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Description
Biotinylated Fc γ RIV/CD16-2 His&Avi Tag Protein, MouseProduct Specification Species Mouse Synonyms Fc gamma RIV, CD16 2, Fcgr4 Accession A0A0B4J1G0 Amino Acid Sequence Gly21 Gln203, with C terminal 8*His&Avi tag GLQKAVVNLDPKWVRVLEEDSVTLRCQGTFSPEDNSIKWFHNESLIPHQDANYVIQSARVKDSGMYRCQTALSTISDPVQLEVHMGWLLLQTTKWLFQEGDPIHLRCHSWQNRPVRKVTYLQNGKGKKYFHENSELLIPKATHNDSGSYFCRGLIGHNNKSSASFRISLGDPGSPSMFPPWHQ GGGSGGGSHHHHHHHHGLNDIFEAQKIEWHE Expression System HEK293 Molecular Weight 28 35kDa Purity >95% by SDS PAGE
Product Specification
| Species | Mouse |
| Synonyms | Fc gamma RIV, CD16-2, Fcgr4 |
| Accession | A0A0B4J1G0 |
| Amino Acid Sequence | Gly21-Gln203, with C-terminal 8*His&Avi tag GLQKAVVNLDPKWVRVLEEDSVTLRCQGTFSPEDNSIKWFHNESLIPHQDANYVIQSARVKDSGMYRCQTALSTISDPVQLEVHMGWLLLQTTKWLFQEGDPIHLRCHSWQNRPVRKVTYLQNGKGKKYFHENSELLIPKATHNDSGSYFCRGLIGHNNKSSASFRISLGDPGSPSMFPPWHQ GGGSGGGSHHHHHHHHGLNDIFEAQKIEWHE |
| Expression System | HEK293 |
| Molecular Weight | 28-35kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Hirano M. et al. (2007) IgEb immune complexes activate macrophages through FcγRIV binding. Nature Immunology. 8: 762-771. |
Background
Fc γ RIV (Low affinity immunoglobulin gamma Fc region receptor IV), also known as CD16-2 (Fc γ RIV), belongs to the Fc γ receptor family. There are three types of Fc γ receptors: Fc γ RI (CD64), Fc γ RII (CD32) and Fc γ RIII (CD16). Fc γ RI (CD64) has a high affinity for IgG monomer, while Fc γ RII (CD32) and FC γ RIII (CD16) have a relatively low affinity for IgG. Human CD16 is encoded by two genes, Fc γ RIIIA and Fc γ RIIIB. The gene sequence of CD16-2 is more similar to that of human Fc γ RIIIA protein. The combination of FcγRIV and IgG2a can promote bone cell differentiation. The combination of FcγRIV and IgE can promotes macrophage-mediated phagocytosis, antigen presentation, and proinflammatory cytokine production.
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4.5 ★★★★★
Based on 16 reviews
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Product Reviews
★★★★★ 5
Excellent children's book!
Format: Hardcover
Greg Pizzoli's wonderful book, The Watermelon Seed, is a delight for children and adults alike! The whimsical illustrations he creates, keep children glued to each page. It is fun and enjoyable to read over and over again with a child that just has to have it read every single night to them. The story is sweet, simple and meaningful. Whether you are looking for a book for your child, another child or the child in yourself-dive right in. This one is terrific!
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Reviewed in the United States on December 17, 2018
★★★★★ 4
Cute but
Format: Hardcover
Caution that some children may be alarmed by the crocodile swallowing the watermelon seed. Know your audience. Otherwise a very cute, silly story that is great for a summer read or watermelon theme lesson.
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Reviewed in the United States on August 25, 2023
★★★★★ 5
Great graphics
Format: Paperback
Discovering this children's book has been a true delight. The vivid illustrations and enthralling storyline have made it an immediate favorite for my little one. What truly stands out is its clever approach to conveying essential life lessons. Now, it's an eagerly anticipated part of our nightly reading routine—a definite must-read for young readers!
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Reviewed in the United States on August 15, 2023
★★★★★ 5
Nice book
Format: Paperback
Bought for a friends baby. nice book.
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Reviewed in the United States on August 14, 2025
★★★★★ 5
Great book, great quality and she loves it!
Format: Paperback
My little girl loves this book.
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Reviewed in the United States on July 19, 2025