SKU: 75335478975

Mouse Anti-Rat CD161 Antibody (S-R628)

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Description

Mouse Anti-Rat CD161 Antibody (S-R628)Product Specification Host Mouse Antigen CD161 Synonyms Killer cell lectin like receptor subfamily B member 1A; NKR P1A; Antigen 3. 2. 3; CD161 antigen like family member A; Natural killer cell surface protein P1 3. 2. 3 (NKR P1 3. 2. 3); CD161a; Nkrp1a; Klrb1a Location Membrane Accession P27471 Clone Number S R628 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Rt Positive Sample SD Rat splenocytes Purification Protein G

Product Specification


Host Mouse
Antigen CD161
Synonyms Killer cell lectin-like receptor subfamily B member 1A; NKR-P1A; Antigen 3.2.3; CD161 antigen-like family member A; Natural killer cell surface protein P1-3.2.3 (NKR-P1 3.2.3); CD161a; Nkrp1a; Klrb1a
Location Membrane
Accession P27471
Clone Number S-R628
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Rt
Positive Sample SD Rat splenocytes
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4
Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 1:2000 Rt

Background

CD161, also known as KLRB1 or NKRP1A, is a C-type lectin-like receptor primarily expressed on the surface of natural killer (NK) cells and a subset of T cells, including mucosal-associated invariant T (MAIT) cells and some CD8+ T cells. It is particularly enriched in immune cells located in mucosal sites such as the gut and liver. CD161 binds to its ligand, lectin-like transcript 1 (LLT1, also known as CLEC2D), and this interaction can have both inhibitory and costimulatory effects on immune cells. In the context of cancer immunotherapy, CD161 has been identified as a potential inhibitory receptor in glioma-infiltrating T cells. Its activation by CLEC2D on tumor or immunosuppressive cells can dampen T cell responses against cancer cells. Recent studies suggest that blocking the CD161-CLEC2D interaction may enhance T cell-mediated antitumor activity, making CD161 a promising target for cancer immunotherapy.

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Exchange/Return Notes
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SKU: 75335478975

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4.9 ★★★★★
Based on 22 reviews
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Product Reviews
A
Verified Purchase
Ask Angie
Battle Creek, US
★★★★★ 5
Cute chew toy for smaller dogs!
Color: Red, Color: Red
Soooo my new puppy Dottie was continually eating my favorite pair of crocs by sneaking into my closet. To solve this issue I thought I would buy her her own chewy croc and actually found one on Amazon! lol The chew toy is actually heavy and weighted and the material is hard enough for an effective teething toy but soft enough for the puppy to play with! My little Weeney dog loved it the second I took it out of the package! The fake croc chew toy is a very cute design with a fun, bright color. The chew toy material is constructed of durable rubber and will last a long time. I didn't like that it doesn't make noise and is small.. I believe it is better suited for smaller breads to use which was perfect for my puppies needs.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 24, 2025
J
Verified Purchase
JSpears
Carnegie, US
★★★★★ 5
You should have one on standby.
Color: Yellow, Color: Yellow
This product was great for my teething Bully puppy, she, is an aggressive chewer. It gave her relief and kept her busy. In the 6 or 7 weeks that we've had it, it stood the test of time. She would chew 10 or 15 minutes at a time and nap from exhaustion. Overall, several hours of chewing. I must say this toy is not indestructable. In the end it was necessary to remove it and substitute another toy. The bully on the picture looks like a twin of my own pup. I did remove loose slivers and pieces that could be chewed off immediately. I am attaching a pic of the pre-disposal remnants for clarity. This is a tough toy but again, not indestructible.
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Reviewed in the United States on September 8, 2025
T
Verified Purchase
Tyler
Port Orchard, US
★★★★★ 3
Less than 30 min
Color: Blue, Color: Blue
Bought for my 8 month old lab. Dog toy said for aggressive chewers. Wrong! Super cute and feels heavy duty, but not for aggressive chewers.
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Reviewed in the United States on January 14, 2025
M
Verified Purchase
M DePriest
Carnegie, US
★★★★★ 5
Good for aggressive chewers!
Color: Blue
Smelled awful out of the package and it's way heavier that I expected, but it's one of the only toys that my puppy has not shredded to pieces.
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Reviewed in the United States on May 8, 2026
S
Verified Purchase
Sarah Snyder
Chelsea, US
★★★★★ 4
Solid Toy NOT For Small Breeds
Color: Blue, Color: Blue
Bought this for my Pug puppy because he's always chewing on our shoes and dragging them outside and in every which direction. He doesn't really damage them, it's more of just a pain to chase him around and try and actually get the shoe from him because he thinks we're playing. So, I looked on Amazon for a shoe toy and found this. It has a decent rating of 4.2 stars currently and it looks pretty sturdy. Well, when I got it, I realized that it's VERY sturdy. In fact, it's too sturdy; at least for a smaller breed like a pug. I know in the title is says for medium to large dogs, but when I looked at the demensions I thought it would be fine for him. He played with it for a few minutes, but it's just too big and VERY heavy for him. I was actually surprised how heavy it was. So, I decided to weigh it on a scale I have and it came out to 0.83 pounds. I actually thought it would read heavier than that (at least a pound), but that's what the scale said and I did it twice to be sure. So, if you have a small dog like a Pug, I wouldn't recommend this. Definitely a great toy for a German Shepherd or something in that category because of how heavy and thick it is. I'm guessing, even with a large breed of dog, this toy is probably going to last a long time. There's also a hole in the top where you can put peanut butter (or some kind if dog friendly treat) inside, which is really cool. I tried that with him as well, but he just wasn't interested. He's more into the Kong plushies. Anyway, in all, it's a pretty good product. Just not for a small breed dog. I'm giving it 4 stars. As you can see from the photos I uploaded, it's a rather small toy, but it's very solid and chunky. I also took a few pictures with a Pilot G2 pen next to it to better judge the size. Would buy from this seller again though if they had other toys for smaller breed dogs. Thank you. 💟 Sarah 💟
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Reviewed in the United States on March 2, 2026

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