SKU: 87097093269

Hista Clear - DAO Enzyme (60 tablets)

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Description

Hista Clear - DAO Enzyme (60 tablets)NEW: Now in NEW packaging Conners Clinic Originals Hista Clear is a patented enzyme formula containing diamine oxidase (DAO) the main enzyme responsible for the degradation of ingested histamine. This enzyme has been clinically tested and found to break down food derived histamine in the digestive tract. Our bodies are complex, and there is usually more at play than we think. What most dont take into consideration when addressing histamine related

NEW: Now in NEW packaging

Conners Clinic Originals Hista Clear is a patented enzyme formula containing diamine oxidase (DAO) - the main enzyme responsible for the degradation of ingested histamine.  This enzyme has been clinically tested and found to break down food-derived histamine in the digestive tract.  

Our bodies are complex, and there is usually more at play than we think. What most don’t take into consideration when addressing histamine-related health issues is genetics. Whether you’re on a low histamine diet due to histamine intolerance, or simply trying to reduce high histamine foods for general health, you will benefit from understanding how your genes are related. Learn more about histamine and genetics here!

Our body has two distinct methods of clearing things that could bring it harm: our immune system kills living toxins (bacteria, virus, parasites…) and our detoxification pathways clear non-living toxins (chemicals, heavy metals, drugs…). We have one other system that sits somewhere in the middle between the immune and the detoxification systems that helps with both: the mast cells. Read more about Histamine’s Double-edge Sword in the Formation and Progression of Cancer.

 

Clinical Applications
  • Supports Healthy Degradation of Food-Derived Histamine*
  • Enhances the Presence of Diamine Oxidase in the Digestive Tract*
Description:


Hista Clear provides a concentrated source of diamine oxidase (DAO)—the main enzyme responsible for the degradation of ingested histamine. This formula delivers the clinically researched dose of DAO in an easy-to-swallow, gastro-resistant mini-tablet, which is essential for releasing DAO in the small intestine, where it breaks down food-derived histamine. HistDAO does not manage or address antibody-related or IgE-related food allergies.*

Discussion:

Histamine is a bioactive or “vasoactive” amine produced in the body in response to an injury or foreign substance. It has an array of physiological effects, including increasing blood supply to specific sites in the body. In addition, histamine is involved in the immune response, regulation of gastric acid, permeability of blood vessels, contraction of muscles, and the normal response to inflammation.[1] The highest concentrations of histamine in the body are found in the gastrointestinal tract, lungs, and skin, with lesser amounts in the brain and heart.*

Histamine is not only produced in the body but is also present in many fermented foods, such as sauerkraut, sausage, cheese, yogurt, and alcoholic beverages. Tuna, olives, spinach, eggplant, avocados, tomatoes, cherries, and citrus fruits are other histamine-containing foods. Despite their absence of histamine, some foods, such as berries, tea, and a variety of spices, stimulate the endogenous production of the amine due to their benzoate content. In addition, microbial fermentation can convert the histidine in high-protein foods to histamine so that the histamine content of food can increase over time.*[1]

Endogenous and exogenous histamine must be broken down in order to maintain homeostasis and histamine balance. The enzyme diamine oxidase (DAO) degrades histamine by converting it from 2-(4-imidazolyl)- ethylamine to the inactive metabolite imidazole acetaldehyde.[2] The active ingredient in HistaClear is porcine-derived diamine oxidase, and research suggests that DAO derived from porcine kidney appears to have identical action to DAO derived from porcine intestine.[3] In humans and other mammals, DAO is found in high concentrations in the gastrointestinal mucosa. Animal studies suggest that circulating DAO may be a marker for mucosal integrity and maturity.[4] Certain drugs may affect histamine balance in the body by promoting histamine release or inhibiting DAO.*[2]

Histamine tolerance may not be the same for everyone. Results of a double-blind, placebo-controlled crossover study suggest that tolerance to histamine can vary from individual to individual.[5] Total body histamine load must be considered when evaluating histamine tolerance, and a balance between histamine and DAO appears to be crucial to maintaining skin, rhinoconjunctival, and gastrointestinal health.[2,6] Genetic and environmental factors may interact to influence DAO expression. Ongoing research addresses the role that genetic variations may play in individual differences in DAO metabolism, and serum activity was significantly associated with seven single nucleotide variations within the DAO gene.[7,8] Histamine tolerance may be reflected in detailed questionnaires, food intake logs, trial with low-histamine diet, and measurement of DAO and histamine.*[9,10]

Histamine tolerance and its manifestation may vary from organ to organ as well. A study of 39 patients suggested that intake of DAO produced a statistically significant reduction in symptoms associated with exogenous histamine ingestion, although single symptoms were not found to be reproducible.*[11]

Ultimately, diminished serum DAO levels appear to be associated with changes in histamine degradation and serum histamine levels.[10] Although the mechanism of histamine degradation is uniform throughout the body, HistaClear only addresses excess exogenous histamine found in the folds, villi, and microvilli of the small intestine. HistaClear is not absorbed and therefore does not have systemic activity. A two-capsule dose of HistaClear contains 20 mg of vitamin C and 20,000 HDU (histamine degrading units) from diamine oxidase. HistaClear is NOT EFFECTIVE for symptoms of immune- related food allergies, such as peanuts, shellfish, etc.*

Read our article: Low Histamine Diet: The High Histamine Foods List

Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.

