Pay in installments of $30.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 26 - Jul 31
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Human TIMP2 Protein, His TagProduct Specification Species Human Synonyms Metalloproteinase inhibitor 2, CSC 21K, Tissue inhibitor of metalloproteinases 2 (TIMP 2) Accession P16035 Amino Acid Sequence Protein sequence (P16035, Cys27 Pro220, with C His Tag) CSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP Expression System HEK293
Product Specification
| Species | Human |
| Synonyms | Metalloproteinase inhibitor 2, CSC-21K, Tissue inhibitor of metalloproteinases 2 (TIMP-2) |
| Accession | P16035 |
| Amino Acid Sequence | Protein sequence (P16035, Cys27-Pro220, with C-His Tag) CSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP |
| Expression System | HEK293 |
| Molecular Weight | Predicted MW: 23.4 kDa Observed MW: 20-25 kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
TIMP2 (Tissue Inhibitor of Metalloproteinases 2) is a key regulatory protein belonging to the TIMP family, which inhibits matrix metalloproteinases (MMPs) to maintain extracellular matrix (ECM) homeostasis. By controlling MMP activity, TIMP2 plays a critical role in tissue remodeling, wound healing, and inflammation. Beyond its inhibitory function, TIMP2 exhibits MMP-independent activities, such as modulating cell growth, differentiation, and angiogenesis. It is also involved in pathological processes, including cancer progression and fibrosis, where its dysregulation contributes to ECM degradation or excessive deposition.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy