Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 28 - Sep 2
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Uteroglobin Recombinant Rabbit mAb (SDT-2736-46)Product Specification Host Rabbit Antigen Uteroglobin Synonyms Club cell phospholipid binding protein (CCPBP); Club cells 10 kDa secretory protein (CC10); Secretoglobin family 1A member 1; Urinary protein 1 (UP 1; UP1; Urine protein 1); CC10; CCSP; UGB; SCGB1A1 Immunogen Recombinant Protein Location Secreted Accession P11684 Clone Number SDT 2736 46 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IF Reactivity Hu Positive Sample BxPC
Product Specification
| Host | Rabbit |
| Antigen | Uteroglobin |
| Synonyms | Club cell phospholipid-binding protein (CCPBP); Club cells 10 kDa secretory protein (CC10); Secretoglobin family 1A member 1; Urinary protein 1 (UP-1; UP1; Urine protein 1); CC10; CCSP; UGB; SCGB1A1 |
| Immunogen | Recombinant Protein |
| Location | Secreted |
| Accession | P11684 |
| Clone Number | SDT-2736-46 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IF |
| Reactivity | Hu |
| Positive Sample | BxPC-3 |
| Purification | Protein A |
| Concentration | 0.2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500-1:1000 | Hu |
| IHC-P | 1:2000 | Hu |
| IF | 1:200 | Hu |
Background
Uteroglobin, also known as secretoglobin 1A1 or blastokinin, is a small, 70–77 amino acid, disulfide-linked homodimeric protein that is secreted by the Clara (non-ciliated bronchiolar exocrine) cells of the pulmonary airways, the epithelial cells of the endometrium and the prostate, and is found in high concentrations in the uterine fluid of rabbits and other mammals during early pregnancy, where it functions as a potent anti-inflammatory, immunomodulatory, and anti-fibrotic agent by binding and sequestering hydrophobic ligands such as phospholipids, prostaglandins, and the lipid-derived aldehyde 4-hydroxy-2-nonenal, thereby protecting tissues from oxidative, allergic, and inflammatory damage, and has been implicated in the regulation of blastocyst implantation, angiogenesis, and tumor suppression through its ability to inhibit the transcription factor NF-κB and to prevent the activation of the NLRP3 inflammasome, making it a promising therapeutic target for respiratory, cardiovascular, renal, and neoplastic diseases.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy