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Description
Cycloastragenol - 10 mg, 30 capsulesCycloastragenol is a bioactive molecule derived from Astragalus, a botanical widely used in Traditional Chinese Medicine and prized for its adaptogenic, immune supporting, and whole body benefits. Emerging evidence suggests cycloastragenol may unlock key aspects of healthy aging; it is known to support: Telomerase activation* Healthy telomere length* Healthy DNA structure* Antioxidant activity* Optimized aging at the genetic level* View Certificate of
Cycloastragenol is a bioactive molecule derived from Astragalus, a botanical widely used in Traditional Chinese Medicine and prized for its adaptogenic, immune-supporting, and whole-body benefits. Emerging evidence suggests cycloastragenol may unlock key aspects of healthy aging; it is known to support:
- Telomerase activation*
- Healthy telomere length*
- Healthy DNA structure*
- Antioxidant activity*
- Optimized aging at the genetic level*
Research-Supported Benefits:
Supports telomere length and healthy aging. Telomere attrition is one of the hallmarks of aging. Telomeres are the protective caps of chromosomes and help protect them from degradation. Critically short telomeres have been associated with cellular senescence and other parts of the aging process. Cycloastragenol may help activate telomerase, the major enzyme responsible for maintaining telomere length.*Supports healthy cell cleanup and antioxidative status. Improvement in markers related to antioxidative status was observed in the presence of cycloastragenol in an animal study. Cycloastragenol was also shown to help support the elimination of senescent cells in another animal study.*
References:
Ikram M, Jo MH, Choe K, et al. Cells. 2021;10(10):2719.
Ip FCF, Ng YP, An HJ, et al. Neurosignals. 2014;22(1):52-63.
Zhang Y, Gao D, Yuan Y, et al. Int J Mol Sci. 2023;24(7):6554.
- May help activate telomerase, the major enzyme involved in adding back telomeric DNA to the ends of chromosomes, by regulating MAPK and Akt signaling pathways.*
- May help support cAMP response element binding (CREB) activation.* CREB helps regulate gene expression related to cell survival and replication in many cell types.
- May support antioxidant activity in the aging brain.*
| Supplement Facts | ||
|---|---|---|
| Serving Size: 1 Capsule |
||
| Servings Per Container: 30 |
||
| Amount Per Serving | %DV | |
| Cycloastragenol (from Astragalus membranaceus Extract) (root) |
10 mg | † |
| † Daily Value not established | ||
REV.06.24
- OTHER INGREDIENTS: Vegetable capsule, rice flour.
- DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, fish, shellfish, tree nuts, peanuts, sesame.
- SUGGESTED DAILY USE: Take one (1) capsule per day, or as directed by your healthcare professional.
-
NOTE: Store in a cool, dry place, away from direct sunlight. Do not use if tamper evident seal is broken or missing. KEEP OUT OF REACH OF CHILDREN.
-
CAUTION: Not intended for use if you are pregnant or nursing. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.
- Superior Absorption and Bioavailability. A pharmacokinetic study showed that cycloastragenol has superior absorption and bioavailability compared to astragaloside IV, the main active constituent in A. membranaceus. This is in part due to cycloastragenol's low molecular weight.
- Science-First Formulations: We source only the highest quality ingredients backed by validated research to help you achieve your longevity goals.
- Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.
- Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.
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Exchange/Return Notes
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4.1 ★★★★★
Based on 23 reviews
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Product Reviews
★★★★★ 4
Heavy Smallish Handle Wonderful Dutch Oven
Color: Red, Size: 5Qt
As many have noted this lidded Dutch Oven is extremely heavy. But it cooks and cleans up beautifully, is well made and attractive.
In my opinion the handles are relatively small for such a heavy pot, my one complaint. The mitts are cute but more decorative than truly protective as the handles are so small. Just be very careful picking up and moving the pot especially from the oven.
