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Description
KGF/FGF-7 Protein, HumanProduct Specification Species Human Synonyms Keratinocyte Growth Factor, Fibroblast Growth Factor 7, HBGF 7 Accession P21781 Amino Acid Sequence Cys32 Thr194 Expression System E. coli Molecular Weight Approximately 18. 9 kDa, a single non glycosylated polypeptide chain containing 163 amino acids. Purity 96% by SDS PAGE or HPLC. Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20 mM PB, with 500 mM NaCl, pH 8.
Product Specification
| Species | Human |
| Synonyms | Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7 |
| Accession | P21781 |
| Amino Acid Sequence | Cys32-Thr194 |
| Expression System | E.coli |
| Molecular Weight | Approximately 18.9 kDa, a single non-glycosylated polypeptide chain containing 163 amino acids. |
| Purity | ＞96% by SDS-PAGE or HPLC. |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20 mM PB, with 500 mM NaCl, pH 8.0. |
| Reconstitution |
Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage | For long term storage, the product should be stored ≤ -20℃. |
Background
KGF (also known as FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF/FGF-7 is a mitogen factor specific for epithelial cells and keratinocytes. KGF/FGF-7 signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, as well as in angiogenesis and wound healing. KGF actives on keratinocytes, and exhibits mitogenic activity for epidermal cells, but essentially no activity for fibroblasts. KGF has species cross active, human KGF shares 96% and 92% amino acid sequence identity with murine and rat FGF-7, respectively. Recombinant Human KGF/FGF-7 is an 18.9kDa protein consisting of 163 amino acid.
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