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Description
SLFN5 Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen SLFN5 Synonyms Schlafen family member 5 Immunogen Recombinant Protein Location Nucleus Accession Q08AF3 Antibody Type Polyclonal antibody Isotype IgG Application WB, ICC Reactivity Hu Positive Sample A549, T 47D, LNCaP, A431 Purification Immunogen Affinity Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability &
Product Specification
| Host | Rabbit |
| Antigen | SLFN5 |
| Synonyms | Schlafen family member 5 |
| Immunogen | Recombinant Protein |
| Location | Nucleus |
| Accession | Q08AF3 |
| Antibody Type | Polyclonal antibody |
| Isotype | IgG |
| Application | WB, ICC |
| Reactivity | Hu |
| Positive Sample | A549, T-47D, LNCaP, A431 |
| Purification | Immunogen Affinity |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
| ICC | 1:500 | Hu |
Background
SLFN5 (Schlafen family member 5) is a protein-coding gene that belongs to the Schlafen family, which is involved in various biological processes such as cell cycle regulation, immune response, and viral infection. SLFN5 has been identified as a regulator of cell motility and invasion in renal cell carcinoma, and its expression is associated with poor prognosis in colorectal adenocarcinoma. Additionally, SLFN5 acts as a restriction factor against herpes simplex virus type 1 (HSV-1) infection by suppressing viral transcription. It is also regulated by the androgen receptor in castration-resistant prostate cancer.
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