SKU: 6956778293

CSF-1R Recombinant Rabbit mAb (S-467-26)

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Description

CSF-1R Recombinant Rabbit mAb (S-467-26)Product Specification Host Rabbit Antigen CSF 1R Synonyms Macrophage colony stimulating factor 1 receptor, CSF 1 receptor, CSF 1 R, M CSF R, Proto oncogene c Fms, CD115, FMS Immunogen Synthetic Peptide Location Cell membrane Accession P07333 Clone Number S 467 26 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Predicted Reactivity Ct Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical

Product Specification


Host Rabbit
Antigen CSF-1R
Synonyms Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, M-CSF-R, Proto-oncogene c-Fms, CD115, FMS
Immunogen Synthetic Peptide
Location Cell membrane
Accession P07333
Clone Number S-467-26
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P
Reactivity Hu, Ms, Rt
Predicted Reactivity Ct
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:500-1:1000
IHC-P 1:100

Background

Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded by the human CSF1R gene (known also as c-FMS). CSF1R is a receptor that can be activated by two ligands: colony stimulating factor 1 (CSF-1) and interleukin-34 (IL-34). CSF1R is highly expressed in myeloid cells, and CSF1R signaling is necessary for the survival, proliferation, and differentiation of many myeloid cell types in vivo and in vitro. CSF1R signaling is involved in many diseases and is targeted in therapies for cancer, neurodegeneration, and inflammatory bone diseases.

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SKU: 6956778293

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