SKU: 690677477

NMN Pro™ Powder - Uthever® NMN, 500 grams

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Description

NMN Pro™ Powder - Uthever® NMN, 500 gramsHelps combat aging, improves heart health and promotes muscle strength NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression. Nicotinamide mononucleotide (NMN) is a derivative of the B vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+. NMN Pro Powder allows NMN to be

Helps combat aging, improves heart health and promotes muscle strength

  • NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression.
  • Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+.
  • NMN Pro Powder allows NMN to be absorbed directly into the blood vessels in the mouth and under the tongue, which increases the product's bioavailability. In this way, NMN avoids digestion in the gastrointestinal tract and can be more rapidly delivered into the bloodstream.

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Research-Supported Benefits:

Supports Longevity. Studies have shown that boosting NAD+ synthesis in the body extends the lifespan of yeast, worms and flies.1

Blood Sugar Regulation. As we age, we have more trouble processing glucose, leading to higher blood sugar. Supplemental NMN is shown to improve several markers of skeletal muscle glucose metabolism that are commonly dysregulated in people with metabolic disorders.2

Supports Metabolism and Healthy Weight. Although excessive body weight can develop at any age, adults over age 40 are particularly susceptible to age-related weight gain as metabolism slows down and body composition is altered to favor fat over lean muscle. As obese individuals have reductions in both NAD+ levels and ATP (energy) production, replenishing NAD+ through NMN can help to reverse this while improving metabolic pathways to maintain a healthy weight.3,4,5

Supports Healthy Cognition: Declining cognitive function with age is related to a reduced NAD+ levels that impair mitochondrial function. Replenishing NAD+ stores through NMN may be able to prevent this dysfunction.6,7

Supports Healthy Skin: In our 30s and 40s, the appearance of our skin can start to show signs of age. Several studies have examined how boosting NAD+ levels in the skin prevents premature skin aging or supports a healthier external appearance.8,9

References:

1. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016/j.cmet.2016.09.004 

2. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016/j.cmet.2016.09.004 

3. Feng Z, Qin Y, Huo F, et al. NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166287. doi:10.1016/j.bbadis.2021.166287 

4. Gopi S, Balakrishnan P. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. J Liposome Res. 2021;31(4):356-364. doi:10.1080/08982104.2020.1820521 

5. Katayoshi T, Nakajo T, Tsuji-Naito K. Restoring NAD+ by NAMPT is essential for the SIRT1/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes. J Photochem Photobiol B. 2021;221:112238. doi:10.1016/j.jphotobiol.2021.112238 

6. Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022;14(4):755. Published 2022 Feb 11. doi:10.3390/nu14040755 

7. Kiss T, Nyúl-Tóth Á, Balasubramanian P, et al. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020;42(2):527-546. doi:10.1007/s11357-020-00165-5 

8. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021;18(1):54. Published 2021 Jul 8. doi:10.1186/s12970-021-00442- 

9. Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016/j.cmet.2016.09.013 

10. Tarantini S, Valcarcel-Ares MN, Toth P, et al. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019;24:101192. doi:10.1016/j.redox.2019.101192 

11. Wang X, Hu X, Yang Y, Takata T, Sakurai T. Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death. Brain Res. 2016;1643:1-9. doi:10.1016/j.brainres.2016.04.060 

12. Yoshino J, Mills KF, Yoon MJ, Imai S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536. doi:10.1016/j.cmet.2011.08.014 

13. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126/science.abe9985

  • Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+, a compound that plays a crucial role in energy production, metabolism and gene expression in the body. When we boost NMN levels in the body, we can enhance the biosynthesis of NAD+ and alleviate symptoms associated with depletion of this crucial nutrient. NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, brain health, heart health, body weight and gene expression.
  • NMN Pro Powder allows NMN to be absorbed directly into the blood vessels in the mouth and under the tongue, which increases the product's bioavailability. In this way, NMN avoids digestion in the gastrointestinal tract and can be more rapidly delivered into the bloodstream.
Supplement Facts

Serving Size: 1 Level Scoop

Servings Per Container: 500
Amount Per Serving %DV
Uthever® β-Nicotinamide Mononucleotide (NMN)
1 g
† Daily Value not established.
REV.07.23
  • DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.
  • SUGGESTED DAILY USE: Place 1 level scoop under the tongue to dissolve then swallow, or mix in cold water or other beverage, or as recommended by your healthcare professional. 
  • CAUTION: Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.
  • NOTE: Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. Package filled by weight, not volume. KEEP OUT OF REACH OF CHILDREN.

