SKU: 86581031275

Alexa Fluor® 488 Mouse Anti-Human CD25 Antibody (S-3536)

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Description

Alexa Fluor® 488 Mouse Anti-Human CD25 Antibody (S-3536)Product Specification Host Mouse Antigen CD25 Synonyms Interleukin 2 receptor subunit alpha; IL 2 receptor subunit alpha; IL 2 RA; IL 2R subunit alpha; IL2 RA; TAC antigen; p55; IL2RA Location Membrane Accession P01589 Clone Number S 3536 Antibody Type Mouse mAb Isotype IgG1 Application FCM Reactivity Hu Positive Sample PHA stimulated human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid

Product Specification


Host Mouse
Antigen CD25
Synonyms Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; IL2RA
Location Membrane
Accession P01589
Clone Number S-3536
Antibody Type Mouse mAb
Isotype IgG1
Application FCM
Reactivity Hu
Positive Sample PHA stimulated human PBMC
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD25, also known as IL2RA, is the alpha chain of the interleukin-2 receptor, a heterotrimeric protein complex that also includes beta (IL2RB) and the common gamma chain (IL2RG). It is a membranous glycoprotein primarily expressed on activated T lymphocytes and plays a crucial role in immune homeostasis by interacting with interleukin-2, a pleiotropic cytokine. CD25 is involved in the proliferation of T and B lymphocytes and is essential for the assembly of the high-affinity interleukin-2 receptor. In addition to its role in the immune system, CD25 is also expressed on certain non-immune cells and has been identified as a potential therapeutic target in cancers.

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SKU: 86581031275

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