SKU: 57825988339

Sirtuin 6 Activator - 60 capsules

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Description

Sirtuin 6 Activator - 60 capsulesSirtuin 6 Activator: Inspired by the Blue Zones Activates sirtuin 6 (SIRT6)1,4,6,7* Provides Blue Zone bioactives*5,6 Supports multiple longevity pathways*5 Neutralizes free radicals*5,12 Supports a healthy immune system & inflammatory response* 8,5,9 11 View Certificate of Analysis Not all fucoidan is created equal. After three years of extensive research and testing, we've finally sourced an authentic Fucus vesiculosusa special type of seaweed

Sirtuin 6 Activator: Inspired by the Blue Zones

  • Activates sirtuin 6 (SIRT6)1,4,6,7*
  • Provides “Blue Zone” bioactives*5,6
  • Supports multiple longevity pathways*5
  • Neutralizes free radicals*5,12
  • Supports a healthy immune system & inflammatory response* 8,5,9-11

View Certificate of Analysis

Not all fucoidan is created equal. After three years of extensive research and testing, we've finally sourced an authentic Fucus vesiculosus—a special type of seaweed renowned for its powerful fucoidan content and abundant marine polyphenols. This premium seaweed extract sets a new benchmark in longevity science.* 2,5,8,13,21,22,25

What Makes Ours Better?

  • Fucoidan-Rich Seaweed: We deliver pure, concentrated seaweed—not synthetic compounds or low-quality extracts—packed with fucoidan, a potent SIRT6 activator.*21,22
  • Longevity Boost: Each serving provides a full 400mg dose of fucoidan, the scientifically-backed compound for healthy aging.*
  • Full Spectrum Support: Our formula blends whole-plant seaweed powder with high-potency extracts, offering a more complete range of bioactive compounds to amplify fucoidan’s anti-aging potential.*12,15
  • Maximized Bioactivity: Unlike many seaweed extracts that lose potency through harsh processing, our fucoidan is gently extracted using a specialized water-based method, preserving its full molecular structure for optimal effectiveness.*5

Why Choose ProHealth?

  • Doctor-Formulated: Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*
  • Triple Lab Tested: Subjected to three rounds of independent third-party lab testing to ensure unmatched potency and purity.
  • Full Transparency: In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle.
  • Manufactured in the USA: Made in FDA-regulated, GMP-certified facilities, adhering to the highest quality and safety standards.
  • 100-Day Risk-Free Guarantee: We’re confident you’ll love our product. If you’re not satisfied, contact our Santa Barbara, CA office for a full refund within 100 days—no hassle, no questions asked.

Not all fucoidan is created equal.

For centuries, Japan—home to one of the world’s longest-living populations—has relied on seaweed as a dietary staple, prized for its powerful antioxidants and cellular-protective compounds. Research consistently links regular seaweed consumption to enhanced health and longevity, reinforcing its vital role in healthy aging.*15

Building on this tradition, Sirtuin 6 Activator delivers fucoidan, one of seaweed’s most potent bioactive compounds. Naturally found in the cell walls of brown seaweed, fucoidan is clinically recognized for its ability to activate SIRT6, a key enzyme that supports healthy aging at the cellular level.*1


By activating SIRT6, this fucoidan-rich formula goes beyond simple antioxidant support to revitalize cellular health at its core. Research shows that increased SIRT6 activity can aid in DNA repair, boost genomic stability, and support a healthy systemic inflammatory response—processes linked to longevity in Blue Zone populations.*5,8,9,12,14,16

Emerging studies further suggest that higher SIRT6 activity correlates with longer lifespans in multiple animal species. Scientists are now exploring its potential for brain aging, heart health, and overall longevity, with human trials underway to further uncover its impact on healthy aging.*20,26-28


Sirtuin 6 Activator: Inspired by the Blue Zones

Aging is associated with cellular changes, including DNA damage, inflammation, and metabolic shifts, all of which have been studied in relation to SIRT6’s biological functions. Research suggests that SIRT6 plays a role in key cellular processes that support overall health.*

