SKU: 25552881680

Rat IgA OneStep ELISA Kit

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Description

Rat IgA OneStep ELISA KitProduct Specification Antigen IgA Immunogen Recombinant Protein Antibody Type Recombinant mAb Reactivity Rt Purification Protein A Stability & Storage 2 to 8 C as supplied. Kit Precision Intra assay: 5. 7% Inter assay: 7. 1% Sample type Cell culture supernatant, Serum, Plasm Assay type Sandwich (quantitative) Sensitivity 0. 043 ng ml Range 1. 56 ng mL 100ng mL Recovery Cell culture supernatant: 99% Serum: 90% Plasm: 115% Assay time 60 minutes Species

Product Specification


Antigen IgA
Immunogen Recombinant Protein
Antibody Type Recombinant mAb
Reactivity Rt
Purification Protein A
Stability & Storage 2 to 8 °C as supplied.

Kit


Precision Intra-assay: 5.7%;
Inter-assay: 7.1%
Sample type Cell culture supernatant, Serum, Plasm
Assay type Sandwich (quantitative)
Sensitivity 0.043 ng/ml
Range 1.56 ng/mL – 100ng/mL
Recovery Cell culture supernatant: 99%
Serum: 90%
Plasm: 115%
Assay time 60 minutes
Species reactivity Rat

Background

Immunoglobulin A (IgA) is a pivotal antibody isotype central to mucosal immunity and systemic immune regulation in rats. Structurally, rat IgA exists predominantly as a monomer in serum and as a dimer or polymer (secretory IgA, sIgA) at mucosal surfaces. Each IgA molecule comprises two α-heavy chains and two light chains (κ or λ), forming a flexible Y-shaped structure stabilized by disulfide bonds. The α-heavy chain contains three constant domains (Cα1–Cα3), with the Fc region (Cα2–Cα3) facilitating interactions with the Fcα receptor (FcαRI) and the polymeric immunoglobulin receptor (pIgR). Secretory IgA incorporates a J-chain and a secretory component, which enhance its stability in protease-rich mucosal environments. Extensive glycosylation of rat IgA further modulates its solubility, receptor binding, and resistance to enzymatic degradation. Rat IgA is the primary antibody safeguarding mucosal surfaces (e.g., respiratory, gastrointestinal tracts), where it neutralizes pathogens, blocks microbial adhesion, and maintains commensal microbiota balance. Secretory IgA mediates immune exclusion by trapping pathogens in mucus for mechanical clearance, while serum IgA contributes to systemic immune homeostasis by regulating inflammatory responses via FcαRI signaling. Additionally, rat IgA may engage in eosinophil-mediated antiparasitic defense and modulate allergic or autoimmune reactions through interactions with immune cells. Rat IgA shares conserved structural motifs with murine and human IgA, particularly in the α-chain constant domains. However, species-specific variations in glycosylation patterns, J-chain assembly, and secretory component binding necessitate species-specific assays for accurate detection. For example, rat IgA lacks the extended hinge region characteristic of human IgA1, resulting in distinct antigen accessibility and protease resistance. Clinical and Experimental Significance of IgA Levels: Elevated IgA: Associated with chronic mucosal infections (e.g., intestinal pathogens), autoimmune disorders (e.g., experimental colitis models), or inflammatory conditions. Reduced IgA: May indicate primary immunodeficiency (e.g., selective IgA deficiency in genetically modified models), immunosuppressive therapies, or gut dysbiosis. Applications of the Rat IgA ELISA Kit: This OneStep Rat IgA ELISA kit is designed for rapid and precise quantification of IgA in serum, plasma, or cell culture supernatants. Advantages of this OneStep ELISA Kit Design: Simplified Workflow: Combines sample incubation and detection in a single step, eliminating intermediate washing and reducing hands-on time. High Efficiency: Achieves results within 1 hours, ideal for high-throughput studies or urgent diagnostics. Enhanced Precision: Minimizes procedural variability and cross-contamination risks through optimized reagent formulation. Broad Compatibility: Validated for diverse biological matrices, ensuring flexibility in experimental design. This kit’s streamlined protocol and robust performance make it an indispensable tool for researchers and clinicians seeking reliable IgA quantification in time-sensitive or resource-limited settings.

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SKU: 25552881680

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David
Boise, US
★★★★★ 5
Good Product
Size: One Size, Color: Black/Silver Reflective/3
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Reviewed in the United States on May 15, 2024
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Jong Chon
West Palm Beach, US
★★★★★ 5
Perfect Lightweight Sun Visor for Active Days
Size: One Size, Color: Black/Silver Reflective/3
I’m so impressed with the adidas Superlite Sun Visor—it’s become my go-to for all my outdoor activities. The lightweight design makes it incredibly comfortable to wear for hours without feeling any pressure on my head. I love how the black with silver reflective detailing gives it a sleek, sporty look while also adding visibility in low light. The moisture-wicking fabric keeps sweat away, so I stay cool and dry even during intense workouts or long walks in the sun. The adjustable strap ensures a perfect fit every time, and it stays securely in place without slipping. It provides great sun protection for my face and eyes without making me feel overheated like a full cap sometimes can. Whether I’m playing tennis, golfing, running, or just out for a casual day, it performs beautifully. The quality is outstanding, and it holds up perfectly after many uses. This visor is stylish, functional, and a must-have for anyone who spends time outdoors.
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Reviewed in the United States on August 13, 2025
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begro
Fort Morgan, US
★★★★★ 5
Gorgeous charcoal color
Size: One Size, Color: Black/Silver Reflective/3
Lightweight and perfect for indoor or outdoor use: at the pool, beach, lake, gym, trail, yard work or watching outdoor sporting events. Another plus: the band soaks up my sweat and keeps my eyes and contacts free of “runoff” while the size of the bill is just big enough to shade my face. Also, it isn’t bulky, fitting perfectly under my bike helmet. This is a bonus that provides a smooth transition from bike trail to bike brewery! No more wasted time making myself look presentable. When the humidity is high, this also functions as a bad hair banisher in any scenario. However, the feature I find most useful is the Velcro strap to make adjustments to your head and hairstyle. Yeah it can grab your hair if not careful but also I don’t need to adjust it like I did with another comparable brand. It’s a trade off I’m willing to make. I already own one from years and years ago. Quality is still a good as it ever was. I’m glad I ordered the charcoal with rose gold logo-the color combo is just what I was looking for to update my basic black one. The logo has a slight metallic sheen, definitely not matte but also not glitter city. It’s perfectly priced for the quality, style and fit. Very happy with my purchase.
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Reviewed in the United States on July 9, 2022
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rcanw
Chelsea, US
★★★★★ 5
I love Adidas visors great fit!
Size: One Size, Color: Ray Blue/White/3
Every time I buy an Adidas visor I am in love. They fit pefectly on my smaller type head but they adjust to I assume a large woman. I love the feel, the light weight, the brim is perfect length and the size just works for me. I use them for golf. This color is not quite cobalt and not quite royal. More of a cerulean blue. Very pretty and it goes great with my golf attire. I am embarrassed to say I own 10 Adidas visors.. Wish they made yellow.
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Reviewed in the United States on May 17, 2026
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dbeck
Cuba, US
★★★★★ 4
Nice visor
Size: One Size, Color: Grey Six/Rose Gold/3
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Reviewed in the United States on May 4, 2026

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