SKU: 76384169650

MICB Recombinant Rabbit mAb (SDT-1472-102)

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Description

MICB Recombinant Rabbit mAb (SDT-1472-102)Product Specification Host Rabbit Antigen MICB Synonyms MHC class I polypeptide related sequence B; MIC B; Immunogen Recombinant Protein Accession Q29980 1 Clone Number SDT 1472 102 Antibody Type Recombinant mAb Isotype IgG Application Sandwich ELISA Reactivity Hu Cross Reactivity No cross reactivity against MICB, NKG2D Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4, 0. 03%

Product Specification


Host Rabbit
Antigen MICB
Synonyms MHC class I polypeptide-related sequence B; MIC-B;
Immunogen Recombinant Protein
Accession Q29980-1
Clone Number SDT-1472-102
Antibody Type Recombinant mAb
Isotype IgG
Application Sandwich ELISA
Reactivity Hu
Cross Reactivity

No cross-reactivity against MICB, NKG2D

Purification Protein A
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt, 2 to 8 °C as supplied

Background

MHC I polypeptide-related sequence B (MICB) is a highly glycosylated transmembrane protein encoded by the MICB gene, located on chromosome 6p21.33. It functions as a ligand for the NKG2D receptor, a type II receptor expressed on natural killer (NK) cells, CD8+ T cells, and γδ T cells. The binding of MICB to NKG2D activates cytolytic responses in these immune cells, promoting the elimination of stressed or infected cells. Unlike MHC class I molecules, MICB does not associate with β-2-microglobulin or bind peptides. MICB is stress-induced, meaning its expression increases under cellular stress conditions, such as DNA damage or viral infection. This protein is widely expressed in various tissues, including lymph nodes and bone marrow, highlighting its role in immune surveillance. The external domains of MICB are proteolytically cleaved by surface proteases and shed into the extracellular space. MICB shedding by cancer cells causes effective escape from NKG2D recognition and allows the development of cancers. Patients frequently have increased concentrations of soluble MICA/B molecules shed in the blood plasmas and sera, thus indicating that MICA/B shedding is a therapeutic target in immune-oncology.

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SKU: 76384169650

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Katherine
San Leandro, US
★★★★★ 5
Great suit!
Color: Black, Size: Medium
Looks super nice! For the price, it is definitely worth it. The fabric looks and feels great and the size range is good.
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Reviewed in the United States on May 9, 2026
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Kia
Whiting, US
★★★★★ 5
​Perfect for a wedding! Everyone loved it
Color: Deep Blue, Size: XX-Large
​I bought this suit set for our wedding and it was a huge hit everyone loved how it looked! The slim fit is perfect and looks very sharp and modern. The material is great quality and it comes with everything you need, making it an incredible value. My kids got compliments all night!
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Reviewed in the United States on May 20, 2026
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S Perez
Houston, US
★★★★★ 5
Great quality
Color: Black, Size: X-Small
Fit my son perfect. Ordered XS he’s 5’5” 128 lbs. pants fit great, they weren’t too big or too long. He felt comfortable and got many complements. Tie color comes random not black like the picture.
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Reviewed in the United States on May 19, 2026
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Travis Avery
Louisville, US
★★★★★ 4
Waist is big. I weigh 238lbs. And got what said was 215-230lb.
Color: Black, Size: XX-Large
Everything fits good, except the waist was about 2-3 sizes to big.
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Reviewed in the United States on May 10, 2026
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Vaifro Dordetto Jr
Battle Creek, US
★★★★★ 5
Great value for a one-time event! Perfect for graduation.
Color: Black, Size: Large, Color: Black, Size: Large
I bought this suit for my son's graduation, and it was exactly what we needed. Since he will probably only wear it once, I didn't want to spend a fortune at a high-end department store. For the price, the quality is surprisingly good; it looked sharp and he received a lot of compliments during the ceremony. We ordered a size Large (L) based on their sizing chart, and it was true to size and fit him perfectly. The fabric is lightweight but doesn't look cheap at all, making this a fantastic, excellent cost-benefit choice if you are looking for an option for a one-time event. Highly recommended!
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Reviewed in the United States on May 18, 2026

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