SKU: 65890219161

Alexa Fluor® 700 Armenian hamster Anti-Mouse CD69 Antibody (S-R555)

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Description

Alexa Fluor® 700 Armenian hamster Anti-Mouse CD69 Antibody (S-R555)Product Specification Host Armenian hamster Antigen CD69 Synonyms Early activation antigen CD69; Cd69 Location Cell membrane Accession P37217 Clone Number S R555 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms Positive Sample ConA treated with C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 700 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability &

Product Specification


Host Armenian hamster
Antigen CD69
Synonyms Early activation antigen CD69; Cd69
Location Cell membrane
Accession P37217
Clone Number S-R555
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Ms
Positive Sample ConA treated with C57BL/6 mouse splenocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 700
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

CD69 is a type II transmembrane C-type lectin protein encoded by the CD69 gene, located on chromosome 12 in humans. It is a homodimer composed of two differentially glycosylated subunits (28–32 kDa), each containing an extracellular C-type lectin domain (CTLD), a transmembrane region, and a short cytoplasmic tail. CD69 is an early activation marker rapidly upregulated on the surface of T cells, B cells, and natural killer (NK) cells after stimulation. Its expression is regulated by transcription factors such as NF-κB, AP-1, and ERG-1. Functionally, CD69 plays a crucial role in lymphocyte proliferation, cytokine production, and retention in lymphoid tissues by interacting with molecules like S1P1 and Myl9/12. It is also implicated in the regulation of immune responses in various inflammatory and autoimmune conditions.

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SKU: 65890219161

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4.2 ★★★★★
Based on 27 reviews
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E
Verified Purchase
Elizabeth Alfaro
Lexington, US
★★★★★ 4
American Bully Trial - Honest Review
Color: Cyan NylonFish
I have never gotten a toy that lasted more than an hour when it comes to my baby girl. She is an aggressive chewer and loves anything that squeaks. This definitely helped to keep her entertained and use her teeth. I can confidently say that this toy may last a long time but she has already ripped a piece from it. I didn’t expect anything less since she always knows how to test new toys lol. I would definitely recommend though and will be getting more for her once this one is gone. Thank you!
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Reviewed in the United States on July 2, 2024
K
Verified Purchase
keyjustice
Carnegie, US
★★★★★ 3
Hard, heavy, sharp
Color: Cyan NylonFish
This is very durable, but it is also very heavy (our dog likes to throw her toys) and after some chewing, the head and tail are very sharp
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Reviewed in the United States on April 25, 2026
B
Verified Purchase
BellaGi
Boise, US
★★★★★ 5
2 years later and it’s still going!
Color: Cyan NylonFish, Color: Cyan NylonFish
I have 2 dogs, a 6lb chihuahua (Lolli) and an almost 100lb German shepherd/Belgian Malinois (Uzi). Got this for Uzi, however, Lolli had other plans for it. She literally took it out her mouth and ran to hide it. It’s been over a year, closer to 2 and it’s still hanging on. Attached a photo of Lolli…
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Reviewed in the United States on May 19, 2026
S
Verified Purchase
steven casteel
Alexandria, US
★★★★★ 5
Best found
Color: Cyan NylonFish
I have a heavy heavy chewer, the only things that has escaped him were items like "kong" solid and rubber but no squeaky. He quickly lost interest in the toy; largely within a week at most and never picks it up again unless really bored. Squeaky toys had a life shelf of a week at best, that is with us taking them away to "preserve" them for longer. So far, this toy, the fish, has been the longest surviving squeaky and the longest at keeping his interest. it has received some cosmetic damage, but nothing that would make you remove the toy from his possession and it STILL squeaks.
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Reviewed in the United States on October 20, 2024
C
Verified Purchase
Courtney
Lexington, US
★★★★★ 4
Still holding up to my super-chewer!
Color: Cyan NylonFish, Color: Cyan NylonFish
It's a very good product. I would recommend this toy for a heavy chewing dog. My main reasons it's not 5 stars, it's HEAVY and the eyes peeled right off. My pup really likes to throw his toys around, this thing sounds like a cannon ball that's going to go through our floor! He also tries to destroy everything so he was chewing on the eyes and he would have definitely eaten them if I wasn't paying attention. It's not a horrible thing but I obviously don't want him to eat non food things. My dog also likes the squeaker in it, but it's difficult for me to get it to squeak. That's not a big deal though just thought I should mention it. Overall especially for the price, it's a good sturdy product that's cute and it's still holding up. He's chewed parts of the softer areas off a bit, but the rest is very hard so he hasn't made much of a dent. It's also about as big as his head, so he's pretty happy with it!
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Reviewed in the United States on January 18, 2025

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