SKU: 49439581887

Pterostilbene Pro 250 - 250 mg, 60 capsules

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Description

Pterostilbene Pro 250 - 250 mg, 60 capsulesPterostilbene is a powerful antioxidant that is similar to, but more bioavailable than resveratrol. Pterostilbene promotes longevity and improves markers associated with heart and brain health. Supports cardiovascular health* Promotes brain cell health* Activates sirtuins to support healthy aging Boosts effectiveness of NMN View Certificate of Analysis Research Supported Benefits: Supports Longevity. Pterostilbene activates longevity genes known as

Pterostilbene is a powerful antioxidant that is similar to, but more bioavailable than resveratrol. Pterostilbene promotes longevity and improves markers associated with heart and brain health.

  • Supports cardiovascular health* 
  • Promotes brain cell health* 
  • Activates sirtuins to support healthy aging 
  • Boosts effectiveness of NMN 

View Certificate of Analysis

Research-Supported Benefits:

Supports Longevity. Pterostilbene activates “longevity genes” known as sirtuins. Research shows that activating sirtuins promotes cellular health and extends lifespan of animals. 1 2 Activating sirtuins aids in DNA repair, promoting cellular stress resistance, regulating autophagy (cellular detoxification) and inflammation. 3

Promotes Heart Health. Research shows that pterostilbene promotes heart health in a variety of ways, one of which is reducing oxidative stress of the heart. 4 Oxidative stress contributes to inflammation and accelerated aging of heart cells. Reducing levels of oxidative stress reduces risk of age-related decline of heart health.

Protects the Aging Brain. Pterostilbene has been shown to reduce neuroinflammation (inflammation of brain cells), reducing oxidative-stress-related damage to brain cells 5. Research shows that neuroinflammation contributes to age-related brain decline symptoms such related to memory and information processing.6

References:

1. Cheng Y, Di S, Fan C, et al. SIRT1 activation by pterostilbene attenuates the skeletal muscle oxidative stress injury and mitochondrial dysfunction induced by ischemia reperfusion injury. Apoptosis. 2016;21(8):905-916. doi:10.1007/s10495-016-1258-x 

2. Lee SH, Lee JH, Lee HY, Min KJ. Sirtuin signaling in cellular senescence and aging. BMB Rep. 2019;52(1):24-34. doi:10.5483/BMBRep.2019.52.1.290 doi:10.5483/BMBRep.2019.52.1.290 

3. Vazquez BN, Thackray JK, Serrano L. Sirtuins and DNA damage repair: SIRT7 comes to play. Nucleus. 2017;8(2):107-115. doi:10.1080/19491034.2016.1264552

4. Kosuru R, Kandula V, Rai U, Prakash S, Xia Z, Singh S. Pterostilbene Decreases Cardiac Oxidative Stress and Inflammation via Activation of AMPK/Nrf2/HO-1 Pathway in Fructose-Fed Diabetic Rats. Cardiovasc Drugs Ther. 2018;32(2):147-163. doi:10.1007/s10557-018-6780-3

5. Park B, Lee YJ. Pterostilbene Improves Stress-Related Behaviors and Partially Reverses Underlying Neuroinflammatory and Hormonal Changes in Stress-Challenged Mice. J Med Food. 2021;24(3):299-309. doi:10.1089/jmf.2020.4766

6. Ahmad MA, Kareem O, Khushtar M, et al. Neuroinflammation: A Potential Risk for Dementia. Int J Mol Sci. 2022;23(2):616. Published 2022 Jan 6. doi:10.3390/ijms23020616

  • Pterostilbene has been shown to activate longevity genes known as sirtuins, which play a critical role in regulating cellular aging. 
  • Sirtuins require NAD+ for fuel, making pterostilbene and NMN a perfect supplement combination to promote longevity. 
  • By activating sirtuins, pterostilbene supports DNA stability and promotes DNA repair. 
  • Pterostilbene’s antioxidant effects promote heart and brain health by reducing oxidative stress and inflammation. 
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
Pterostilbene 250 mg
† Daily Value (DV) not established.
REV.08.25 

  • OTHER INGREDIENTS: Hypromellose (capsule), rice flour.
  • SUGGESTED DAILY USE: Take one (1) capsule 1-2 times per day, preferably with food.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF  CHILDREN. Store in a cool and dry place aer opening.

Clinical-Supported Dosing. ProHealth Longevity’s Pterostilbene Pro 250 contains 250 mg of pterostilbene per serving, a clinically effective dose to promote longevity.

Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.

Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
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Exchange/Return Notes
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  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
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SKU: 49439581887

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NO-BULL---- john
San Leandro, US
★★★★★ 5
Terrific toy for heavy chewers
Size: 6 in, Color: Blue
My dog loves this! Chews and plays with it constantly. These will last a long time, however, eventually they begin to break down. THEN GET ANOTHER, lasted a couple months with constant chewing.
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Reviewed in the United States on August 29, 2025
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CJB
Phoenix, US
★★★★★ 3
My dog doesn't like it
Size: 5 in, Color: Orange
My dog wasn't a fan of this at all. He was curious about it, probably because he could smell it, but he wasn't sure about chewing it. It could be because his teeth squeak against it? Or maybe it has an odd texture? I don't know But this has sat in the toy bin untouched since the day we got it
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Reviewed in the United States on October 13, 2025
E
Verified Purchase
Exactly as described on Amazon works perfectly great quality in product and pictures.
Waukegan, US
★★★★★ 4
Not for older dogs
Size: 6 in, Color: Blue
Item was on point as described, but my elderly dog was not interested.
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Reviewed in the United States on March 2, 2026
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De Marby Reviews
Battle Creek, US
★★★★★ 5
Great Chew Toy for Daily Play
Size: 6 in, Color: Blue, Size: 6 in, Color: Blue
My dog absolutely loves this toy. From the first moment he grabbed it, he wouldn’t stop playing with it. He chews on it, runs around with it, and even sleeps with it sometimes. What I like most is how durable it is — even with constant biting, pulling, and chewing, it hasn’t broken or shown any damage. The material feels strong but still safe for him to chew. The texture also seems to keep him entertained because it massages his gums while he plays. It’s lightweight, easy for him to carry, and the shape makes it fun for both chewing and tossing. This toy has become one of his favorites, and I’m really happy with the quality. I would definitely recommend it for dogs who love to chew.
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Reviewed in the United States on November 19, 2025
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Valerie Stapleton
Whiting, US
★★★★★ 5
Longest lasting toy in our toy box
Size: 6 in, Color: Blue
My German shepherd/Austrian shepherd mix destroys toys very quickly. This is his longest lasting toy that he actually uses and still has no visible signs of destruction.
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Reviewed in the United States on June 11, 2026

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