SKU: 67604960522

Alexa Fluor® 700 Mouse Anti-Human CD45RO Antibody (S-R401)

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Description

Alexa Fluor® 700 Mouse Anti-Human CD45RO Antibody (S-R401)Product Specification Host Mouse Antigen CD45RO Synonyms Receptor type tyrosine protein phosphatase C; Leukocyte common antigen (L CA); T200; CD45; PTPRC Location Cell membrane, Synapse Accession P08575 Clone Number S R401 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Hu Purification Protein A Concentration 0. 2 mg ml Conjugation Alexa Fluor 700 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability &

Product Specification


Host Mouse
Antigen CD45RO
Synonyms Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen (L-CA); T200; CD45; PTPRC
Location Cell membrane, Synapse
Accession P08575
Clone Number S-R401
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Hu
Purification Protein A
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 700
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD45RO is a transmembrane protein tyrosine phosphatase with a molecular weight of approximately 180-220 kDa, belonging to a splice variant of the leukocyte common antigen CD45 family. It is generated through alternative splicing of the CD45 gene, lacking the exon-encoded A, B, and C regions, thus possessing the smallest extracellular domain among CD45 isoforms. CD45RO is predominantly expressed on memory T cells (including effector memory T cells and central memory T cells), activated T cells, monocytes, and macrophages, serving as a key surface marker for memory T cells. Its intracellular domain contains two highly conserved protein tyrosine phosphatase domains, which regulate the phosphorylation status of Src family kinases (e.g., Lck and Fyn) and play a crucial role in T-cell receptor (TCR) signaling, modulating T-cell activation, proliferation, and immune responses. CD45RO expression is closely associated with pathological processes such as chronic inflammation, autoimmune diseases, and transplant rejection, and it is also an important indicator for assessing T-cell immune function in HIV infection. Given its dynamic expression levels reflecting immune status, CD45RO holds potential value in immune monitoring and disease diagnosis.

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SKU: 67604960522

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ajn
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★★★★★ 5
Excellent athletic socks
Size: Large, Color: (100) White / White / Black
Solid athletic socks at a great price. Not too thick, not too thin. Second time I've purchased them. They last longer than most socks I've used in the past too. Only concern is the sizing. I may be reading the sizing chart wrong, but for my size 13 feet it says XL are the correct sock size. I've ordered Large twice and they're perfect. I would imagine the size Large socks would also fit up to size 14 shoe, but probably need to go with XL if foot is lager than 14.
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Reviewed in the United States on April 12, 2026
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Kevin March
Los Angeles, US
★★★★★ 4
Great product
Size: Large, Color: (035) Steel / White / Black
Comfortable fit perfect
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Reviewed in the United States on March 15, 2026
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Wesley
Carnegie, US
★★★★★ 5
Quality No Show Socks That Are Comfortable and Durable
Size: Large, Color: (100) White / White / Black
These Under Armour no show socks are great for everyday training and casual wear. The cotton blend feels comfortable and they stay in place throughout the day. Getting six pairs in a pack is solid value for a quality brand. They hold up well after multiple washes and the no show style works great with most athletic shoes. A reliable go-to sock.
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Reviewed in the United States on April 30, 2026
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Hanson
Carnegie, US
★★★★★ 5
Comfortable
Size: Large, Color: (001) Black / Black / White
I recently picked up a pair of Under Armour socks, and they’ve quickly become my go-to choice for daily wear and workouts. From the first wear, the fit felt snug and supportive without being too tight. The fabric is lightweight yet durable, and it does a great job wicking sweat — keeping my feet dry even during longer runs or intense gym sessions. One of the things I appreciate most is the arch support and cushioning in the right places. It adds just enough padding where I need it, especially under the ball and heel of the foot, which makes a noticeable difference on days when I’m on my feet a lot. The socks also have a nice breathable mesh pattern that improves airflow.
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Reviewed in the United States on January 4, 2026
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★★★★★ 5
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