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Ships within 48 hours · Estimated delivery Jul 9 - Jul 14
For Your Every Summer RSVP, with Code: SUMMER15
Description
IGF2BP2 Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen IGF2BP2 Synonyms Insulin like growth factor 2 mRNA binding protein 2; IGF2 mRNA binding protein 2; IMP 2; Hepatocellular carcinoma autoantigen p62; IGF II mRNA binding protein 2; VICKZ family member 2; IMP2; VICKZ2 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession Q9Y6M1 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P, ICC Reactivity Hu, Mk Positive Sample HepG2, 293T, A204
Product Specification
| Host | Rabbit |
| Antigen | IGF2BP2 |
| Synonyms | Insulin-like growth factor 2 mRNA-binding protein 2; IGF2 mRNA-binding protein 2; IMP-2; Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; VICKZ family member 2; IMP2; VICKZ2 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus |
| Accession | Q9Y6M1 |
| Antibody Type | Polyclonal antibody |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Mk |
| Positive Sample | HepG2, 293T, A204 |
| Purification | Immunogen Affinity |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
| IHC-P | 1:50 | Hu |
| ICC | 1:500 | Hu |
Background
IGF2BP2 (Insulin-like growth factor 2 mRNA-binding protein 2) is an m⁶A-reader RNA-binding protein that stabilizes oncogenic transcripts, thereby driving tumor growth, metastasis, metabolic reprogramming and resistance to ferroptosis, autophagy and therapy across cancers including prostate, breast and pancreatic by enhancing mRNA stability of targets such as AR-V7, SNRPD1 and SLC1A5.
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