Video:


Directions:

Take 1-2 capsules no more than 15 minutes before the consumption of histamine-rich foods, or take as directed by your healthcare practitioner.

Cautions:

Consult your healthcare practitioner before use, especially if you are pregnant or nursing. Keep out of reach of children. Avoid if allergic to pork or any other ingredient. HistaClear is NOT EFFECTIVE for symptoms of immune- related food allergies, such as peanuts, shellfish, etc.


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Los Angeles, US
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Super helfpul in the summer
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Coolest wireless charger design I've seen
I just gotta say that this is the coolest design for a wireless charger, looks kinda futuristic. Now how well does this work? Amazingly well and truly easy to use. It is adjustable, stable and much safer for everyone. I really like this charger.
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Louisville, US
★★★★★ 3
Wow that light color ring is annoying
There is no way to turn this color light off. I don't even know why it has to have a light at all. I suppose it is to tell you it has power. But the light could have been something that momentarily turns on and then off as you place the phone on. I'm a DIY'er and I'm going to find a way to take this apart and disable the light. I'll report back if I'm successful. The good news is that this mount is identical to another one I have except for the magnet charging section. I'm talking it is identical down to the knobs and metal arm so it's generic in that sense. They only changed out the magnetic section. This type of mount holds well to the screen. The charging speed seemed adequate. Not terribly fast but not slow. Wirelessly charging is always slower than plugged in. The supplied USB cable is braided and feels like quality. See attached picture. This mount is not something you'll necessarily want to use every time you drive. Therefore the color ring is annoying.
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SLEEK EXTENDABLE SCREEN MOUNT
HIGH SPEED TESLA MAGSAFE POWER i picked this up for my Model 3 to see if the 25W Qi2.2 charging actually lives up to the hype during my daily work week. ✨ The CNC aluminum build is top notch and feels much more robust than the flimsy plastic mounts i have tested. It's a piece of cake to clamp onto the corner of the Tesla screen and the metal arm matches the interior aesthetics perfectly. The magnetic hold is strong enough to keep my phone secure even when i am taking sharp turns thru my weekend adventures. ✨ Performance is where this thing shines because it actually delivers the 25W speeds without overheating. The built in cooling fan is a smart design choice that keeps the temperature down during long drives. i can hear the fan if the music is off but it's barely noticeable and definitely worth it for the consistent charging speed. ✨ The RGB lighting adds a subtle glow that makes it easy to find the mount in the dark without being distracting. Having the extendable arm is a big benefit for finding the perfect line of sight without blocking the main touchscreen. It's clearly a well thought out solution for any Tesla owner who wants a professional grade charging setup. THE VERDICT This is a exceptional piece of hardware that delivers real world results for high speed charging. The combination of active cooling and a sturdy metal build makes it a first class addition to my car. 'As a 35 year veteran of the computer technology industry, I offer informed and experienced perspectives in my product reviews.' I will update this review if anything changes within 1 year. ★★★★★ (5 Stars): A 5 star rating indicates the product meets my expectations for its purpose.
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Reviewed in the United States on February 13, 2026
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Peter
Lowell, US
★★★★★ 5
Great Product!!!
Color: Black
**Overall impression** The Anker MagSafe Charger Compatible, MagGo 3-in-1 is a seamless blend of practicality and modern design. It’s compact enough for a nightstand or desk, yet versatile enough to handle multiple devices in one tidy setup. If you value cable-free convenience and a tidy charging solution, this is a standout choice. **What I liked** - **Strong MagSafe performance**: The magnetic alignment feels precise, snapping right into place on my iPhone 13/14/15 with reassuring stability. Wireless charging is quick and steady, even with a case on (I tested a standard silicone case and a slightly thicker one). - **3-in-1 convenience**: It’s not just a charger for your phone—the MagGo 3-in-1 includes a dedicated spot for AirPods or other wireless earbuds and a small stand for Apple Watch or another device, depending on your setup. This eliminates clutter and keeps essentials within arm’s reach. - **Sleek, minimal design**: The matte finish and low-profile footprint look great on a nightstand or desk. It blends in with most decor and doesn’t draw unwanted attention to the charging area. **Build quality**: Solid construction with quality materials. The stand holds devices steadily, and the cable management is thoughtful, helping to reduce cable chaos. **Ease of use**: Set up is straightforward—just plug in, place devices, and you’re charging. The integrated design means fewer cables and an cleaner surface. **Bottom line** If you’re after a convenient, stylish, all-in-one charging solution, the Anker MagSafe Charger Compatible, MagGo 3-in-1 delivers. It’s reliable, well-built, and surprisingly versatile, making it a strong upgrade over standard single-device chargers. The few caveats around ultra-thick cases and watch-fit are minor trade-offs for the convenience and organization it brings to your space.
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