SKU: 94810547225

Invivo Anti-Mouse CD11c Recombinant mAb

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Description

Invivo Anti-Mouse CD11c Recombinant mAbProduct Specification Host Armenian hamster Antigen CD11c Synonyms Integrin alpha X; CD11 antigen like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; Itgax Location Membrane Accession Q9QXH4 Clone Number S R518 Antibody Type Recombinant mAb Application Functional assays Reactivity Ms Purification Protein G Concentration 5 mg ml Purity >95% (Determined by SDS PAGE) Endotoxin <1EU mg

Product Specification


Host Armenian hamster
Antigen CD11c
Synonyms Integrin alpha-X; CD11 antigen-like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; Itgax
Location Membrane
Accession Q9QXH4
Clone Number S-R518
Antibody Type Recombinant mAb
Application Functional assays
Reactivity Ms
Purification Protein G
Concentration 5 mg/ml
Purity >95% (Determined by SDS-PAGE)
Endotoxin <1EU/mg
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, containing no preservative
Stability & Storage

2 to 8 °C for 2 weeks under sterile conditions;
-20 °C for 3 months under sterile conditions;
-80 °C for 24 months under sterile conditions.
Please avoid repeated freeze-thaw cycles.

Background

CD11c, also known as integrin alpha X (ITGAX), is a ~150 kDa type I transmembrane glycoprotein that pairs non-covalently with the 95 kDa beta2 integrin CD18 to form the αXβ2 heterodimer (complement receptor 4, CR4), which mediates cell adhesion, migration, and phagocytosis by binding diverse ligands such as iC3b, fibrinogen, ICAMs, and denatured proteins; it is predominantly expressed on myeloid dendritic cells, tissue macrophages, activated monocytes, and some B-cell subsets, serving as a classic marker for conventional dendritic cells in both mice and humans, and plays crucial roles in immune surveillance, antigen presentation, and inflammatory responses while also being implicated in autoimmune diseases and serving as a therapeutic target in cancer immunotherapy.

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Exchange/Return Notes
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SKU: 94810547225

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4.3 ★★★★★
Based on 5 reviews
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O
Verified Purchase
Oma Q
New York, US
★★★★★ 4
Great entertaining toy
Color: Yellow
This is such a great you to help get some energy out of my little pup. She spends long amounts of time chasing and carrying it around. Entertains her for quite a while. The only draw back is the string that she carries it around with wears thin and break. If there were replacement ones I would buy them.
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Reviewed in the United States on April 7, 2026
A
Verified Purchase
Amanda
Houston, US
★★★★★ 5
Great interactive toy for pets
Color: Red
Very amusing interactive toy for pets! Our toddler got a kick out of this too :) Keeps our dog entertained and engaged. The battery life was decent and easy to recharge. It has 3 different settings for the movement depending what your pet likes. We had it go under furniture in hard to reach spots, but it is pretty good at moving itself out which is a plus. Great toy if your pet likes to chase.
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Reviewed in the United States on May 5, 2026
A
Verified Purchase
A. F.
Omaha, US
★★★★★ 5
One of the Best Toy I’ve Gotten My Dog-Now Buying Our 5th Because He’s Obsessed
Color: Blue
My small mixed breed dog is high intelligence, energy and emotion. Since he was a 2lb puppy, he’s gotten bored with regular dog toys. I came across these when searching for a ball that lights up, not knowing it would be one of the best things I could’ve purchased for him. He plays with it so often that I ended up buying 2 more shortly after the first one. I did that so I could have them charging while he plays with one. They stay charged for a few days if they’re not used much, but he plays with them all throughout the day. They automatically take a nap after 5 minutes of no activity and wake up if moved within 30 minutes. After 30 minutes, you have to turn them back on. He plays with it so often that I only have to turn it on once or twice a day. They’re easy to turn on. You just hold the power button for a couple of seconds and then press it to cycle through to the color of the corresponding setting you want. There are three different settings that combine movement and vibration. I love that no matter what setting you choose, the movement is always randomized, which keeps him from getting bored with it. We’ve had them about 5 months and they all still work, which is amazing because he’s so hard on them. He grabs them by the string and swings them around, hits them against the hard floor, and basically bumps everything nearby with them. They’re made of extremely hard plastic and the ball is covered in rubber. So it helps keep it quieter when zooming through the house. It’s impressive how tough these things are. The first one I bought just got a crack in it two days ago after he smacked it repeatedly on concrete, so they’re surprisingly well made. They sound like a Hot Wheels or tiny race car. The only noise they make really besides the zoom sound when they’re rolling is the vibrating or if they bump into something. Which if they run into a wall, they change direction like a Roomba does. I’m now buying two more because the strings are just now beginning to fray after about 5 months and because he now wants to have two going at the same time. I’ve also bought him an animatronic lobster and a quail for the same reason as these. They all keep him busy and engaged. If he’s awake, he’s making up games using all three of the toys. The animatronics are the same thing where you charge them up, the nap and wake up when moved, and are randomized. I also have two of the lobsters and quail to charge while he plays with the other. The only automatic toy he has that makes noise is the animatronic quail which is programmed to make real quail sounds but quiet enough to not be distracting. These balls are the incredible and I give them to friends with dogs who all love them as well. If you’ve got a dog a dog that needs it’s mind engaged, I HIGHLY recommend these balls!!! I also recommend looking into cat toys because they’re much more entertaining and engaging than a squeaky toy.
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Reviewed in the United States on April 19, 2026
A
Verified Purchase
Amazon Customer
Pawtucket, US
★★★★★ 5
Pet Ball Toy is great!
Color: Red
Absolutely one of the best and most fun toys that our pup has gotten. She is entertained for hours! The interaction helps to keep her active us entertained! It is used by simply pushing the activation button. The material is durable and has survived even when she has chewed it. It is like an energizing bunny! We love it and so does our puppy
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Reviewed in the United States on May 2, 2026
C
Verified Purchase
C.Grif
Belleville, US
★★★★★ 3
Fun while it lasted
Color: Red
I have a 2-year-old Yorkie who absolutely loves chasing balls, so I was excited to try this toy thinking it would keep him entertained for hours. Unfortunately, it didn’t hold up well. As soon as he caught it, he quickly bit the plastic piece off within just a few minutes. I understand that dogs can be tough on toys, especially with their natural hunting instincts, but I expected this to be a bit more durable. It just doesn’t seem sturdy enough for even a small dog who likes to chew and chase. In my opinion, this toy may be better suited for cats or very gentle play rather than active dogs.
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Reviewed in the United States on March 28, 2026

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