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Description
PharmaGABA 250 - 60 capsGamma aminobutyric acid (GABA) is a major calming brain chemical or neurotransmitter.* Clinical studies show that the natural form of GABA that is in Thorne's PharmaGABA can decrease the brain's stress related beta waves and increase the production of its alpha waves, creating a profound sense of physical relaxation while maintaining mental focus.* Other studies have shown reduced pupil diameter, heart rate, and two natural biomarkers of stress
Gamma-aminobutyric acid (GABA) is a major calming brain chemical or neurotransmitter.* Clinical studies show that the natural form of GABA that is in Thorne's PharmaGABA can decrease the brain's stress-related beta waves and increase the production of its alpha-waves, creating a profound sense of physical relaxation while maintaining mental focus.* Other studies have shown reduced pupil diameter, heart rate, and two natural biomarkers of stress – salivary cortisol and chromogranin A – all signs of relaxation.* In addition, studies also indicate GABA can enhance sleep.* In a head-to-head, double-blind trial of natural PharmaGABA versus synthetic GABA, the synthetic GABA did not demonstrate these positive effects.* PharmaGABA-250 offers 250 mg of natural GABA per capsule, while PharmaGABA-100 offers 100 mg per capsule. Both are non-habit forming.
In a recent study of the effect of nutrient supplementation on muscle mass, 21 males, average age 39, who did not exercise regularly, were given 10 grams of whey protein or 10 grams of whey protein plus 100 mg of PharmaGABA daily for 12 weeks. Both groups participated in twice weekly 60-minute strength training sessions that consisted of leg presses, leg extensions, leg curls, chest presses, and pull-downs. Total body lean muscle mass increased significantly in the whey protein-plus-PharmaGABA group compared to the whey-only group.*
The natural GABA in Thorne's PharmaGABA suite is produced via a fermentation process that utilizes Lactobacillus hilgardii, the same bacteria that is used to ferment cabbage in the preparation of the traditional Korean dish known as kimchi.
In a recent study of the effect of nutrient supplementation on muscle mass, 21 males, average age 39, who did not exercise regularly, were given 10 grams of whey protein or 10 grams of whey protein plus 100 mg of PharmaGABA daily for 12 weeks. Both groups participated in twice weekly 60-minute strength training sessions that consisted of leg presses, leg extensions, leg curls, chest presses, and pull-downs. Total body lean muscle mass increased significantly in the whey protein-plus-PharmaGABA group compared to the whey-only group.*
The natural GABA in Thorne's PharmaGABA suite is produced via a fermentation process that utilizes Lactobacillus hilgardii, the same bacteria that is used to ferment cabbage in the preparation of the traditional Korean dish known as kimchi.
Take 1 capsule one to three times daily or as recommended by your health professional.
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4.7 ★★★★★
Based on 15 reviews
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Product Reviews
★★★★★ 5
Our Dog Loves This One
We got our dog two nylabones and this benebone and he really prefers this one. Like the nylabones he barely even looked at, but he loves this one so much it's starting to splinter off a little. Apparently it can just be sanded down again but I'll probably end up getting more of these so that we can switch them out. I noticed that the shape also helps him be able to handle it with his paws.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 24, 2026
★★★★★ 5
Initially showed little interest, then decided she loved it
The product itself looks great and is clearly very well made but my dog had zero interest initially in this which I find odd because many other similar toys she has attacked.
Update —- several weeks later all of a sudden my dog decided she liked this and started chewing on it and has been her favorite - go figure
Update 2 — it’s become her favorite chew and she’s obsessed with it! My older dog started chewing on it, and it broke one of her old teeth!
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Reviewed in the United States on February 27, 2026
★★★★★ 3
Chew toy
We have 8 pound 5 month pup she can chew up and end in about a week nylon should be a bit harder.
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Reviewed in the United States on May 24, 2026
★★★★★ 5
Wishbone
My dog, George loves it. Chews it a lot.
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Reviewed in the United States on April 21, 2026
★★★★★ 1
To not break a tooth.
Too hard.
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Reviewed in the United States on May 18, 2026
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