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Description
Phospho-Acetyl-CoA Carboxylase (Ser79) Recombinant Rabbit mAb (S-745-303)Product Specification Host Rabbit Antigen Phospho Acetyl CoA Carboxylase (Ser79) Synonyms Acetyl CoA carboxylase 1; ACC1; Acetyl Coenzyme A carboxylase alpha (ACC alpha); ACAC; ACCA; ACACA Immunogen Synthetic Peptide Location Cytoplasm Accession Q13085 Clone Number S 745 303 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Positive Sample HEK 293 treated with 0. 5 M oligomycin for 30 minutes Predicted Reactivity Bv, Ms, Rt, Sh
Product Specification
| Host | Rabbit |
| Antigen | Phospho-Acetyl-CoA Carboxylase (Ser79) |
| Synonyms | Acetyl-CoA carboxylase 1; ACC1; Acetyl-Coenzyme A carboxylase alpha (ACC-alpha); ACAC; ACCA; ACACA |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | Q13085 |
| Clone Number | S-745-303 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Positive Sample | HEK-293 treated with 0.5 µM oligomycin for 30 minutes |
| Predicted Reactivity | Bv, Ms, Rt, Sh |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| Dot Blot | 1:1000 | |
| WB | 1:1000 | Hu |
Background
Phospho-Acetyl-CoA Carboxylase (Ser79) is a phosphorylated form of Acetyl-CoA Carboxylase (ACC), a key enzyme in lipid metabolism that catalyzes the conversion of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. When phosphorylated at Ser79, ACC is inhibited, preventing the production of malonyl-CoA and thus suppressing fatty acid synthesis. This phosphorylation is primarily regulated by AMP-activated protein kinase (AMPK), which is activated under low energy conditions, such as fasting, to promote fatty acid oxidation and conserve energy. ACC exists in two isoforms, ACC1 and ACC2, with ACC1 mainly involved in fatty acid synthesis and ACC2 regulating fatty acid oxidation by inhibiting carnitine palmitoyltransferase I (CPT-I) in mitochondria. Phospho-ACC (Ser79) antibodies are widely used to detect the phosphorylated state of ACC in various tissues and species, including human, mouse, and rat.
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4.6 ★★★★★
Based on 25 reviews
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Product Reviews
★★★★★ 5
Wonderful
Format: Kindle
The amount of detail in this book is so interesting and the specifics of so much theoretical ideas revolving around true ideas makes it so fun to read. The writer does a great job and describing every situation enough where you get the point but not too much to try to bore you . The book is very easy to follow, keeps you on your toes, was pretty funny to me, and truthfully just a great book for anyone!
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Reviewed in the United States on May 20, 2026
★★★★★ 4
Read it in 2 days
Format: Paperback
This is science based science fiction. How refreshing to read science without turning the story into horror. Without a plethora of characters, it is easy to remember who is who. The story moves along well enough that I wanted to keep going. It us a p age turner in many respects.
All this said, there were too many crises suddenly resolved like some Star Trek episode from 1966. It reached the point where I said to myself, "OK, this doesn't matter. Move along, nothing to see here."
There was good humor, some surprising twists, and enough involvement with characters that I didn't want to put it down.
As science fiction goes, it was good like pulp stories go. It wasn't like Ursula LeGuin or Robert Heinlein but I would probably pick up the next book he writes.
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Reviewed in the United States on May 21, 2026
★★★★★ 5
A book worth rereading
Format: Hardcover
This was a book club pick. Honestly, I wouldn't have chosen to read this myself, but I'm glad that I did. I would have missed out on an incredible story.
I've been reading a lot of thriller and fantasy books lately, that I forgot how much I enjoy sci-fi. This brought it back for me. There's a lot of science-heavy discussions in the book and I loved it! When I got to a subject or term I didn't know, I would go online and learn more about it. I feel that Grace is a dork like me because he wouldn't curse. He had little anecdotes he uses in place of swearing. Something I definitely do myself!
A lot of the book is the MMC talking to himself. Surprisingly, it worked. There's so much humor that it kept the story going. There was not a lull. Usually I dislike info-dumping as an introduction to get all the background story told, but I didn't mind it at all. Maybe I'm being biased because I love science talk.