Only Clinically-Proven NMN. ProHealth’s NMN is the only clinically-proven NMN to boost NAD+ levels in a peer-reviewed, double-blind, placebo-controlled, published, clinical study. Results of the study indicated a 38% increase in NAD+ levels and 12-year reversal in biological age.

Unique Delivery Method. NMN Pro Powder allows NMN to be absorbed directly into the blood vessels in the mouth and under the tongue, which increases the product's bioavailability.

Solvent-Free. Compared to other NMN products, ours is made without any chemical solvents.

Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.

Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.

Be Aware of Fake NMN: Fraudulent companies are always attempting to out-price competitors by using NMN fake ingredients to gain market share, which is not fair to you, the consumer, or the reputable companies, like ProHealth that spends time and resources to ensure a safe and pure NMN product.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 690677477

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lisa smith
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★★★★★ 3
PAWISE Pee Pad Holder * Big size *
Size: Small
You GUYS.....they shipped this damn thing in a 65inch TV box Do the measurements and then think about how big a that damn tv box is....literally it arrived and my husband & kids thought 1000% I bought a new TV. So far the product I am happy with / its a bigger square for those dancing pups. I am using this on a Chorkie puppy. The big pads fit and it latches them. Now the pup has realized he can pop the latches but he cant get the pad cause the lid is ontop . Im sure this is a puppy thing and will pass he got redirected and hasnt messed with it since. day 2 of use. *** THANKS JEFF & employees for the huge ass waste of cardboard LOL **
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Reviewed in the United States on October 9, 2021
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Susan
West Palm Beach, US
★★★★★ 5
Perfect for puppy!
Size: Small
I got this because I bought another (cheaper) alternative and the pads were shredded within the hour. This holder has the corners of the pad covered and that was the saving grace. Worth the extra money because you aren’t wasting money on puppy pads that are shredded before they are even used. If your puppy is still set on shredding, make sure to add lots of toys on a rotation (never the same toys everyday) and it helps a lot. Once I did that and changed the holder, no shredded puppy pads!
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Reviewed in the United States on October 30, 2021
M
Verified Purchase
Mm
Charlottesville, US
★★★★★ 1
Misleading size stated in adv.
Size: Small, Size: Small
Absolutely ridiculous! Says 23.5” by 23.5 “. It just barely measures a little more than 19 inches. You have to fold up the 24” by 24” per pad to fit it. I don’t know if my 5 pound chihuahua will be able to use it. A complete waste of money!! First photo shows it in frame - 2nd photo show what is a 24 by 24 pad.
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Reviewed in the United States on July 6, 2025
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Verified Purchase
Donna Martin
San Leandro, US
★★★★★ 5
FANTASTIC PAD HOLDER
Size: 28'' X 34'', Size: 28'' X 34''
Amazon Basics Dog Training Pad Holder 28X34. I'll start out by saying I wasn't too sure about it, when I got it. It is awkward to put the pads in by yourself if your short as on each end the sides have to come up together and it’s big, however, I've done it five times alone now and it’s doable. There was no smell, it arrived in perfect condition. My husband was home and we set it up together, I walked into the bathroom to get a soiled pad I had keep to put on it for her to know what to do came back and she had already used it and she’s only four months old. I love it love it love it, it’s not too big, but it’s her home too, and we have it in the living room where we spend a lot of time as we’re retired. When she gets a little older, we will probably move it to another room, but for now it’s staying there. After she urinates, it goes down to a very pale yellow color I have been able to use one pad for all day, however, she does have a pad in a under bed tote in our master bathroom. We’ve had a few guests over and if she hadn’t used it they didn’t even know what it was. I highly recommend it. I have been using pads in an under the bed tote for over 10 years and this is a welcome audition. You won’t be sorry if you have little ones that go in the house.
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Reviewed in the United States on January 1, 2026
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Mariana P.
San Leandro, US
★★★★★ 5
Very easy to use and clean
Size: 22'' X 22''
Saved my pad training with my puppy. It's firm and easy to clean. It holds the pads well for the most part, but sometimes my dog gets a little crazy and it comes out, but I don't think it could be better. Still give a 5-star!
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Reviewed in the United States on May 3, 2026

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