SKU: 97407226346

Human LIF, His tag

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Description

Human LIF, His tagProduct Specification Species Human Synonyms Differentiation stimulating factor (D factor), Melanoma derived LPL inhibitor (MLPLI), HILDA Accession P15018 Amino Acid Sequence Protein sequence (P15018, Met1 Phe202, with C 10*His) MKVLAAGVVPLLLVLHWKHGAGSPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKKLGCQLLGKYKQIIAVLAQAFGGGGSHHHHHHHHHH

Product Specification


Species Human
Synonyms Differentiation-stimulating factor (D factor), Melanoma-derived LPL inhibitor (MLPLI), HILDA
Accession P15018
Amino Acid Sequence

Protein sequence (P15018, Met1-Phe202, with C-10*His) MKVLAAGVVPLLLVLHWKHGAGSPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKKLGCQLLGKYKQIIAVLAQAFGGGGSHHHHHHHHHH

Expression System HEK293
Molecular Weight Predicted MW: 23.7 kDa Observed MW: 33-43 kDa
Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Tag with C-10*His
Physical Appearance Lyophilized Powder
Storage Buffer Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

Background

Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. LIF derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. It has been suggested that recombinant human LIF might help to improve the implantation rate in women with unexplained infertility. LIF is often added to stem cell culture media as an alternative to feeder cell culture, due to the limitation that feeder cells present by only producing LIF on their cell surfaces. LIF promotes self-renewal by recruiting signal transducer and activator of transcription 3 (Stat3).

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Exchange/Return Notes
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SKU: 97407226346

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4.2 ★★★★★
Based on 11 reviews
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A
Verified Purchase
Alp acct
Belleville, US
★★★★★ 4
doesn't whistle as loud as other chuckit balls I've seen, but a good ball.
makes some noise, but I've seen (and played with) others at the dog park that whistle much louder than the 1 I got. all Chuckit balls... so, just this one I'm betting. but it flys good and the dog loves to chase it. he chews it a fair bit as well and the ball has not taken much damage from him (lab mix) or others that have had a go at it. I'll likely buy another at some point ... just wish it was a little louder when flying.
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Reviewed in the United States on November 4, 2025
K
Verified Purchase
KA
San Leandro, US
★★★★★ 5
Blue ball, my dog likes blue.
Just a ball right? Evidently not! My dog won’t chase an orange chuck it ball or the glow in the dark ball- only the blue one 🤷🏼‍♀️
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Reviewed in the United States on May 9, 2025
B
Verified Purchase
Baker-s
Bozeman, US
★★★★★ 3
I wanted a blue ball
It's great. It just wasn't blue.
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Reviewed in the United States on January 5, 2026
J
Verified Purchase
Jr
Fort Morgan, US
★★★★★ 5
its a great ball
works well
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Reviewed in the United States on July 8, 2025
A
Verified Purchase
Amazon Customer
Bozeman, US
★★★★★ 5
Just right for a small dog
Pattern Name: Half Ears, Size: 25 Count (Pack of 1)
Perfect for my 9 lb mini schnauzer. It's her #1 favorite treat. Keeps her busy for a long time (a few hours). Great quality. Bag lasts a long time. Have purchased multiple times.
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Reviewed in the United States on May 28, 2026

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