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Gain of FunctionBy: Nicholas G. Evans Series: The MIT Press Essential Knowledge series How a small number of risky experiments creates many unwieldy problems for life science research. The life sciences have never been more critical to human health, wealth, and security. But with any endeavor comes risk, and the last decade has seen concerns raised about gain of function research in which a microbe, usually a virus, is given new properties like enhanced lethality,
By: Nicholas G. Evans | Series: The MIT Press Essential Knowledge seriesHow a small number of risky experiments creates many unwieldy problems for life science research.
The life sciences have never been more critical to human health, wealth, and security. But with any endeavor comes risk, and the last decade has seen concerns raised about gain-of function-research in which a microbe, usually a virus, is given new properties like enhanced lethality, transmissibility, or the capability to infect new species. In 2021 the term seeped into the tabloids when a conflict between Senator Rand Paul and Dr. Anthony Fauci arose over the origins of COVID-19. In Gain of Function, Nicholas Evans—who has spent his career studying gain-of-function research—describes what this kind of research is, what it isn’t, and why a small number of scientific experiments continues to make headlines.
Evans begins with a description of what gain-of-function research is in science, and what it means in government policy. He tells the story of the original papers that sparked controversy more than a decade ago, unpacking them for readers unfamiliar with virology research, and he identifies where and why policymakers and scientists alike became concerned. He then turns to the history of policies that attempt to regulate gain-of-function research, the current controversies, and the ethics of risky research. He concludes with the future of gain of function, including how debates about gain of function will influence science and public health in years to come.
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4.3 ★★★★★
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Product Reviews
★★★★★ 5
K270 keyboard info that might help you
Color: Black, Size: 1 Pack, Style: Keyboard
This review is a bit long, but has info that might help you. I posted it twice, once for the K270 keyboard and once for the M510 mouse. I have owned a K270 keyboard and M185 compact mouse for years. I bought them as the keyboard/mouse combo that Logitech sells. I have been happy with them. They are still working, but I decided that I would like to have a full size mouse. I settled on the M510 for the new mouse. The M510 mouse works with the unifying receiver. I did a fair amount of research before buying. I thought I could use the original K270 keyboard with the new mouse. I found that the older M185 mouse is not unifying. I thought that was odd because when you look at the seperate K270 Keyboard, it says that it is a unifying keyboard. Why would the combo set have a unifying keyboard but a non-unifying mouse? From what I have read online, when you buy the K270/M185 combo, it is NOT a unifying set. If you buy the K270 keyboard seperately, it IS a unifying keyboard. Since I wanted to get the M510 mouse, I had to buy a new seperate K270 keyboard since the one in the combo set is not unifying. I found this out ahead of time, so it was not an issue. I actually bought 2 each of the K270 & M510, for each of our 2 computers. Did not have any trouble getting them up and running. As a side benefit, the keyboard and mouse each come with a unifying receiver so I have a couple of spare receivers now. Registering them was an adventure. There are two methods to register, a serial number search or entering the info manually. The serial number search did not find any of them, so I did it manually. I did the keyboards first. After you enter the info for the unit you are registering, the registration software asks for the serial number. When you give it the serial number, I does a serial number search and verifies that the serial number matches that unit. This serial number search acutally worked (sort of). It found one of the keyboards correctly, but kept changing the other to a K295 instead of a K270. More on that in a bit. Next I registered the mice. When I got to the point where you select the correct model, the M510 was not in the list. I tried a few different things and finally found a trick that worked. When it asked for the model, I used M525 instead of M510. At the next step where it did the serial number search, it found the serial number was associated with the M510 and corrected the model entry from M525 to M510. Success with the mice. Back to the keyboard. I could not figure out a way around the registration error, so I contacted Logitech support and got a reply back from a support rep named Sharan. After a couple of email exchanges, Sharan was able to get the other keyboard registered correctly - Thank you again for your help, Sharan. I had noticed when I first started all of this that each unit has two serial numbers, one on the box and one on the unit. The two serial numbers did not match. Sharan told me that the number on the box is strictly for inventory use and the number on the unit is the one to use when registering. Anyway, both sets are now working and correctly registered. Happy with the purchase.
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Reviewed in the United States on January 30, 2024
★★★★★ 5
Easy and Works Great
Color: Black, Size: 1 Pack, Style: Combo
This is perfect, works great, and so easy to connect. Just plug in USB and it's ready.
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Reviewed in the United States on May 3, 2026
★★★★★ 5
Lovely
Color: Rose, Size: 1 Pack, Style: Combo
Love the clacking sound, it’s satisfying, the keys aren’t sticky, it’s a nice shade of pink, comfortable to use. Keys pop off easy enough for easy cleaning and are super stable when popped back on. The mouse is great two, it’s a two-in-one set up with the USB plug in so it controls both which is nice.
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Reviewed in the United States on May 27, 2026
★★★★★ 4
An extra separate dongle for the keyboard and mouse would make this perfect.
Color: Off White, Size: 1 Pack, Style: Combo
I picked up the Logitech MK270 Wireless Keyboard and Mouse Combo on a recommendation from our IT guy, and overall it’s been a solid buy for the price.
The keyboard is the highlight. I’ve been using it for a couple of weeks now and it’s been great. It’s quiet, responsive, and just works every time without any issues. Setup was simple and I haven’t had a single connectivity problem. I do wish the rear feet lifted it a bit higher. Even fully extended, it sits more flat than what I was used to. That said, I’m adjusting to it and it hasn’t been a dealbreaker.
The mouse is where it falls short. It gets the job done, but it definitely feels a bit cheap compared to the keyboard. Lightweight in a way that doesn’t feel premium, and just not the same level of quality overall.
One thing I really wish they included is a second dongle. I’d love to keep the keyboard connected to my main PC and use the mouse with my laptop, but with only one receiver that’s not an option out of the box.
All in, this is a reliable combo from Logitech. The keyboard alone makes it worth it, especially at this price point. Just go in knowing the mouse is pretty basic and you’re limited to a single receiver setup.
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Reviewed in the United States on April 22, 2026
★★★★★ 5
Perfect solution to a common problem
Size: 6-Foot Cable, Style: Rotating Plug - Single Pack
Power strips that have low profile plugs are fairly easy to find these days, but it's a lot more difficult to find one where the cord leaves the plug in the direction you need it to. This solves that problem. you can turn the prongs on the plug and any direction you need them to go. And it doesn't hurt that the design is attractive and appears to be fairly sturdy. I've been using mine for over a month at this point and I'm very happy with it.
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Reviewed in the United States on September 9, 2025