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Description
TrkC Fc Chimera Protein, HumanProduct Specification Species Human Synonyms TrkC, Ntrk3 Accession Q96CY4 Amino Acid Sequence Cys32 Asp428, with C terminal Human IgG1 Fc
Product Specification
| Species | Human |
| Synonyms | TrkC, Ntrk3 |
| Accession | Q96CY4 |
| Amino Acid Sequence | Cys32-Asp428, with C-terminal Human IgG1 Fc CPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Expression System | HEK293 |
| Molecular Weight | 95-115kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Khotskaya Y B. et al. (2017). Targeting TRK family proteins in cancer. Review. 173:58-66. |
Background
The tropomyosin receptor kinase (TRK) family includes TRKA, TRKB, and TRKC proteins, which are encoded by NTRK1, NTRK2 and NTRK3 genes, respectively. Binding of neurotrophins to TRK proteins induces receptor dimerization, phosphorylation, and activation of the downstream signaling cascades via PI3K, RAS/MAPK/ERK, and PLC-gamma. TrkC functions not only as an oncogene, but also act as a tumor suppressor via a manner of dependence receptor in human malignant tumors. TrkC is a potent oncoprotein expressed in tumors derived from multiple cell lineages, and functions as an active protein tyrosine kinase by neurotrophin-3 (NT-3).
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4.6 ★★★★★
Based on 27 reviews
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Product Reviews
★★★★★ 3
Pretty not practical
Size: Queen (90"x90"), Color: Tiger Print Brown
I want to like this blanket because it’s soft and pretty but it’s unfortunately one of the most annoying blankets I’ve ever had. I got this blanket to replace my comforter for summer because it’s too hot and this blanket wouldn’t be. Well because or of it’s soft underneath and the fact that the two layers are only sewn together at the edges all night long it rolls into itself and won’t stay in place. I’ve tried tucking it under my mattress but by morning my bottom half is freezing while my top half sweats because the entire blanket will have slid up.
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Reviewed in the United States on May 15, 2026
★★★★★ 5
Comfortable and durable
Size: King (104"x90"), Color: Cheetah Print Brown
I love this comforter. It has survived many washes and 3 dogs sleeping in it every night with no issues. It looks great in my room and is very comfortable.
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Reviewed in the United States on May 13, 2026
★★★★★ 5
Noce product2
Size: Queen (90"x90"), Color: Tiger Print Brown
I use this regularly. It washes well. It is very warm and cozy.
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Reviewed in the United States on May 2, 2026
★★★★★ 5
Best blanket I’ve ever had
This blanket is super light but SOOOOO soft I’m absolutely in love with this blanket!!! My kids love it too!
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Reviewed in the United States on February 28, 2026
★★★★★ 5
Wasn't a bad purchase
Size: Queen (90"x90"), Color: Cheetah Print Pink
Good blanket
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Reviewed in the United States on May 11, 2026
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