Pay in installments of $40.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 30 - Aug 4
For Your Every Summer RSVP, with Code: SUMMER15
Description
Alexa Fluor® 700 Mouse Anti-Human CD123 Antibody (S-R442)Product Specification Host Mouse Antigen CD123 Synonyms Interleukin 3 receptor subunit alpha; IL 3 receptor subunit alpha; IL 3R subunit alpha; IL 3R alpha; IL 3RA; IL3R; IL3RA Location Cell membrane Accession P26951 Clone Number S R442 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein A Concentration 0. 2 mg ml Conjugation Alexa Fluor 700 Physical Appearance Liquid Storage Buffer
Product Specification
| Host | Mouse |
| Antigen | CD123 |
| Synonyms | Interleukin-3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; IL3R; IL3RA |
| Location | Cell membrane |
| Accession | P26951 |
| Clone Number | S-R442 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human PBMC |
| Purification | Protein A |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 700 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Hu |
Background
CD123, also known as interleukin-3 receptor alpha chain (IL-3Rα), is a 75 kDa type-I transmembrane glycoprotein that pairs with the common β-subunit (CD131) to form the high-affinity IL-3 receptor, triggering JAK/STAT, PI3K/AKT and MAPK cascades that drive proliferation, survival and differentiation of hematopoietic stem/progenitor cells, plasmacytoid dendritic cells, basophils and eosinophils; it is constitutively over-expressed on blasts and leukemic stem cells in >90 % of acute myeloid leukemias, B-ALL and blastic plasmacytoid dendritic cell neoplasm, making it a key diagnostic biomarker and a validated target for monoclonal antibodies, antibody-drug conjugates, bispecific T-cell engagers and CAR-T/CAR-NK therapies.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy