SKU: 82388143191

Rat Anti-Human CX3CR1 Antibody (S-3020)

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Description

Rat Anti-Human CX3CR1 Antibody (S-3020)Product Specification Host Rat Antigen CX3CR1 Synonyms CX3C chemokine receptor 1; C X3 C CKR 1; Beta chemokine receptor like 1 (CMK BRL 1; CMK BRL1); Fractalkine receptor; G protein coupled receptor 13; V28; CMKBRL1; GPR13 Location Cell membrane Accession P49238 Clone Number S 3020 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Hu Positive Sample Hman PBMC Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical

Product Specification


Host Rat
Antigen CX3CR1
Synonyms CX3C chemokine receptor 1; C-X3-C CKR-1; Beta chemokine receptor-like 1 (CMK-BRL-1; CMK-BRL1); Fractalkine receptor; G-protein coupled receptor 13; V28; CMKBRL1; GPR13
Location Cell membrane
Accession P49238
Clone Number S-3020
Antibody Type Rat mAb
Isotype IgG2b,k
Application FCM
Reactivity Hu
Positive Sample Hman PBMC
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:100 Hu

Background

CX3CR1 (C-X3-C motif chemokine receptor 1) is a G protein-coupled receptor that plays a crucial role in immune cell migration and function. It is primarily expressed on cells such as monocytes, macrophages, and microglia. The ligand for CX3CR1 is CX3CL1 (fractalkine), which can exist both as a membrane-bound form and a soluble form. The interaction between CX3CR1 and CX3CL1 is essential for maintaining immune homeostasis in tissues. In the central nervous system, CX3CR1 on microglia helps regulate their surveillance and response to neuronal damage or infection. Additionally, in peripheral tissues, CX3CR1 signaling is involved in the recruitment of immune cells to sites of inflammation. Dysregulation of the CX3CR1 pathway has been implicated in various inflammatory and neurodegenerative diseases, making it a potential therapeutic target for conditions such as multiple sclerosis, Alzheimer's disease, and cardiovascular diseases.

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SKU: 82388143191

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4.4 ★★★★★
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Product Reviews
R
Rudi van den Berg
Waukegan, US
★★★★★ 5
Great Reference
Format: Hardcover
The book provides a complete, high-level overview of Project Portfolio Management (PPM). As the title suggests, it covers both Portfolio Management and Project Management. The book is a great reference for PPM concepts. I personally found the first few chapters of the book very interesting, because it talks about portfolio management in a different manner than what you would read in other books such as PMI's The Standard for Portfolio Management. The book has been written in an easy-to-read style and it provides pragmatic ideas on how to best help an organization manage their portfolio, using concepts such as: Anchoring, superior estimation, batch vs. ad hoc prioritization, one portfolio or many, private collection of information, winner's curse, innovation vs. improvement projects, accounting vs. project management, etc. In short, the book is a recommender for all PPM practitioners!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on October 28, 2009
E
Emily B. Cherkin
Chelsea, US
★★★★★ 4
Great introduction to work management
Format: Hardcover
I am not an expert in project or work management and found this book really useful and readable. Moore does a great job of looking beyond standard project management terms and frameworks and helps re-frame project management as a strategic, not a tactical concern.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on October 23, 2009
A
Verified Purchase
Andrea Cercado
Fort Morgan, US
★★★★★ 5
Nice update
Format: Paperback, Format: Paperback
I really like this version of a practice test. It covers pretty much all the topics I wanted to learn more about (like math related) and the fact that’s it’s current for this year is great. I didn’t want to practice with old information. It also has a well-structured approach to mastering the digital format. I feel like it properly prepares you for the actual feeling of doing the test. My favorite thing has to be the mini test. Sometimes I think I’m ready for a test but end up realising I still have a long way to practice so it’s great to have a tool that helps with that. Just overall, its practice is very reasonable so as long as you take the time to really take advantage of this book, the SAT will be a breeze.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 11, 2025
C
Verified Purchase
Charlene Hernes
Chelsea, US
★★★★★ 5
An exceptional resource
Format: Paperback, Format: Paperback
Vibrant Publishers did a great job on writing this SAT book. It has been researched thoroughly. Vibrant publishers has some great study lessons in here that gives great ideas for helping others with learning the SAT. The lessons are great to learn, and also the questions to study are very easy to understand and put the answers in context to answer the questions. This book I would definitely recommend to others given the chance. I hope to hear more from the author. The author made it easy to learn and study for the SAT. Vibrant publishers gave some great ideas on how to help students study for the SAT. I think there are some great ideas to helping people pass the test to go to college, and do well. I definitely give this book a 5-star rating.
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Reviewed in the United States on March 1, 2025
S
Verified Purchase
Sachi
Houston, US
★★★★★ 4
Will definitely help with preparedness
Format: Paperback, Format: Paperback
When I was first planning on taking the SAT, I definitely underestimated how to be prepared. I wish I had a book like this one back then. This book has really put together a comprehensive way of getting prepared for such an important exam. Not only are there practice exams, there is also a way to estimate your actual test scores so that you can see what areas need work. Also, there are so many different variations of questions that it will really prepare your mind for the actual exam. Better than most practice test books out there.
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Reviewed in the United States on March 12, 2025

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