SKU: 51792672468

TrkB His Tag Protein, Human

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Description

TrkB His Tag Protein, HumanProduct Specification Species Human Antigen TrkB Synonyms NTRK2 Accession Q16620 1 Amino Acid Sequence Cys32 His430, with C terminal 8*His

Product Specification


Species Human
Antigen TrkB
Synonyms NTRK2
Accession Q16620-1
Amino Acid Sequence

Cys32-His430, with C-terminal 8*His CPTSCKCSASRIWCSDPSPGIVAFPRLEPNSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPSTDVTDKTGREHGGGSHHHHHHHH

Expression System HEK293
Molecular Weight 70-85kDa (Reducing)
Purity

>95% by SDS-PAGE

Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

Background

TrkB gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signaling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. Neurotrophic tyrosine kinase receptor type 2 (NTRK2) is also known as BDNF/NT-3 growth factors receptor, Tropomyosin-related kinase B (TRKB) and TrkB tyrosine kinase, which belongs to the protein kinase superfamily or Tyr protein kinase family. Insulin receptor subfamily. NTRK2/TrkB contains two Ig-like C2-type (immunoglobulin-like) domains, two LRR (leucine-rich) repeats, one LRRCT domain, one LRRNT domain, one protein kinase domain. NTRK2/TrkB involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity.

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Exchange/Return Notes
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SKU: 51792672468

