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Description
Human IgG3 F(c) Mouse mAb (S-460-1)Product Specification Host Mouse Antigen Human IgG3 Synonyms Immunoglobulin heavy constant gamma 3, HDC, Heavy chain disease protein, Ig gamma 3 chain C region, IGHG3 Immunogen Synthetic Peptide Location Secreted, Cell membrane Accession P01860 Clone Number S 460 1 Antibody Type Mouse mAb Isotype IgG2b,k Application ELISA, WB, IHC P Reactivity Hu Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage
Product Specification
| Host | Mouse |
| Antigen | Human IgG3 |
| Synonyms | Immunoglobulin heavy constant gamma 3, HDC, Heavy chain disease protein, Ig gamma-3 chain C region, IGHG3 |
| Immunogen | Synthetic Peptide |
| Location | Secreted, Cell membrane |
| Accession | P01860 |
| Clone Number | S-460-1 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2b,k |
| Application | ELISA, WB, IHC-P |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IHC-P | 1:2000 | null |
Background
The intact antibody of human immunoglobulin (IgG) is composed of the fragment for antigen binding (Fab) and the crystallizable fragment (Fc) for binding of Fcγ receptors. Among the four subclasses of human IgG (IgG1, IgG2, IgG3, IgG4), which differ in their constant regions, particularly in their hinges and CH2 domains, IgG1 has the highest FcγR-binding affinity, followed by IgG3, IgG2, and IgG4 [PMID: 32370812].
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4.7 ★★★★★
Based on 11 reviews
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Product Reviews
★★★★★ 4
Works Great but the price is rising!
Anua Azelaic Acid is a very good serum. Both my daughter and I use it regularly. My daughter has severe rosacea, and this has helped calm her skin significantly her redness is almost gone. For me, it has also made a noticeable difference by reducing redness and giving my skin a healthy glow. We both use it at night, and it’s definitely very soothing and calming. The formula is gentle, lightweight, and works really well for sensitive skin without causing irritation.
However, the only downside is the price, it seems to have increased quite a bit recently, which is concerning. I bought a couple during Amazon Prime Day, which worked out really well. For a relatively simple azelaic acid serum, the price increase feels a bit steep.
If the price continues to rise, I may need to look for a more budget-friendly alternative. Otherwise, it’s a really great serum that delivers great results.
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Reviewed in the United States on March 30, 2026
★★★★★ 5
DERM APPROVED!
I am obsessed with this product!! This feels very luxurious on my skin and does not pill like other products I have had in the past. I have noticed a significant improvement in the background redness in my skin. As someone who works in derm and values good ingredients and products that actually work... I can confidently say that this is the best OTC azelaic acid product I have tried out. It sits very nicely under my moisturizer and does not dehydrate my skin like other azelaic acid products have done in the past. HIGHLY RECOMMEND
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Reviewed in the United States on May 10, 2026
★★★★★ 5
A Game Changer for Sensitive Skin
I use this serum every single day, and it has become one of the most important products in my skincare routine. I have very sensitive skin and cannot tolerate stronger active ingredients such as retinol or high-strength acids, so finding something effective but gentle has been incredibly important.
This serum has helped calm redness, reduce inflammation, and noticeably improve my skin’s overall appearance and comfort. After dealing with a prolonged inflammatory skin condition, this product made a significant difference and helped restore my skin barrier.
The formula feels soothing, hydrating, and non-irritating. If you have sensitive or reactive skin and are looking for a gentle product to help with redness and uneven texture, I highly recommend giving this serum a try.
Photos attached: The green bottle is the product and the second photo includes my favorite additions.
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Reviewed in the United States on May 13, 2026
★★★★★ 5
Perfect for Acne-Prone Skin!
This serum has honestly been a great addition to my routine for redness and post-acne marks. The texture is lightweight, hydrating, and doesn’t feel sticky or heavy on my oily/acne-prone skin.
I have sensitive skin with a focus on barrier protection, and this didn’t irritate my skin at all. It layers beautifully with the rest of my skincare and leaves my skin looking calmer and smoother over time. AND, it doesn’t have a smell!!
Definitely one of my favorite azelaic acid serums I’ve tried.
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Reviewed in the United States on May 18, 2026
★★★★★ 5
6-Month Update: Still a staple for sensitive, acne-prone skin
Size: 3.38 Fl Oz (Pack of 1), Size: 3.38 Fl Oz (Pack of 1)
I originally reviewed this ampoule when I first started using it, and now after about six months of consistent use (morning and night), I feel confident giving a more long-term update.
I have sensitive, acne-prone, combination skin, and this has remained one of the most reliable products in my routine. The texture is still one of my favorite things about it — very lightweight, absorbs quickly, and layers well under moisturizer and sunscreen without pilling.
Over time, I’ve noticed:
Less visible redness
More balanced oil production in my T-zone
Fewer irritation flare-ups when introducing new products
No clogged pores or breakouts from this formula
It doesn’t feel heavy or sticky, even in humid weather. I’ve continued repurchasing and even keep it on subscription because it consistently performs without causing sensitivity.
If you’re looking for a gentle, soothing centella product that works well for long-term barrier support, this has proven to be a dependable option in my experience.
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Reviewed in the United States on December 9, 2025
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