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Description
K9 Advantix II XL Dog Flea, Tick & Mosquito Treatment & PreventionK9 Advantix II Extra Large Dog is the veterinarian recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing
K9 Advantix II Extra Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Extra Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh over 55 lbs. to use K9 Advantix II Extra Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Extra Large Dog is a trademark of Elanco or its affiliates.
Key Features
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K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
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Kills fleas within 12 hours of application
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Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
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Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
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No prescription needed
Directions for Use
Use only on dogs. DO NOT USE ON CATS or other animals. Do not apply to dogs weighing less than 4 lbs. Remove applicator tube from the package. Use scissors and peel down foil. Hold applicator tube in an upright position. Pull cap off tube. Turn cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. The dog should be standing for easy application. Evenly apply entire contents of the tube along the top of the dog's back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label). At each spot, part the hair until skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.
Storage Instructions
Store in a cool, dry place inaccessible to children and pets. Protect from freezing.
Active Ingredients
Imidacloprid, Permethrin, Pyriproxyfen
Product Form
- Topical
Pet Size
- Extra Large
Pet Lifestage
- 7 weeks and older
Pet Weight
Over 55 lbs
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.7 ★★★★★
Based on 24 reviews
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Product Reviews
★★★★★ 2
It doesn’t do what is supposed to do
Color: Blue
Wasn’t impressed..,all the ball does is vibrate. It doesn’t really bounce
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Reviewed in the United States on March 6, 2026
★★★★★ 5
My dogs fight over it
Color: Orange, Color: Orange
Easy to use, durable, and has a great battery love. At first my dogs were curious and unsure about it, now its become one of their favorite toys. They'll stare at it while its being charged and impatiently wait for it so they can have fun again. Perfect size for most breeds.
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Reviewed in the United States on January 3, 2026
★★★★★ 5
Haru LOVES this toy!
I recently purchased the Amazon Basics Hide and Seek Squeaky Dog Plush Toy, Rabbit and Carrot 5 Pack, and it has been an absolute hit with my dog Haru! This set has quickly become his favorite playtime activity, and it's easy to see why.
From the moment I introduced Haru to the plush toys, he was hooked! The rabbit and carrot design is not only adorable but also adds an element of excitement and curiosity for him. The toys' quality is impressive, with sturdy stitching that has held up well to Haru's enthusiastic play style.
The "hide and seek" aspect of the toys is brilliant. Each plush toy contains squeakers, which immediately captured Haru's attention. He thoroughly enjoys searching for the source of the squeaky sound and then triumphantly "catching" the rabbit or carrot. It's like a mini-game that keeps him mentally stimulated and entertained.
One of the best things about this 5-pack set is the variety it offers. Haru never gets bored because he can alternate between the different plush toys, and each one presents a new challenge for him. Whether he's "hunting" the rabbit or "nibbling" on the carrot, his excitement is contagious!
Furthermore, I appreciate how these toys keep Haru engaged for a good amount of time. As a busy dog owner, it's essential to have toys that can entertain him while I'm occupied with other tasks. The Hide and Seek Squeaky Dog Plush Toy accomplishes this perfectly, giving me some peace of mind knowing Haru is happily occupied.
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Reviewed in the United States on July 21, 2023
★★★★★ 5
Great toy
Great size for a medium to large dog and a good value overall. The carrot foliage is made of felt and can tear easily, but the carrot body and bunnies have typical toy durability. The bunnies include squeakers that are softer and not high-pitched. The holes are sized well—small enough that the bunnies don’t fall out on their own. Even with only a few stuffed inside, they stay put until your dog pulls them out.
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Reviewed in the United States on November 30, 2025
★★★★★ 5
I was shocked by how much my daughter's puppy enjoyed this toy!
I've bought two of these — one for my grand puppy to use when she's at my house, and another for her to keep at her house. I was shocked that she actually seems to enjoy playing with this toy! She hunts out all the bunnies and then brings the carrot to me to refill. I refill it, and then she takes the refilled carrot back to her spot and hunts them all out again. If I can't find one of the bunnies (because it's gotten stuck in the couch cushion, for example), I ask her "where's the bunny?" and she helps me find it! This dog is a ferocious chewer but she doesn't chew these toys! It's like she instinctively knows they are for hunting, not chewing. As a result, they have lasted a long time and provide hours of quality fun. Great value!
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Reviewed in the United States on April 7, 2026