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Description
Biotinylated LAIR1 Fc&Avi Tag Protein, HumanProduct Specification Species Human Synonyms LAIR1, CD305 Accession Q6GTX8 Amino Acid Sequence Gln22 His163, with C terminal human IgG Fc & Avi Tag
Product Specification
| Species | Human |
| Synonyms | LAIR1, CD305 |
| Accession | Q6GTX8 |
| Amino Acid Sequence | Gln22-His163, with C- terminal human IgG Fc & Avi Tag QEEDLPRPSISAEPGTVIPLGSHVTFVCRGPVGVQTFRLERESRSTYNDTEDVSQASPSESEARFRIDSVSEGNAGPYRCIYYKPPKWSEQSDYLELLVKETSGGPDSPDTEPGSSAGPTQRPSDNSHNEHAPASQGLKAEHIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKGLNDIFEAQKIEWHE |
| Expression System | HEK293 |
| Molecular Weight | 55-60kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Biotin |
| Tag | Human Fc Tag, Avi Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Meyaard L. et al. (2001) The epithelial cellular adhesion molecule (Ep-CAM) is a ligand for the leukocyte-associated immunoglobulin-like receptor (LAIR). J Exp Med. 194(1): 107-112. 2、Xu M. et al. (2000) Identification and characterization of leukocyte-associated Ig-like receptor-1 as a major anchor protein of tyrosine phosphatase SHP-1 in hematopoietic cells. J Biol Chem. 275(23): 17440-6. |
Background
Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is a type I glycoprotein of 287 amino acids containing a single extracellular Ig-like domain followed by a stalk region connected to the single transmembrane domain and 2 cytoplasmic immunoreceptor tyrosine-based inhibitory motifs that relay the inhibitory signal. LAIR-1 is expressed on almost all immune cells, including NK cells, T cells, B cells and mono-cytes, monocyte-derived dendritic cells, eosinophils, and basophils and mast cells. LAIR-1 binds both transmembrane and extracellular matrix collagens. The mLAIR-1 gene maps to the proximal end of mouse chromosome 7 in a region syntenic with human chromosome 19q13.4 where the LRC is located. LAIR-1 are involved in controlling the balance of the immune system to prevent improper activation or overactivation, which may result in tissue damage or autoimmune diseases. LAIR1 has been shown to inhibit T and NK cell activation mediated by several activating receptors. Furthermore, it has been shown that LAIR1 can deliver an inhibiting signal on intracellular free calcium concentration and immunoglobulin (Ig) production induced by the engagement of B cell antigen receptors (BCR).
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4.1 ★★★★★
Based on 22 reviews
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Product Reviews
★★★★★ 5
Solid case.
Color: Sky-Blue
Love this case. Fits great and the color is great! The keyboard is nice and it even has a little spot for a stylist.
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Reviewed in the United States on June 3, 2026
★★★★★ 4
Cheap and good
Color: Black, Color: Black
I chose the color black and it gives a really nice look, especially with the multicolor led lights around the keys. It is very easy to clean and you can shut off the keyboard to prevent any mess with the iPad. The magnet is very nice and keeps the keyboard in place. The keyboard doesn’t easily slip or anything so it holds the iPad very well. Only bad thing is that over time the iPad begins to scrape off the pain and it leaves your keyboard with some white spots all over :/ but if looks isn’t something that you care about, this is the keyboard for you. Don’t use it for gaming because there is a delay in functionality when you press a key and then try to use the pad. Also, you have to press the keys a bit harder than the usual keyboard. But for the price? This is a great item! Definitely worth my money
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Reviewed in the United States on January 18, 2026
★★★★★ 5
Great quality at a remarkable price
Color: Navy Blue
I got an iPad and was looking for a cover to protect it. I came across this case that has a Bluetooth keyboard. It seems to be working great. It was less than $30 and had 4.5 stars with over 4k reviews.
The keyboard is magnetic and detachable, so I’ve got lots of configuration options. The keyboard pairs easily and allows you to use the iPad like a laptop. The point of an iPad a lot in one shot is kind of the touchscreen, but when I’m typing a lot of text as once (like now), it’s really nice to have a physical keyboard and touchpad. The keys are comfortably spaced and I’m comfortable typing on it. There is no additional setup for the keyboard besides pairing it to the iPad. At that point, all the cursor and keyboard features are immediately available.
The case is well built and has nice features like a slot to hold a stylus and multiple grooves to set your viewing angle. It’s configured to be used in landscape mode, but if for some reason you wanted to use it in portrait mode, you can pop the keyboard off to lay it flat. Especially for the price, this is an exceptionally nice iPad cover.
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Reviewed in the United States on May 8, 2026
★★★★★ 5
💪🏼💪🏼🇺🇸🇺🇸🇺🇸
Color: Navy Blue
⭐️⭐️⭐️⭐️⭐️
Very high-quality product, ideal for all types of heavy-duty work. It feels strong, comfortable, and durable. It performs its function perfectly and exceeds expectations. I highly recommend it for its excellent performance and great value for the pr
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Reviewed in the United States on May 10, 2026
★★★★★ 5
Pink IPad Case
Color: Pink
Great case. My iPad feels very safe in this case compared to my other ones. Easy to clean and the color matches the picture.
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Reviewed in the United States on June 8, 2026