SKU: 26887216666

Pterostilbene Pro 250 - 250 mg, 60 capsules

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Description

Pterostilbene Pro 250 - 250 mg, 60 capsulesPterostilbene is a powerful antioxidant that is similar to, but more bioavailable than resveratrol. Pterostilbene promotes longevity and improves markers associated with heart and brain health. Supports cardiovascular health* Promotes brain cell health* Activates sirtuins to support healthy aging Boosts effectiveness of NMN View Certificate of Analysis Research Supported Benefits: Supports Longevity. Pterostilbene activates longevity genes known as

Pterostilbene is a powerful antioxidant that is similar to, but more bioavailable than resveratrol. Pterostilbene promotes longevity and improves markers associated with heart and brain health.

  • Supports cardiovascular health* 
  • Promotes brain cell health* 
  • Activates sirtuins to support healthy aging 
  • Boosts effectiveness of NMN 

View Certificate of Analysis

Research-Supported Benefits:

Supports Longevity. Pterostilbene activates “longevity genes” known as sirtuins. Research shows that activating sirtuins promotes cellular health and extends lifespan of animals. 1 2 Activating sirtuins aids in DNA repair, promoting cellular stress resistance, regulating autophagy (cellular detoxification) and inflammation. 3

Promotes Heart Health. Research shows that pterostilbene promotes heart health in a variety of ways, one of which is reducing oxidative stress of the heart. 4 Oxidative stress contributes to inflammation and accelerated aging of heart cells. Reducing levels of oxidative stress reduces risk of age-related decline of heart health.

Protects the Aging Brain. Pterostilbene has been shown to reduce neuroinflammation (inflammation of brain cells), reducing oxidative-stress-related damage to brain cells 5. Research shows that neuroinflammation contributes to age-related brain decline symptoms such related to memory and information processing.6

References:

1. Cheng Y, Di S, Fan C, et al. SIRT1 activation by pterostilbene attenuates the skeletal muscle oxidative stress injury and mitochondrial dysfunction induced by ischemia reperfusion injury. Apoptosis. 2016;21(8):905-916. doi:10.1007/s10495-016-1258-x 

2. Lee SH, Lee JH, Lee HY, Min KJ. Sirtuin signaling in cellular senescence and aging. BMB Rep. 2019;52(1):24-34. doi:10.5483/BMBRep.2019.52.1.290 doi:10.5483/BMBRep.2019.52.1.290 

3. Vazquez BN, Thackray JK, Serrano L. Sirtuins and DNA damage repair: SIRT7 comes to play. Nucleus. 2017;8(2):107-115. doi:10.1080/19491034.2016.1264552

4. Kosuru R, Kandula V, Rai U, Prakash S, Xia Z, Singh S. Pterostilbene Decreases Cardiac Oxidative Stress and Inflammation via Activation of AMPK/Nrf2/HO-1 Pathway in Fructose-Fed Diabetic Rats. Cardiovasc Drugs Ther. 2018;32(2):147-163. doi:10.1007/s10557-018-6780-3

5. Park B, Lee YJ. Pterostilbene Improves Stress-Related Behaviors and Partially Reverses Underlying Neuroinflammatory and Hormonal Changes in Stress-Challenged Mice. J Med Food. 2021;24(3):299-309. doi:10.1089/jmf.2020.4766

6. Ahmad MA, Kareem O, Khushtar M, et al. Neuroinflammation: A Potential Risk for Dementia. Int J Mol Sci. 2022;23(2):616. Published 2022 Jan 6. doi:10.3390/ijms23020616

  • Pterostilbene has been shown to activate longevity genes known as sirtuins, which play a critical role in regulating cellular aging. 
  • Sirtuins require NAD+ for fuel, making pterostilbene and NMN a perfect supplement combination to promote longevity. 
  • By activating sirtuins, pterostilbene supports DNA stability and promotes DNA repair. 
  • Pterostilbene’s antioxidant effects promote heart and brain health by reducing oxidative stress and inflammation. 
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
Pterostilbene 250 mg
† Daily Value (DV) not established.
REV.08.25 

  • OTHER INGREDIENTS: Hypromellose (capsule), rice flour.
  • SUGGESTED DAILY USE: Take one (1) capsule 1-2 times per day, preferably with food.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF  CHILDREN. Store in a cool and dry place aer opening.

Clinical-Supported Dosing. ProHealth Longevity’s Pterostilbene Pro 250 contains 250 mg of pterostilbene per serving, a clinically effective dose to promote longevity.

Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.

Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
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Exchange/Return Notes
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  • To process your return/exchange, please contact us at [email protected]
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SKU: 26887216666

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TB
Grantham, US
★★★★★ 4
My dog’s favorite soft toy!
Style: Plush Surprise Color, Size: 12", Style: Plush Surprise Color, Size: 12"
My dog loves these toys! We will get a replacement for him every couple months or so because these are his favorite. The squeaker is his arch nemesis and it’s always his main priority to get that first. The material is very soft so he likes to lightly chew on it when he gets anxious or excited, only negative is that it does tear easy but there’s not a lot of stuffing so it’s not a big mess to clean. Definitely recommend to puppies and dogs that don’t annihilated their toys.
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Reviewed in the United States on April 26, 2026
D
Verified Purchase
D.G.
Carnegie, US
★★★★★ 5
Puppy and price approved!
Style: Latex Surpise Color, Size: 6"
Great cheap little dog toys! Our 11 month large breed 90lb puppy loves to toss these around and squeak them between his teeth.. they eventually break down but that’s okay, at the low price of a couple to a few dollars each they make it affordable. They put some stuffing inside so it makes it slippery when our pup is nibbling on it. Funny enough these last longer than much more expensive toys that claim more durability! In 8 months we’ve gone through 2. That’s pretty good! Not chew resistant, but the latex offers a texture and squeak that I find makes our puppy go easier on them. Cute and easily packable.
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Reviewed in the United States on April 2, 2026
J
Verified Purchase
J. G.
New York, US
★★★★★ 3
Lab tested. Lab approved.
Style: Plush Surprise Color, Size: 24"
My two Labradors make quick work of these. They love them. But Not very durable. Stuffing everywhere.
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Reviewed in the United States on May 21, 2026
M
Verified Purchase
M. G. Dolan
Massapequa, US
★★★★★ 5
Our dog loves them
Style: Latex Surpise Color, Size: 6"
Not for every type of dog, but our dog LOVES these things. Try one and see how it goes. They are cheap, so no great loss if your dog doesn't like it, But if it does, you'll have a great time with them. Best $3 I could spend
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Reviewed in the United States on May 20, 2026
D
Verified Purchase
David M.
Chelsea, US
★★★★★ 4
Tie a Knot in it if it rips
Style: Plush Surprise Color, Size: 6", Style: Plush Surprise Color, Size: 6"
My puppy split the middle belly seam in about 5 minutes of spirited play with the white foam and squeak assembly scattered about, but he loves these loofa toys - goes nuts for them. Went through a couple of the little $3 ones so I tried this big one which he ripped apart. But I tied a knot in the middle of it over the ripped part and guess what, it's better than before. He loves the whipping the big knot around. The part where it ripped was where they filled it I think but the rest of the stitching is really quite solid. Takes a beating, to a point. The little ones lasted a reasonable time before they were totally played.
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Reviewed in the United States on February 15, 2026

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