also known as Siglec-4a, is a type I transmembrane glycoprotein belonging to the Siglec family, a subgroup of the Ig superfamily. It is selectively expressed by myelinating cells including Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS). It is encoded by a single gene that is conserved among vertebrates. It is composed of an extracellular segment containing five Ig-like domains, a single transmembrane segment, and a cytoplasmic domain. Mature MAG exists as two isoforms, termed S-MAG (short) and L-MAG (long), due to alternative splicing of the cytoplasmic domain.
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The is Genuine BMW branded oil that I use to top off my oil changes for 5 litters. Definitely a little pricy, but it is BMW branded. I'm sure there are products that are comparable at a lower price point.
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Reviewed in the United States on July 13, 2025
★★★★★ 5
Real BMW oil
It’s real. It works.
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Reviewed in the United States on July 23, 2025
★★★★★ 5
Good product
Good product exactly what I normally buy from the dealership. Save me a trip to the dealership and driving 30 minutes. Will definitely buy again.
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Reviewed in the United States on February 23, 2025
★★★★★ 2
Questionable product
Bottle foil seals already opened upon arrival on 3/7 liters of oil. How do I know that what’s in them is what I ordered?
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Reviewed in the United States on April 15, 2026
★★★★★ 5
So easy to fit under your bike
Color: Low profile oil Drain Pan for Motorcycles
Terrific. I use this and I use an oil extractor.
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Reviewed in the United States on April 4, 2026