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Description
Phospho-Akt (Ser473) Recombinant Rabbit mAb (S-622-64)Product Specification Host Rabbit Antigen Phospho Akt (Ser473) Synonyms RAC alpha serine threonine protein kinase, Protein kinase B (PKB), Protein kinase B alpha (PKB alpha), Proto oncogene c Akt, RAC PK alpha, PKB, RAC, AKT1 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus, Cell membrane Accession P31749 Clone Number S 622 64 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC, ICFCM, IP Reactivity Hu Predicted Reactivity Rt, Ms
Product Specification
| Host | Rabbit |
| Antigen | Phospho-Akt (Ser473) |
| Synonyms | RAC-alpha serine/threonine-protein kinase, Protein kinase B (PKB), Protein kinase B alpha (PKB alpha), Proto-oncogene c-Akt, RAC-PK-alpha, PKB, RAC, AKT1 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus, Cell membrane |
| Accession | P31749 |
| Clone Number | S-622-64 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC, ICFCM, IP |
| Reactivity | Hu |
| Predicted Reactivity | Rt, Ms |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| ICC | 1:500 | |
| ICFCM | 1:500 | |
| Dot Blot | 1:1000 | |
| IP | 1:50 |
Background
Akt or Protein kinase B, is a serine/threonine kinase that plays an important role in regulating a number of cellular processes such as growth, metabolism and survival. The importance of the Akt pathway is highlighted by the mutation of various components of the pathway in human cancers such as the PTEN and PI3-kinase (P110α), which occur in more than 30% of human tumors. For Akt to achieve full activation, phosphorylation is needed at both serine 473 (ser473) of the hydrophobic tail and threonine 308 (thr308) of the activation motif, upon growth factor ligation to the receptor tyrosine kinases.
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4.6 ★★★★★
Based on 12 reviews
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Product Reviews
★★★★★ 5
Very Good Godot Book
Format: Paperback
Great book overall!
Best suited for beginners as it literally begins by conceptually introducing variables, operators, etc. Still, it's very Godot. And nicely up-to-date as well, focusing on Godot 4.x and GDScript 2. Note though that the book only covers 2D, which is a shame. Hopefuly, the author is hard at work on a text thast starts where this one ends and moves on to explore 3D in Godot.
The illustrations are little muddy, but fortunately, Packt offers free downloads of (much crisper) PDFs with proof of purchase.
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Reviewed in the United States on May 25, 2024
★★★★★ 5
Book Review: "Learning GDScript with Godot 4
Format: Kindle, Format: Kindle
Learning GDScript with Godot 4" is an invaluable resource for both beginners and those looking to solidify their understanding of Godot's scripting language. This comprehensive guide takes you from the very basics to creating portfolio-worthy projects, making it a perfect starting point for aspiring game developers.
One of the book's standout features is its in-depth approach. It covers the fundamentals thoroughly, ensuring that readers build a strong foundation in GDScript. The inclusion of numerous code examples is particularly beneficial, providing practical insights into how to implement various features and mechanics within Godot 4.
Visual learners will appreciate the thoughtfully placed pictures throughout the book. While not overly abundant, these visuals effectively complement the text, helping to clarify complex concepts and enhance understanding.
Despite Godot's increasing support for C#, the focus on GDScript in this book is well-justified. GDScript is tightly integrated with Godot, making it an excellent choice for rapid development and learning. The book's code-centric approach ensures that readers gain hands-on experience, which is crucial for mastering any programming language.
Overall, "Learning GDScript with Godot 4" is an excellent resource for anyone looking to learn or deepen their knowledge of GDScript and Godot 4. Its thorough coverage, practical examples, and supportive visuals make it a must-have for your game development library. Whether you're a complete beginner or looking to fill in gaps in your knowledge, this book will guide you every step of the way.
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Reviewed in the United States on May 28, 2024
★★★★★ 5
An Excellent Introduction to Game Programming using GDScript/Godot
Format: Paperback
You’ll get up and going quickly with an overview of Godot and then jump straight into GDScript by learning about variables, control flow, collections, loops, object-oriented programming, and concepts like DRY, KISS, etc. Then the fun begins by building game mechanics while learning specifics of Godot such as the node/scene system, reusing scenes, cameras, collision detection, creating user interfaces, and more.
It also covers local multiplayer where you'll learn the basics of computer networking followed by learning about built-in multiplayer nodes provided by Godot. The final chapters cover some advanced programming patterns like event bus, object pooling, and state machines. By the end, you’ll have a fully playable single/local multiplayer game in the style of Vampire Survivors!
I thoroughly enjoyed my time with this book and highly recommend it for anyone who wants to get started on their journey to learn programming and even for experienced game programmers who want to learn Godot and GDScript.
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Reviewed in the United States on May 19, 2024
★★★★★ 4
Fine so far.
Format: Paperback
I am looking for some of the code from exercises, but can't find it in the project files, and they say don't copy it from the ebook...?
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Reviewed in the United States on November 17, 2024
★★★★★ 5
Very comprehensive and approachable
Format: Kindle
This e-book covers everything starting from basic general programming concepts and Godot development, going into (relatively) advanced game development programming patterns that are used throughout the industry. It explains not only what the best practices are but why they are used in a simple and understandable way, and provides points of reflection and knowledge testing with quiz sections.
I highly recommend this book for anyone wanting to learn game development as a hobby, anyone interested in learning Godot, and even for anyone trying to learn game programming in general and wanted a simple place to start.
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Reviewed in the United States on June 11, 2024