**SPOILERS AHEAD**
What makes the whole plot engaging is the fact that the plot doesn't seem too fantastical. It's something that could happen. There's a lot of ethics and morals involved in determining what should be done. I would hate to be in a position where I have to chose what's best for everyone. That's why Stratt is a necessary character. I hated some of her decisions and how she operated, but you need someone who's focused on the general welfare of humanity. I would be too focused on myself, my family, etc. As much as it hurts to admit, I'm selfish (and a coward) like Grace. I wouldn't want to die. But was it right for Stratt to force him on the mission? This could also be taken religiously. If God has a plan and things happen for a reason, is it our right to deter what's going to happen? God wiped out the world many times because of humanity's sins, what if this was God's doing? So many questions and debates on right vs wrong, ethics vs morals, and religion vs humanity made for a incredible book club discussion.
I love how this book ended. I wish I could continue reading about Rocky and Grace's adventures, it's that fascinating. However, I think Grace staying on Erid was the best outcome. If the roles were reversed, I don't think Rocky would have the same welcome. I feel that those in charge would have dissected and kept Rocky hostage, all in the name of science. Just as the Astrophage were first introduced, the first things the scientists did was poke and probe. Essentially torturing the Astrophage to see what makes them tick. I think Rocky would have the same fate.
Oh, and my favorite part is the relationship between Rocky and Grace. I cried so many times when I was reading. Scared that something bad was going to happen to either of them. Especially in the scene where Rocky busted out of his tunnel to save Grace. I got upset and told the book that 'if Rocky dies, I swear, this is the worst book ever!' And the scene where Rocky learns about radiation poisoning. How he slowly becomes aware of what happened to his crew, his friends. I was a mess.
This book is definitely one that I could go back and reread.
I did watch the movie afterwards. There's a lot of differences to adapt the story to screen, but it was okay. They got the humor down pat, but I didn't get the direness of the whole situation nor the special bond that both MCs had.
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Reviewed in the United States on April 20, 2026
★★★★★ 5
Excellent story
Format: Kindle
This book is worth your time. It is a great introduction to a variety of scientific disciplines without insulting the reader. It also respects and understands humanity, engineering, history and political science. Then it lays that foundation to tell the story of a unique friendship of two beings with mutual goals who have to communicate and problem solve together. Along the way, you can really contrast how Grace and Rocky do it, vice the Hail Mary team did it.
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Reviewed in the United States on May 22, 2026
★★★★★ 5
A Brilliant, Emotional, and Unforgettable Sci-Fi Adventure
Format: Paperback
Project Hail Mary by Andy Weir is one of those rare novels that delivers everything you could want from science fiction: gripping suspense, fascinating science, humor, heart, and a genuinely moving story about survival and friendship.
The novel follows Ryland Grace, a middle school science teacher who wakes up alone on a spacecraft with no memory of who he is or why he’s there. As his memories slowly return, the stakes become clear: humanity is facing extinction, and he may be the only person who can stop it. The mystery unfolds at a perfect pace, blending high tension with moments of discovery that keep you turning the pages.
What makes this book stand out is how seamlessly it combines hard science with accessibility. Like the author’s earlier work, the scientific details feel authentic and well researched, but they never overwhelm the story. Instead, the problem-solving becomes the engine of the plot. Each obstacle feels real, and the solutions are both clever and satisfying.
The biggest surprise—and the emotional core of the novel—is the relationship that develops during the mission. Without giving anything away, it adds warmth, humor, and depth that elevate the story far beyond a typical survival thriller. By the end, the novel becomes less about science and more about courage, trust, and the willingness to sacrifice for others.
The pacing is excellent throughout, with a balance of suspense, humor, and heartfelt moments. If there’s a small drawback, it’s that some plot developments feel a bit convenient. But the strong characters and emotional payoff more than make up for it.
Overall, this is a must-read for fans of science fiction, space exploration, and anyone who enjoys smart, character-driven storytelling. It’s thrilling, funny, deeply human, and surprisingly emotional. I finished it feeling both entertained and uplifted. Highly recommended.
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Reviewed in the United States on February 19, 2026