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Description
IL-17A Protein, RatProduct Specification Species Rat Synonyms Interleukin 17A,IL 17,IL 17A,Cytotoxic T lymphocyte associated antigen 8 (CTLA 8) Accession Q61453 Amino Acid Sequence Ala18 Ser150 Expression System HEK293 Molecular Weight 12 22kDa (Reducing) Purity >95% by SDS PAGE; >90% by HPLC; Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to
Product Specification
| Species | Rat |
| Synonyms | Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8 (CTLA-8) |
| Accession | Q61453 |
| Amino Acid Sequence | Ala18-Ser150 |
| Expression System | HEK293 |
| Molecular Weight | 12-22kDa (Reducing) |
| Purity | >95% by SDS-PAGE; >90% by HPLC; |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | ·12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | Int Immunopharmacol. 2023 Oct:123:110757. |
Background
Interleukin 17A (IL-17A) is a major member of the IL-17 cytokine family and is produced mainly by T helper 17 (Th17) cells. In healthy individuals, IL-17A has a host-protective capacity, but excessive elevation of IL-17A is associated with the development of autoimmune diseases and cancer. IL-17A is essential for modulating the interplay between commensal microbes and epithelial cells at our borders (i.e., skin and mucosae), and yet, for protecting us from microbial invaders, thus preserving mucosal and skin integrity.
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