  • Supports DNA Repair – SIRT6 stabilizes the genome by repairing double-strand breaks and maintaining telomere integrity, reducing genetic instability, a major hallmark of aging.*6
  • Influences Metabolic Balance – SIRT6 shifts cells away from inefficient sugar metabolism and toward fat oxidation, mimicking the anti-aging effects of caloric restriction.*17
  • Clears Senescent Cells – Fucoidan acts as a potential senolytic, helping the body remove dysfunctional cells that drive aging.*4,13,19
  • Protects Mitochondria – SIRT6 supports healthy cellular energy production, safeguarding from oxidative stress so cells can generate energy efficiently.*5

Neutralizes Free Radicals*

Oxidative stress occurs when free radicals accumulate and damage cells, proteins, and DNA—a primary driver of aging. ProHealth Sirtuin 6 Activator combats oxidative damage through multiple pathways:

  • Directly Scavenges Free Radicals – Fucoidan’s unique sulfated polysaccharide structure binds to and neutralizes reactive oxygen species (ROS) before they can harm cells.*12
  • Provides Antioxidant Support – This formula combines fucoidan with polyphloroglucinols, marine polyphenols that strengthen cellular defenses against oxidative damage.*5
  • Enhances Cellular Antioxidant Pathways – By enhancing glutathione and superoxide dismutase (SOD) levels, SIRT6 supports the body’s natural ability to maintain oxidative homeostasis.*12

Supports a Healthy Immune System & Inflammatory Response*

Healthy immune system and inflammatory responses are essential for long-term health and longevity. Research suggests that fucoidan and SIRT6 may help support immune function and inflammation balance through multiple pathways:

  • Supports Immune Cell Activity – Fucoidan supports the activity of macrophages, natural killer (NK) cells, and lymphocytes, helping to maintain a robust immune system and clear damaged cells.*5,8,10
  • Helps Maintain a Healthy Inflammatory Response – SIRT6 influences cytokine activity and inflammatory response mechanisms, helping to support healthy inflammation for optimal aging.* 5,8,9
  • Enhances Gut-Immune Function – Fucoidan supports a healthy gut microbiome, which is closely linked to immune and inflammatory balance.*11

Order now and join the 200,000+ people who trust ProHealth Sirtuin 6 Activator for their cellular health!

Ingredients:

  • Brown Seaweed (Fucus vesiculosus): A rich source of fucoidan, a bioactive polysaccharide recognized for supporting cellular health and activating SIRT6, the longevity enzyme.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

References:

  1. Rahnasto-Rilla M et al. Mar Drugs. 2017;15(6):190.
  2. Kawaguchi T et al. Int J Oncol. 2015;46(5):2216-2222.
  3. Yu W et al. Mol Nutr Food Res. 2017;61(10):1700136.
  4. Cao L et al. Mar Drugs. 2020;18(11):564.
  5. Li B et al. Molecules. 2008;13(8):1671-1695.
  6. López-Otín C et al. Cell. 2023;186(2):243-278.
  7. Iso H and Kubota Y. Asian Pac J Cancer Prev. 2007;8 Suppl:35-80.
  8. Jayawardena TU et al. Mar Drugs. 2022;20(12):755.
  9. Apostolova E et al. Polymers. 2020;12(10):2338.
  10. Bogolitsyn K et al. Plant Foods Hum Nutr. 2024;79(2):511-517.
  11. Luthuli S et al. Mar Drugs. 2019;17(9):487.
  12. Catarino MD et al. Mar Drugs. 2018;16(8):249.
  13. Zhang L et al. Innov Aging. 2022;6(Suppl 1):130.
  14. Myers S et al. Biol Targets Ther. 2011;45.
  15. Myers S. Biol Targets Ther. 2010;33.
  16. Li X et al. Front Cell Dev Biol. 2021;9:641315.
  17. Zhang N et al. Cell Cycle. 2016;15(7):1009-1018.
  18. Chilton WL et al. PLoS ONE. 2014;9(4):e92088.
  19. Akter R et al. Int J Mol Sci. 2021;22(8):4180.
  20. Zhang L et al. Innov Aging. 2022;6(Suppl 1):130.
  21. Gorbunova V. Innov Aging. 2019;3(Suppl 1):S8.
  22. Kawamura A et al. Mar Drugs. 2021;19(8):452.
  23. Willcox DC et al. Ann NY Acad Sci. 2009;1173:126-138.
  24. Buettner D. Natl Geogr Books. 2015.
  25. Korotkov A et al. Trends Cell Biol. 2021;31(12):994-1006.
  26. Zhang L et al. Oxid Med Cell Longev. 2019;2019:8918914.
  27. Yang J et al. Int J Biol Macromol. 2024;277(Pt 3):134397.
  28. Wang K et al. Ther Adv Chronic Dis. 2022;13:20406223221076891.
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
Fucoidan (from Bladderwrack [Fucus vesiculosus] Whole Plant Extract and Brown Seaweed [Undaria pinnatifida] Whole Plant Extract) 400 mg
Bladderwrack (Fucus vesiculosus) Whole Plant Powder 100 mg
† Daily Value (DV) not established
REV.10.24

