SKU: 8526506327

α-Actinin-1 Recombinant Rabbit mAb (SDT-311-20)

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Description

α-Actinin-1 Recombinant Rabbit mAb (SDT-311-20)Product Specification Host Rabbit Antigen Actinin 1 Synonyms Alpha actinin 1, ACTN1 Immunogen Synthetic Peptide Location Cytoplasm, Cytoskeleton, Cell membrane Accession P12814 Clone Number SDT 311 20 Antibody Type Rabbit mAb Application WB, IHC P Reactivity Hu, Ms, Rt Predicted Reactivity Bv, Mq Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability &

Product Specification


Host Rabbit
Antigen α-Actinin-1
Synonyms Alpha-actinin-1, ACTN1
Immunogen Synthetic Peptide
Location Cytoplasm, Cytoskeleton, Cell membrane
Accession P12814
Clone Number SDT-311-20
Antibody Type Rabbit mAb
Application WB, IHC-P
Reactivity Hu, Ms, Rt
Predicted Reactivity Bv, Mq
Purification Protein A
Concentration 0.5 mg/ml
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, -20 °C as supplied.

Dilution


application dilution species
WB 1:1000-1:5000
IHC-P 1:2000

Background

Alpha-actinin (α-actinin) is a ubiquitous cytoskeletal protein, which belongs to the superfamily of filamentous actin (F-actin) crosslinking proteins. It is present in multiple subcellular regions of both muscle and non-muscle cells, including cell-cell and cell-matrix contact sites, cellular protrusions and stress fiber dense regions and thus, it seems to bear multiple important roles in the cell by linking the cytoskeleton to many different transmembrane proteins in a variety of junctions. Four isoforms of human α-actinin have already been identified namely, the "muscles" α-actinin-2 and α-actinin-3 and the "non-muscles" α-actinin-1 and α-actinin-4 [PMID: 21241830]. α-actinin-1 is an important intracellular calcium-sensing protein, the major actin crosslinking protein in focal adhesions and stress fibers [PMID: 27272015].

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SKU: 8526506327

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DDD Projects
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★★★★★ 5
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I am a big fan of Bruno Marc shoes. Over the years they have provided comfortable and affordable boots and shoes. These blue, tan and white soled dress sneakers are no exception. They have a nice finished look that makes them both causal and dressy. The lightweight style is still warm enough for colder mid-west winters. The box of the toes is wide and comfortable. The insole is well padded and a pleasure to wear. This is another fine pair of shoes to add to my collection and yours.
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Reviewed in the United States on January 14, 2026
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Massapequa, US
★★★★★ 5
Must buy: Comfort + Casual + Well Made / Ventilated
Size: 8, Color: Brown
Just buy it! I have put in roughly 15,000 steps in this shoes in 10 days and I can't believe how comfortable they are after this much rough use in short amount of time. I highly recommend this shoes to anyone looking for comfort in casual style.
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Reviewed in the United States on May 4, 2026
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William W.
Port Orchard, US
★★★★★ 5
WIDE Dress Shoes With SUPPORT
Size: 10.5, Color: Brown
I've seen dress shoes and worn dress shoes before, but these are simply the best dress shoes I've ever worn my entire life. 99% of dress shoes have the same problem, they have the thinnest little soles that offer no support. BRUNO MARC HAS SOLVED THE PROBLEM. These dress shoes not only support wide feet like mine who historically have had and still have little support in the market, but Bruno Marc has wide options that fit perfectly, and the support with the thick foam sole is so needed and awesome. I had a pleasant surprise putting these things on and there being some tactile grip enhancers inside the shoe so you can feel the shoes better and get a little tickle / massage while you're at it. These things are dripping with style, easy to wear, and while they might look firm on the outside, on the inside the shoe just has such a nice flexibility and foamy feel, the top where the top of your feet feel the roof of the shoe, it has such perfect ooey gooey support I can't believe it. The outside sole also has this neat tactile feel. The durability looks good and feels good for now.
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Reviewed in the United States on September 28, 2025
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New York, US
★★★★★ 5
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Size: 10, Color: Cognac
Love these shoes super comfortable and look great. Everyone asks me where I got them.
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Reviewed in the United States on May 20, 2026
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Amazon Customer
Pawtucket, US
★★★★★ 5
Beautiful shoe but too narrow
Size: 10 Wide, Color: Navy Grainy Leather
Too narrow
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Reviewed in the United States on May 24, 2026

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