SKU: 89081781146

VDAC1 + VDAC2 + VDAC3 Rabbit Polyclonal Antibody

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Description

VDAC1 + VDAC2 + VDAC3 Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen VDAC1 + VDAC2 + VDAC3 Synonyms Voltage dependent anion selective channel protein; hVDAC1; Non selective voltage gated ion channel VDAC2; VDAC 2; Non selective voltage gated ion channel VDAC3; VDAC 3; hVDAC3; Outer mitochondrial membrane protein porin 3 Immunogen Synthetic Peptide Location Mitochondrion, Cell membrane, Endoplasmic reticulum Accession P21796Q9MZ15Q9Y277 Antibody Type Polyclonal antibody Isotype

Product Specification


Host Rabbit
Antigen VDAC1 + VDAC2 + VDAC3
Synonyms Voltage-dependent anion-selective channel protein; hVDAC1; Non-selective voltage-gated ion channel VDAC2; VDAC-2; Non-selective voltage-gated ion channel VDAC3; VDAC-3; hVDAC3; Outer mitochondrial membrane protein porin 3
Immunogen Synthetic Peptide
Location Mitochondrion, Cell membrane, Endoplasmic reticulum
Accession P21796、Q9MZ15、Q9Y277
Antibody Type Polyclonal antibody
Isotype IgG
Application WB, IHC-P
Reactivity Hu, Ms, Rt, Mk
Positive Sample HeLa, A431, Jurkat, HEK-293, HepG2, NIH/3T3, mouse heart, PC-12, rat heart
Purification Immunogen Affinity
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu, Ms, Rt
IHC-P 1:2000 Hu, Ms, Rt

Background

VDAC1, VDAC2, and VDAC3 are three closely related ~30 kDa β-barrel porins embedded in the mitochondrial outer membrane where they form voltage-dependent anion channels that collectively serve as the primary gatekeepers for metabolite flux—allowing ATP/ADP, NADH, ion, and other small-molecule exchange between cytosol and mitochondria—while also acting as hubs for Ca²⁺ signaling, apoptotic protein binding, and interaction with hexokinase, creatine kinase, Bcl-2 family proteins, and cytoskeletal elements; despite high sequence similarity, isoforms show tissue-specific expression (VDAC1 ubiquitous, VDAC2 enriched in heart/testis and uniquely anti-apoptotic via Bax inhibition, VDAC3 prominent in testis and cilia with redox-sensitive cysteines linked to sperm motility and ROS regulation), distinct electrophysiological gating properties, and differential roles in oxidative stress, mitochondrial dynamics, and apoptosis, making the trio essential for bioenergetics, cell survival decisions, and increasingly recognized as therapeutic targets in cancer, neurodegeneration, and metabolic disorders.

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SKU: 89081781146

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4.4 ★★★★★
Based on 15 reviews
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Product Reviews
J
Jamie K.
Belleville, US
★★★★★ 5
Perfect for Adding Privacy to a Piano Studio
Size: 2 Panel 8FT W, Size: 2 Panel 8FT W
I Ordered the 2 Panel version which is way too big for my needs... that's on me. So keep in mind that the picture shows a fabric made for two panels only being used on one and hence it is not pulled tight; it would pull tight and not be so wrinkly if it was set up properly as two panels. The metal pools that make up the panels seem to be well made, stable, and of good quality. They were very easy to put together and they stand up tall with plenty of height. The appearance of it with the fabric on it isn't as elegant as it could be, but it still looks good enough. The material is plenty solid, not allowing light through it, and thereby making a solid barrier. I am using it to block the view out the studio door when a student is sitting at the piano to avoid distractions from the hallway. It will allow a student to enter the studio with our distracting the student who is at the piano.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 18, 2026
J
Just Me
Bozeman, US
★★★★★ 5
Room Divider That Gives Instant “This Is a Separate Space Now” Energy
Size: 3 Panel 12FT W
The Siebwin 3 Panel Folding Privacy Screen is surprisingly effective at changing the feel of a room without requiring construction, commitment, or somebody yelling about load bearing walls. The 12 foot width gives a substantial amount of coverage, making it useful for creating privacy, dividing open areas, blocking visual clutter, or setting up temporary sections within larger rooms. This saved us a ton of time and money in our new studio and enabled us to create a kitchen and office in one room. The wider feet make a huge difference because flimsy room dividers that collapse every time someone exhales too aggressively are deeply annoying. This one feels more stable and grounded once positioned. The folding design makes it easy to move around or adjust depending on the space, and it folds down relatively compactly when not in use. It is basically the introvert curtain wall of dreams. The material has a clean, neutral look that blends well into different room styles without screaming “temporary office cubicle panic.” It works well for apartments, studios, shared spaces, dressing areas, or simply hiding the mountain of chaos you swear you are going to organize tomorrow. Practical, portable, and refreshingly easy to use without turning setup into a three hour emotional event.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 16, 2026
S
Skeetre
Fort Morgan, US
★★★★★ 4
It's 2 panels holding 1 big privacy screen. Can't use as 2 separate 4' panels, but works great.
Size: 2 Panel 8FT W
This 2 panel privacy screen works well. Assembly was very straight forward, with easily labeled tubes. My son and I had it together in about 10 minutes, which was probably 3 minutes of me telling him to quit playing around and hand me the parts. It feels very sturdy, not likely to fall over or anything. The material fits well, with the Velcro being very strong. Measurements are all very accurate, with all pieces attaching properly. We have a similar privacy screen at work that we have to try and stretch out because the top and bottom Velcro doesn't fit quite right... this model does not have any issues though. The material is thin and light weight, but solid black so that you can't see anything through or behind it. I definitely think it's a great deal for the money. What I think would have given it 5 stars though, is if you had 2 totally separate 4' panels instead of 2 panels with one big screen. It really wouldn't cost any extra to make it so that the screen was in 2 pieces and you could use it as 2 separate panels instead of having to use it as one big panel. It says 2 panel folding privacy screens, but it's really one big one that folds in the middle.
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Reviewed in the United States on May 25, 2026
M
Verified Purchase
Melinda
Lowell, US
★★★★★ 5
sturdy & attractive
Color: Natural, Size: 4 Panel
excellent look and sturdy
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Reviewed in the United States on May 24, 2026
R
Verified Purchase
Ramon Ray
Alexandria, US
★★★★★ 5
Good product
Color: Brown, Size: 8 Panel
It is made well. It is longer than I expected which was good.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 17, 2026

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