  • OTHER INGREDIENTS: Vegetable cellulose (capsule), microcrystalline cellulose, bamboo silica.
    • May contain traces of fish and/or shellfish residue.
  • SUGGESTED DAILY USE: Take one (1) capsule daily, or as directed by your healthcare professional.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.
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SKU: 57825988339

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B
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B. Stubby
Cuba, US
★★★★★ 3
A familiar story, just with…..less.
Format: Kindle
So, as other reviewers make clear, this is very similar to Pack Darling and The Beta. It’s much closer aligned with The Beta, in plot and maybe more like Pack Darling with characters. That being said, I don’t hate this…..but it wasn’t great either. It’s both books mentioned but just….less. Less angst, less emotion, less feeling. The plot feels very half fleshed out, and the “bad guy” feels underwhelming. I didn’t really feel any real emotions from and of the male leads, except maybe Oliver. The others fell sorta flat for me. And Mika makes herself out to be this big bad ass straight outta training and then we never see it from here again with the one fitting room incident as the exception. SPOILER: The whole, “Oh, I’m actually probably an Omega, but I don’t wanna be but I do actually wanna be but no one can ever know my secret that I do nothing to hide “ thing fell so flat. She never commutes to believing she was secretly an omega, but also mentions her “secret” a lot. It just felt so manufactured. I’m intrigued enough to read part 2 and see how the author closes everything out, but this is not one I’ll recommend or ever come back to.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 13, 2024
S
Verified Purchase
SR
Louisville, US
★★★★★ 5
Good start to a series
Format: Kindle
I delayed reading the series for reasons I don’t remember. But my TBR list is huge so I thought I’d take a shot of this and I was pleasantly surprised. I didn’t think the blurb about it was anything special. But it was a very good book. It took some interesting twists and turns. I am so glad the second book is already out. Because I would not have waited patiently. Very slow burn but good storyline. 🔥🔥/5
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 3, 2025
J
Verified Purchase
Jammie Clark
Massapequa, US
★★★★★ 4
A good read
Format: Kindle
Multiple points of view. 3 Alpha men and an Omega male. She is a Beta in training for a new program placing betas in Alpha/Omega packs. Mila is only doing the program for the money to take care of her dad. She wasn't expecting to fall for a pack but when she sees this packs Omega she is done for. There is just something about him. His Alphas are good looking as well. Too bad she is hiding a secret and their government is acting shady. I liked it and can't wait to see where their story goes.
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Reviewed in the United States on November 14, 2023
B
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Bri Hires
Whiting, US
★★★★★ 3
Slightly repetitive but I did love some things
Format: Kindle
I love this type of story. And omegaverse is one of my all time favorite genres. But there are a few things that pulled me out of my enjoyment while I was reading. It was repetitive at times as well as struggled with telling not showing. So we didn’t always feel like we were experiencing things with the main character. There were also some plot holes but they may still be answered in part 2. Now this isn’t to be said I didn’t enjoy parts of the story. I loved the almost instant love between Mila and Oliver. And how he started changing around her.
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Reviewed in the United States on February 15, 2024
K
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Kimberly G
Los Angeles, US
★★★★★ 5
delightful read
Format: Kindle
What a delightful read. The characters are awesome, the plot was so good, I loved it. I was intrigued and it kept me wanting more. Told in multiple pov, the book sucks you in and doesn’t let go. I cannot wait to read the next book.
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Reviewed in the United States on January 30, 2025

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