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4.8 ★★★★★
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Wilderness Family
Boise, US
★★★★★ 5
Mechanic Recommends Sea Foam -- Best Gas Treatment for All Engines
Color: Pack of 1
We have a small-engine mechanic who turned us onto SeaFoam motor treatment -- and against most gasoline preservatives and treatments. He said he'd drained, or seen inside, thousands of gasoline tanks, and the stuff sold as gasoline storage additives was often still there, sitting as gel on the bottom of the tank. Just gunk. He also said most brands of engine treatment weren't worth the money. However, he swore by SeaFoam, which I'd never tried at the time, and my experience since has proved him out. I've had many rough-running engines find their power and performance again, with nothing different, but a shot of SeaFoam in the gas tank (and the crankcase). We own a number of vehicles and equipment with small engines, from a compact backhoe, to a ride'em Husqvarna mower, weedwacker, chainsaw -- and on the larger size, a Honda SUV and Ford F150 pickup. All of them have benefited greatly from the regular use of SeaFoam. However, when we're running the road vehicles a lot, especially in the summer, we go through gas and don't necessarily add SeaFoam with every fill. Recently, the Ford began to run rough. It stalled as I pulled up to corners and lights. In the past, that would have meant a mechanic and an expensive tune-up. All I did was go for a fill-up, and started by adding a full can of SeaFoam. Problem solved, just like that. The Terramite (made in the USA) backhoe is not used a lot -- and as with most motors, that is a problem. It's bad for an engine not to run it -- and especially, in most cases, for it to sit with gas in the tank. The backhoe has a Kohler Command 25-horse gasoline engine that powers the hydraulics that run the wheels, steering, front-loader, and backhoe. I change the spark plugs each season, but it, like my Stihl chainsaw, and 6500 watt backup (gasoline) generator, and for that matter, all the small engines, can be hard to start after a hiatus. And even when they get going, they'll run rough. I used to drain the tanks frequently, then run them dry, then fill again before use, and hope for the best. But SeaFoam has changed all that. Throughout the summer, I can leave treated gas in the tank, and have little problems with starts or rough running. In the smaller equipment, I dose the gasoline with each fill (1 oz per gallon), as SeaFoam cleans both carburetors and full injection systems. It is good for gasoline and diesel engines. Added to your crankcase (1.5 oz per quart of oil), it cleans deposits and quiets noisy lifters. These days, most gasoline is mixed with ethanol and that's a bad thing for small engines. Ethanol goes hand in hand with water -- and as we all know, water in the gas is anathema to motors. Again, my small engine mechanic told me, 90% of the no-start problems he had to deal with were caused by ethanol-caused water in the fuel system. SeaFoam actually controls moisture and prevents this problem. It also de-ices and is anti-gel. In my opinion, when it comes to gasoline and diesel engines, large and small, SeaFoam is THE Silver Bullet. My equipment is often running, while my neighbors are running with theirs to the shop. I've told many about SeaFoam, but some people seem to want to do it the hard way. By the way, I also swear by PRI-G fuel additive for long-term gasoline storage. I keep 100 gallons of gas in tanks for emergency use. We are in a rural, wilderness area. I was introduced to that by survival expert, Steve Harris. He said he's had gasoline that was 10 years old still run equipment, because he'd added PRI-G to it (you can buy here on Amazon). Of course, you have to remember to add more PRI-G each year -- that's the catch. So our rule of thumb is, PRI-G for long term fuel storage -- and SeaFoam for month to month. Also -- this price is right! Of course, when you compare the cost of equipment breakdown, and having to take anything to a mechanic, this is almost free. However, apples to apples, this price is cheaper than Walmart -- and up to $4 cheaper per can than many auto supply and hardware stores. Can't say enough good things about this product! Highly recommended.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 19, 2015
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Verified Purchase
Rebecca Lovegrove
Alexandria, US
★★★★★ 5
I swear by Seafoam, especially for small engines
Color: 3 Pack
I swear by Seafoam. It has really helped out my small engines, especially the 2 strokes and ones that sit around for long periods of time like my leaf blower and roto tiller. After I started adding Seafoam every time I get fuel I have had zero starting issues. They can sit all year and they will still start right up. In my car/trucks with higher miles I've used it to clean out the crankcase with great results. I add a can to the oil right before doing an oil change. I add a can then take a short drive(10 miles) to make sure the oil is up to operating temperature and change the oil once I get home. It does a good job cleaning any sludge out of the pan and the new oil stays looking fresh/clean way longer.
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Reviewed in the United States on May 4, 2026
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B. Bordelon
Phoenix, US
★★★★★ 5
It's Sea Foam (but not green)
Color: 3 Pack
What is there to say? If you're buying Sea Foam, you know what it is and what it does, and you're probably going to continue buying it. It's great stuff.
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Reviewed in the United States on April 21, 2026
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Gary0529
Omaha, US
★★★★★ 5
It works!
Size: 16 Fl Oz (Pack of 1), Style: Individual
A short story long---LOL---My zero turn started acting quirky-it would not run at full power and would begin to stall when put under a full load - like trying to mow some taller or thicker grass- never did stall since I would immediately kill the mower but obviously it was not right. I checked and changed the fuel filters-this one has 2 . One in the pick up line in the tank and one is inline just before the fuel pump unit. No help! So, before I dropped the big bucks to have the local farm dealer come and pick it up (at $75 per pickup and return) plus h=whatever shop charges that would result I thought "What the heck, lets give this stuff a try" I gambled $6 . I put in 5 ounces for the 5 gallons tank, and filled it with the gas I had on hand- should have been relatively fresh gas -no more than 2 weeks since pumped . Well, whatever the cause of the issue within about 15 to 30 minutes of low speed running- mostly at idle - the engine seemed to be idling smoothly as opposed to before where it surged but never died, I gave it a try at mowing. YEA!!!! full power and no bogging down - I finished mowing the yard and a part of the pasture (not yet grown up much so it is not requiring the rotary cutter YET) My only guess is perhaps a batch of either old gas or some water in the gas can or mower tank but whatever the cause it fixed it --and all for $6.
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Reviewed in the United States on April 12, 2025
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Nancy McKenzie
Dallas, US
★★★★★ 5
Convenient to order from Amazon
Size: 16 Fl Oz (Pack of 1), Style: Individual
Works as expected.
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Reviewed in the United States on January 25, 2026

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