I chose the red color which looked vibrantly cheerful in my white kitchen. The 5 qt capacity works for modest to regular-sized portions without second helpings for 4-6 people. However, if cooking for more people, want larger portions, 2nd helpings or leftovers, go with a larger pot.
Overall, given its great construction, price, cooking performance, and attractiveness, this is a no-brainer purchase if you won’t mind relatively small handles and a heavy pot.
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Reviewed in the United States on January 24, 2026
★★★★★ 5
Perfect for sourdough
Size: 4.3 Qt, Color: Olive
Beautifully made. Great addition to my kitchen!
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Reviewed in the United States on June 6, 2026
★★★★★ 5
Heavy-Duty Dutch Oven That Easily Feeds a Big Family
Size: 6.0 Qt, Color: Clay, Size: 6.0 Qt, Color: Clay
I am extremely impressed with this Amazon Basics enameled cast iron Dutch oven. The first thing I noticed when I took it out of the box was how substantial and heavy it feels, which immediately gave me confidence in the quality. The clay color is beautiful and looks even better in person, and the enamel finish is smooth and well done. I have a large family, so I needed something with plenty of capacity, and this 6-quart size has been perfect for big batches of soup, chili, pot roast, and homemade pasta sauce. It heats evenly, retains heat exceptionally well, and keeps food warm for a long time after cooking. The lid fits securely and helps lock in moisture, which made a recent pot roast come out incredibly tender after several hours of slow cooking. The wide handles make it easy to move from the stovetop to the oven, and despite the weight, it feels very sturdy and well balanced. Packaging was excellent and everything arrived in great condition. Considering the quality, performance, and attractive design, this Dutch oven offers outstanding value for the price. If you're looking for a durable cast iron pot that can handle family-sized meals and perform like much more expensive brands, this one is an easy recommendation.
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Reviewed in the United States on June 2, 2026
★★★★★ 5
Quality Baking, Not Just For Meat Anymore
Size: 6.0 Qt, Color: Clay, Size: 6.0 Qt, Color: Clay
Since my wife is an avid sourdough baker, requesting this Dutch oven was an easy decision. From the moment I unboxed it, the first thing I noticed was the substantial weight—a testament to its high-quality cast iron core.
Beyond its heft, the Dutch oven features a beautifully smooth finish on the interior and exterior that makes it look as good as it performs. My wife has already put it to the test with two loaves of sourdough. While the first loaf browned a bit too much on the bottom, the second attempt turned out absolutely perfect, proving that it just takes a little practice to dial in the heat distribution.
I am confident we won’t limit this piece to just bread baking; I can already imagine a delicious chicken or pot roast in its future. If you are looking for a top-tier cooking utensil, you really can’t do much better than this. It is exceptionally well-made and expertly finished. Whether you are a dedicated baker or looking to cook up a perfectly tender roast, you will be doing yourself a favor by adding this Dutch oven to your kitchen collection.
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Reviewed in the United States on June 6, 2026
★★★★★ 5
You could pay a lot more, but why would you?
Size: 6.0 Qt, Color: Linen Gray
Technically, this is a French oven, which is enameled. A Dutch oven is bare cast iron.
I like these mainly for baking bread. The French oven traps the moisture coming out of the bread, and converts it to steam, which is essential for a good crust. (Search 'Jenny Can Cook no knead bread' for a recipe that is so simple and effective and forgiving that you will find it hard to believe it works, even after you've done it dozens of times.)
Long ago, I got a Le Creuset just like this, for about 10 times the price. I worked like crazy to keep it looking like new, but before too long, it looked like something from Goodwill.
As a test, I just made two loaves of bread, one in the Le Creuset, one in this, and I could not tell the difference. It may be that down the line, the Amazon Basics will crack, or sustain some damage to the enamel, or something like that. But I could replace it 9 times before spending as much as I spent on the Le Creuset!
As far as I can tell, you're getting the same quality, without paying for the name. Why wouldn't you do that?
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Reviewed in the United States on June 1, 2026
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