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Description
Biotin Rat Anti-Mouse Ly6G Antibody (S-R481)Product Specification Host Rat Antigen Ly6G Synonyms Lymphocyte antigen 6G; Ly 6G; Ly 6G. 1; Ly6g Location Cell membrane Accession P35461 Clone Number S R481 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample BALB c mouse bone marrow Purification Protein G Concentration 0. 05mg ml Conjugation Biotin Physical Appearance Liquid Storage Buffer PBS pH7. 4, 0. 03% Proclin 300 Stability & Storage 12 months from date of
Product Specification
| Host | Rat |
| Antigen | Ly6G |
| Synonyms | Lymphocyte antigen 6G; Ly-6G; Ly-6G.1; Ly6g |
| Location | Cell membrane |
| Accession | P35461 |
| Clone Number | S-R481 |
| Antibody Type | Rat mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | BALB/c mouse bone marrow |
| Purification | Protein G |
| Concentration | 0.05mg/ml |
| Conjugation | Biotin |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
Ly6G (Lymphocyte antigen 6 complex, locus G6D) is a 21-25 kD glycosylphosphatidylinositol (GPI)-anchored protein and a member of the Ly-6 superfamily, predominantly expressed on myeloid-derived cells such as neutrophils, granulocytes, and monocytes. It serves as a key marker for identifying and distinguishing these cell populations, especially neutrophils, due to its tightly regulated expression during cell differentiation and maturation. In addition to its role as a cell surface marker, Ly6G is involved in cell signaling and adhesion processes. It has also been implicated in various immunological studies, including antitumor responses and the modulation of immune cell functions in both normal and pathological conditions.
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