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Description
Phospho-EphA3 (Tyr779) Recombinant Rabbit mAb (S-3551)Product Specification Host Rabbit Antigen Phospho EphA3 (Tyr779) Synonyms Ephrin type A receptor 3; EPH like kinase 4 (EK4; hEK4); HEK (Human embryo kinase); Tyrosine protein kinase TYRO4; Tyrosine protein kinase receptor ETK1 (Eph like tyrosine kinase 1); ETK; ETK1; HEK; TYRO4; EPHA3 Location Secreted, Cell membrane Accession P29320 Clone Number S 3551 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Purification Protein A
Product Specification
| Host | Rabbit |
| Antigen | Phospho-EphA3 (Tyr779) |
| Synonyms | Ephrin type-A receptor 3; EPH-like kinase 4 (EK4; hEK4); HEK (Human embryo kinase); Tyrosine-protein kinase TYRO4; Tyrosine-protein kinase receptor ETK1 (Eph-like tyrosine kinase 1); ETK; ETK1; HEK; TYRO4; EPHA3 |
| Location | Secreted, Cell membrane |
| Accession | P29320 |
| Clone Number | S-3551 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
Background
Phospho-EphA3 (Tyr779) is the ligand-triggered, autophosphorylated form of the receptor tyrosine kinase EphA3 that localizes within the kinase domain; its phosphorylation is essential for full receptor activation, creates a docking site for the SH2-domain adaptor CrkII, and thereby couples EphA3 to downstream RhoA/ROCK signaling to regulate actomyosin dynamics, cell adhesion, migration and neurite retraction.
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