SKU: 93097838009

LONP1 Rabbit Polyclonal Antibody

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Description

LONP1 Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen LONP1 Synonyms Lon protease homolog, mitochondrial; LONHs; Lon protease like protein (LONP); Mitochondrial ATP dependent protease Lon; Serine protease 15; PRSS15 Immunogen Synthetic Peptide Location Mitochondrion Accession P36776 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Positive Sample HEK 293, HeLa, SH SY5Y, Jurkat, NIH 3T3, C6 Predicted Reactivity Bv

Product Specification


Host Rabbit
Antigen LONP1
Synonyms Lon protease homolog, mitochondrial; LONHs; Lon protease-like protein (LONP); Mitochondrial ATP-dependent protease Lon; Serine protease 15; PRSS15
Immunogen Synthetic Peptide
Location Mitochondrion
Accession P36776
Antibody Type Polyclonal antibody
Isotype IgG
Application WB, IHC-P
Reactivity Hu, Ms, Rt
Positive Sample HEK-293, HeLa, SH-SY5Y, Jurkat, NIH/3T3, C6
Predicted Reactivity Bv
Purification Immunogen Affinity
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu, Ms, Rt
IHC-P 1:500 Hu, Ms, Rt

Background

LONP1 protein, also known as Lon protease homolog 1, is a nuclear-encoded mitochondrial AAA+ serine protease that plays a crucial role in maintaining mitochondrial homeostasis. It is highly conserved across species and is composed of three functional domains: an N-terminal domain for substrate recognition, an AAA+ domain for ATP binding and hydrolysis, and a protease domain for protein degradation. LONP1 forms a hexameric complex in the mitochondrial matrix and is responsible for degrading misfolded, oxidized, and damaged proteins to prevent their accumulation and maintain mitochondrial proteostasis. Additionally, LONP1 has chaperone-like functions in protein folding and assembly, and it regulates mitochondrial DNA (mtDNA) replication and transcription by interacting with mitochondrial transcription factor A (TFAM). Its dysfunction is associated with various diseases, including mitochondrial disorders and cancer, making it a potential target for therapeutic interventions.

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SKU: 93097838009

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shiko
Draper, US
★★★★★ 5
Legit Product.
Color: Style A:Pink
Looks like the image. Works well.
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Reviewed in the United States on April 7, 2026
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Richard Gonzalez
Houston, US
★★★★★ 5
Great item!
Color: Style A:Pink
Excellent item, easy to install
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Reviewed in the United States on May 24, 2026
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George T.
Belleville, US
★★★★★ 5
Works fine for me
Color: Style A:Pink
Everything worked as it should really happy with the fact that it came with a few sticky back tie downs to help keep the cable from swinging around. I'm hoping this one will last longer than my last one. ( Purchased from a different distributor.)
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Reviewed in the United States on May 27, 2026
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Lee Bellegarde
Whiting, US
★★★★★ 1
It works, but wiring is bad
Color: Style A:Pink
It works, but is just another one that is an exposed main board that lights up. Edit: it recently had a wiring issue. I will have to buy another kind. These aren't working for me at all.
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Reviewed in the United States on May 16, 2026
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Sharis Howard
Omaha, US
★★★★★ 1
have to fuss with it for the razors on both sides to go
broke on me within first use i had to keep refixing each side because it would randomly stop working, fully charged, just to get it to work for three secinds just to have to fix it again.
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Reviewed in the United States on June 2, 2026

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