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Description
Lipocalin-2/NGAL Recombinant Rabbit mAb (S-2280-129)Product Specification Host Rabbit Antigen Lipocalin 2 NGAL Synonyms Neutrophil gelatinase associated lipocalin; Lipocalin 2; Oncogene 24p3 (24p3); SV 40 induced 24p3 protein; Siderocalin LCN2; p25; Lcn2 Immunogen Synthetic Peptide Location Secreted Accession P11672 Clone Number S 2280 129 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Ms, Rt Positive Sample mouse spleen, mouse bone marrow, mouse lung, rat spleen ,rat liver
Product Specification
| Host | Rabbit |
| Antigen | Lipocalin-2/NGAL |
| Synonyms | Neutrophil gelatinase-associated lipocalin; Lipocalin-2; Oncogene 24p3 (24p3); SV-40-induced 24p3 protein; Siderocalin LCN2; p25; Lcn2 |
| Immunogen | Synthetic Peptide |
| Location | Secreted |
| Accession | P11672 |
| Clone Number | S-2280-129 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Ms, Rt |
| Positive Sample | mouse spleen, mouse bone marrow, mouse lung, rat spleen ,rat liver |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Ms, Rt |
| IHC-P | 1:2000 | Ms, Rt |
Background
Lipocalin-2/NGAL is a 25-kDa secreted glycoprotein of the lipocalin superfamily that forms an 8-stranded β-barrel calyx able to bind and transport ferric siderophore complexes, thereby acting as a bacteriostatic innate immune factor that starves bacteria of iron while simultaneously delivering iron to mammalian cells via the megalin/24p3R receptor, and is rapidly induced by inflammatory, hypoxic or nephrotoxic stress in neutrophils, macrophages and epithelia, circulates as monomer, homodimer or MMP-9–linked heterodimer, functions as a sensitive biomarker of acute and chronic kidney injury, modulates cell survival, differentiation, epithelial-to-mesenchymal transition and oncogenesis, and is transcriptionally up-regulated through NF-κB, ERK and JAK-STAT pathways in metabolic disorders such as obesity and insulin resistance.
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4.3 ★★★★★
Based on 2225 reviews
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Product Reviews
★★★★★ 5
A Beta’s Dream!
Format: Kindle
I loved this book!!
Unwanted follows Cammie, a single mom and Beta, working two jobs, trying her best to raise a son and daughter since her a$$hole ex Alpha kicked them out after meeting his scent match.
Being a Beta from the wrong side of the tracks, Cammie is often the victim of rumors and blatant disrespect from several alphas in town; and while in a panic searching for her daughter who somehow managed to wander outside of the home, she finds herself in a panic when she comes across a police officer. Rather than help her, Cammie finds herself feeling threatened and helpless against the alpha’s behavior.
That’s when Reid, one of her Alpha neighbors (and super hot firefighter) swoops in to her rescue. Sparks fly, but Cammie thinks nothing of it since she is so used to being disregarded. Little does she know, Reid goes home to his Omega, the adorable and caring Finn, and confesses that he thinks he’s met their match.
What follows is a beautiful hurt/comfort romance, with lots of steam, and found family perfection! Reid and Finn worship Cammie and absolutely adore her kids. They’ll do anything to protect them and cherish them, to erase all the hurt and rejection that their bio dad put them through. It’s such a heart warming and emotional story—perfect for when you’re feeling like something low angst with princess treatment for not just Cammie, but her kids as well.
I definitely recommend picking this one up!!
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Reviewed in the United States on June 28, 2024
★★★★★ 5
Emotional read with children
Format: Kindle
Cammie is a single mother of two children whose ex-boyfriend, who is an alpha that he met his scent matched omega and dumped her via messenger on his phone then the next day put their house up for sale. Cammie moves back to her hometown, but because she has no support, is working two jobs to keep her and the children in a small rented house. One night her four year gets out of the house and she meets a neighbour, but she refuses to make the same mistake again by getting involved with another alpha, but Reid is convinced they are scent matched mates even though Cammie is a beta. Reid and his omega Fin start to court Cammie and her two children that they belong together as a pack and family. Cammie's ten year old son is a tough one to convince, but the scenes between him and Reid and Fin, they were so good. I was tearing up at times, found family was a big theme and I really liked this book. I highly recommend that you try it too.
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Reviewed in the United States on February 16, 2025
★★★★★ 5
Good start to a series
Format: Kindle
I delayed reading the series for reasons I don’t remember. But my TBR list is huge so I thought I’d take a shot of this and I was pleasantly surprised. I didn’t think the blurb about it was anything special. But it was a very good book. It took some interesting twists and turns. I am so glad the second book is already out. Because I would not have waited patiently. Very slow burn but good storyline. 🔥🔥/5
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Reviewed in the United States on January 3, 2025
★★★★★ 4
A good read
Format: Kindle
Multiple points of view. 3 Alpha men and an Omega male. She is a Beta in training for a new program placing betas in Alpha/Omega packs. Mila is only doing the program for the money to take care of her dad. She wasn't expecting to fall for a pack but when she sees this packs Omega she is done for. There is just something about him. His Alphas are good looking as well. Too bad she is hiding a secret and their government is acting shady. I liked it and can't wait to see where their story goes.
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Reviewed in the United States on November 14, 2023
★★★★★ 3
Slightly repetitive but I did love some things
Format: Kindle
I love this type of story. And omegaverse is one of my all time favorite genres. But there are a few things that pulled me out of my enjoyment while I was reading. It was repetitive at times as well as struggled with telling not showing. So we didn’t always feel like we were experiencing things with the main character. There were also some plot holes but they may still be answered in part 2.
Now this isn’t to be said I didn’t enjoy parts of the story. I loved the almost instant love between Mila and Oliver. And how he started changing around her.
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Reviewed in the United States on February 15, 2024
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